國立虎尾科技大學 |

Role of signaling pathways in brain tumorigenesis

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Role of signaling pathways in brain tumorigenesis/ by Mehdi Hayat Shahi.
作者:	Shahi, Mehdi Hayat.
出版者:	Singapore :Springer Nature Singapore : : 2023.,
面頁冊數:	xiii, 218 p. :illustrations, digital ; : 24 cm.;
Contained By:	Springer Nature eBook
標題:	Brain - Tumors -
電子資源:	https://doi.org/10.1007/978-981-15-8473-2
ISBN:	9789811584732

Role of signaling pathways in brain tumorigenesis
Shahi, Mehdi Hayat.

Role of signaling pathways in brain tumorigenesis[electronic resource] /by Mehdi Hayat Shahi. - Singapore :Springer Nature Singapore :2023. - xiii, 218 p. :illustrations, digital ;24 cm.

Introduction of Cell signalling Pathways and Brain Tumours -- Wnt cell signalling pathway and brain tumours development -- Notch cell signalling pathway and Brain Tumours -- Shh cell signalling pathway and paediatric brain tumour "Medulloblastoma" -- Role of Shh cell signalling pathway in "glioma" -- Role of stem cell marker NANOG in brain tumours development -- Stem cell factor Sox2 and Brain Tumours Development -- Role of Neurotrophins in brain tumor development -- Role of NFkβ in brain tumour development -- Role of Myc in brain tumours development -- Role of P53 in Medulloblastoma Development -- Role of Gene TP53 in glioblastoma development -- Role of HIF-1 in Brain Tumour Development -- EGFR and its role in glioma development -- Role of EFGR in medulloblastoma development -- Role of OCT4 in glioblastoma development -- Role of OCT4 in paediatric brain tumour "medulloblastoma" development -- Role of Mitogen activated protein (MAP) Kinase in paediatric brain tumour "medulloblastoma".

This book provides acomprehensive overview of cell signalling pathways and morphogens in the genesis of brain tumours. It also explains the role of brain tumour stem cells in the brain tumour progression. It also elucidates the novel early biomarkers that can be utilized to diagnose brain tumours. It presents the basic developmental pathways and morphogens, including retinoic acid and TGF-b that promote brain tumorigenesis. The chapters illustrate the role of stem cells and stem cells mediated cell signalling pathways including, Sonic hedgehog, Notch, Wnt in the brain tumour growth. The chapters also emphasize the role of transcription factors, mainlyNanog, Sox, BMI1, HIF1 and Pax6 in the brain tumouriogensis. It highlights the role of NF-kb, Myc and neurotrophins in the brain tumour development. Finally, the book summarizes the potential early therapeutic targets and targeted drug discovery for brain tumours.

ISBN: 9789811584732

Standard No.: 10.1007/978-981-15-8473-2doiSubjects--Topical Terms:

1434828
Brain
--Tumors

LC Class. No.: RC280.B7

Dewey Class. No.: 616.99481

Role of signaling pathways in brain tumorigenesis
LDR:02896nam a2200325 a 4500 001 1119914
003 DE-He213
005 20231120103301.0
006 m d
007 cr nn 008maaau
008 240612s2023 si s 0 eng d
020 $a 9789811584732 $q (electronic bk.)
020 $a 9789811584725 $q (paper)
024 7 $a 10.1007/978-981-15-8473-2 $2 doi
035 $a 978-981-15-8473-2
040 $a GP $c GP
041 0 $a eng
050 4 $a RC280.B7
072 7 $a MBGR $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MBGR $2 thema
082 0 4 $a 616.99481 $2 23
090 $a RC280.B7 $b S525 2023
100 1 $a Shahi, Mehdi Hayat. $3 1434827
245 1 0 $a Role of signaling pathways in brain tumorigenesis $h [electronic resource] / $c by Mehdi Hayat Shahi.
260 $a Singapore : $c 2023. $b Springer Nature Singapore : $b Imprint: Springer,
300 $a xiii, 218 p. : $b illustrations, digital ; $c 24 cm.
505 0 $a Introduction of Cell signalling Pathways and Brain Tumours -- Wnt cell signalling pathway and brain tumours development -- Notch cell signalling pathway and Brain Tumours -- Shh cell signalling pathway and paediatric brain tumour "Medulloblastoma" -- Role of Shh cell signalling pathway in "glioma" -- Role of stem cell marker NANOG in brain tumours development -- Stem cell factor Sox2 and Brain Tumours Development -- Role of Neurotrophins in brain tumor development -- Role of NFkβ in brain tumour development -- Role of Myc in brain tumours development -- Role of P53 in Medulloblastoma Development -- Role of Gene TP53 in glioblastoma development -- Role of HIF-1 in Brain Tumour Development -- EGFR and its role in glioma development -- Role of EFGR in medulloblastoma development -- Role of OCT4 in glioblastoma development -- Role of OCT4 in paediatric brain tumour "medulloblastoma" development -- Role of Mitogen activated protein (MAP) Kinase in paediatric brain tumour "medulloblastoma".
520 $a This book provides acomprehensive overview of cell signalling pathways and morphogens in the genesis of brain tumours. It also explains the role of brain tumour stem cells in the brain tumour progression. It also elucidates the novel early biomarkers that can be utilized to diagnose brain tumours. It presents the basic developmental pathways and morphogens, including retinoic acid and TGF-b that promote brain tumorigenesis. The chapters illustrate the role of stem cells and stem cells mediated cell signalling pathways including, Sonic hedgehog, Notch, Wnt in the brain tumour growth. The chapters also emphasize the role of transcription factors, mainlyNanog, Sox, BMI1, HIF1 and Pax6 in the brain tumouriogensis. It highlights the role of NF-kb, Myc and neurotrophins in the brain tumour development. Finally, the book summarizes the potential early therapeutic targets and targeted drug discovery for brain tumours.
650 0 $a Brain $x Tumors $x Pathogenesis. $3 1434828
650 0 $a Cellular signal transduction. $3 582607
650 0 $a Brain $x Tumors $x Treatment. $3 783761
650 1 4 $a Biomedical Research. $3 643481
650 2 4 $a Zoology. $3 593903
650 2 4 $a Medical Genetics. $3 1366169
650 2 4 $a Cytokines and Growth Factors. $3 787581
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-981-15-8473-2
950 $a Medicine (SpringerNature-11650)