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2023 medicinal chemistry reviews /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	2023 medicinal chemistry reviews // Joachim Rudolph and Joanne J. Bronson, editors.
remainder title:	ACS Medicinal chemistry reviews
other author:	Rudolph, Joachim,
Description:	1 online resource (xx, 798 pages) :illustrations. :
Subject:	Pharmaceutical chemistry. -
Online resource:	http://dx.doi.org/10.1021/mc-2023-vol58
ISBN:	9781734427462

2023 medicinal chemistry reviews /
2023 medicinal chemistry reviews /ACS Medicinal chemistry reviewsJoachim Rudolph and Joanne J. Bronson, editors. - 1 online resource (xx, 798 pages) :illustrations. - Medicinal Chemistry Reviews,Vol. 582575-9175 ;. - Medicinal Chemistry Reviews,Vol. 58..

Includes bibliographical references and index.

Contributors --John A. Lowe, III --

"Medicinal Chemistry Reviews (MCR) furnishes readers with a clear and succinct account of significant developments published during the past two to three years in major fields within medicinal chemistry. The chapters are not intended to be exhaustive but should provide the reader with ample lead reference material to pursue the subject to whatever depth he/she desires. Because of space and time limitations, chapters are not expected to replace or compete with the many books or extensive reviews published elsewhere. The book is not a vehicle for authors to present unpublished work."--

ISBN: 9781734427462

Standard No.: 10.1021/mc-2023-vol58Subjects--Topical Terms:

581965
Pharmaceutical chemistry.
Index Terms--Genre/Form:

554714
Electronic books.

LC Class. No.: RS402 / .A65 2023eb

Dewey Class. No.: 615.08

National Library of Medicine Call No.: W1 / A65

2023 medicinal chemistry reviews /
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245 0 0 $a 2023 medicinal chemistry reviews / $c Joachim Rudolph and Joanne J. Bronson, editors.
246 1 $a ACS Medicinal chemistry reviews
264 1 $a Washington, DC, USA : $b American Chemical Society, $c 2023.
300 $a 1 online resource (xx, 798 pages) : $b illustrations.
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490 1 $a Medicinal Chemistry Reviews, $x 2575-9175 ; $v Vol. 58
504 $a Includes bibliographical references and index.
505 0 0 $t Contributors -- $t Preface -- $t 1. My Career in Medicinal Chemistry / $r John A. Lowe, III -- $t 2. You Can't Always Get What You Want. But if You Try Sometimes, You Get What You Need: Insights from My Unlikely Career in Drug Development / $r Dennis Liotta -- $t Section 1: Central Nervous System Diseases, Neuroinflammation, and Pain Section Editor / $r Emily A. Peterson, Corey R. Hopkins -- $t 3. The Serotonin 5-HT2A Receptor as an Evolving Neurotherapeutic Target / $r Andrew A. Bolinger, Noelle C. Anastasio, Kathryn A. Cunningham, Jia Zhou -- $t 4. Recent Developments in the Discovery of Brain-Penetrant RIP1 Inhibitors / $r Craig E. Stivala, Domagoj Vucic -- $t Section 2: Cardiovascular, Metabolic, and Fibrotic Diseases / $r Section Editors: Johan D. Oslob, Antonio Romero -- $t 5. Advances Toward an Oral Non-Peptide Agonist of the GLP-1 Receptor / $r Todd Fields, Eric M. Woerly, Michael G. Bell, Kyle W. Sloop, Joseph D. Ho -- $t 6. Recent Advances in Small-Molecule Inhibitors of Ketohexokinase (KHK) / $r David C. Ebner, Gregory J. Tesz, Kentaro Futatsugi -- $t Section 3: Immunologic, Inflammatory, and Respiratory Diseases / $r Section Editors: J. Michael Ellis, Jennifer D. Venable -- $t 7. Targeting Selective Tyrosine Kinase 2 (TYK2) Inhibitors for the Treatment of Autoimmune Diseases / $r Silvana Leit, Bhaskar Srivastava, Nathan E. Genung, Joshua J. -- $t 8. An Integrin Renaissance: Recent Progress of Integrin Modulators in the Clinic / $r Darren Finkelstein, Timothy D. Machajewski -- $t 9. Salt-Inducible Kinases: An Emerging Target Class With Broad Therapeutic Potential / $r Nicolas Desroy, Christophe Peixoto, Steve De Vos -- $t Section 4: Oncology / $r Section Editors: Jason Kettle, Scott D. Edmondson -- $t 10. Small Molecule Degraders of Ikaros Zinc Finger (IKZF) Transcription Factors / $r Natalie Holmberg-Douglas, Hunter Shunatona, Godwin Kumi, Ashok Purandare -- $t 11. Recent Advances in Targeting the PRMT5/MTA Complex / $r Christopher R. Smith, Matthew A. Marx -- $t 12. Recent Advances in the Discovery of Cyclin-Dependent Kinase 2 (CDK2) Selective Inhibitors / $r Kevin D. Freeman-Cook, Robert L. Hoffman -- $t Section 5: Infectious Diseases / $r Section Editors: William J. Watkins, Adam S. Duerfeldt -- $t 13. Recent Advances in the Discovery of Antimicrobial Natural Products through Synthetic Means / $r M. Alejandro Valdes-Pena, Joshua G. Pierce -- $t 14. Practical Applications of Machine Learning for Anti-Infective Drug Discovery Nishant Sarkar, Jonathan M. Stokes --
505 0 0 $t 15. Recent Progress in Antivirals Against Zika Virus María-Jesús Pérez-Pérez, Eva-María Priego, Miguel A. Martín-Acebes -- $t Section 6: Topics in Biology / $r Section Editors: John A. Lowe III, Amanda L. Garner -- $t 16. Small-Molecule RNA-Splicing Modulators / $r Hasane Ratni, Kathleen D. McCarthy, Joseph L. Duffy, Sergey V. Paushkin, Sivaraman Dandapani -- $t 17. Small-Molecule Interactions With Biomolecular Condensates / $r George S. Tria, Joseph W. Tucker, Mary E. Spilker, Brooke A. Conti, Mariano Oppikofer -- $t Section 7: Topics in Drug Design and Discovery / $r Section Editors: Brad M. Savall, Matthew Bourbeau -- $t 18. The Rise, Fall, and Future Promise of IDO1 Inhibitors for Immuno-Oncology / $r Emily C. Cherney, David K. Williams, Liping Zhang, Susheel J. Nara -- $t 19. Drug-Induced Liver Injury: Mechanisms, Methods, Pre-Clincial Assessment, and a Medicinal Chemist's Perspective / $r Anh T. Tran, James J. Crawford, Debashis Mandal, Tezcan Guney, Jamie Karmel -- $t 20. Non-Cyclic Dinucleotide STING Agonists for Immuno-Oncology / $r Julian C. Lo, Emily C. Cherney -- $t Section 8: Case Histories and New Chemical Entities / $r Section Editors: Brian G. Lawhorn, Peter S. Dragovich -- $t 21. Case History: Discovery and Development of Verquvo(R) (Vericiguat), a Soluble Guanylate Cyclase (sGC) Stimulator for the Treatment of Chronic Heart Failure / $r Markus Follmann, Corina Becker, Lothar Roessig, Peter Sandner, Johannes-Peter Stasch -- $t 22. Case History: Corectim(R) (Delgocitinib), The First Topical JAK Inhibitor for the Treatment of Atopic Dermatitis / $r Makoto Shiozaki -- $t 23. New Chemical Entities Entering Phase III Trials in 2022 Matthew L. Condakes, Jennifer Jiang, David W. Lin, Rhiannon Thomas-Tran, Juan del Pozo, Christiana N. -- $t 24. To Market, to Market-2022: Small Molecules / $r Erika Araujo, Ian M. Bell, Alexander Burckle, Dennis C. Koester, James R. Manning, Georgette Castanedo, Mingshuo Zeng, T. G. Murali Dhar, Natalie Holmberg-Douglas, Eric R. Welin, J. Robert Merritt, Kevin M. Peese, Joanne J. Bronson -- $t 25. To Market, to Market-2022: Macromolecular Therapeutics / $r Shion A. Lim, Nicholas J. Agard, Ryan L. Kelly, Benjamin N. Bell, Si-Jie Chen, Anna M. Gram, J. Robert Merritt, Ian Moench, Katarina Pance, Tatjana Petojevic -- $t Indices -- $t Keyword Index, Volume 58 -- $t Cumulative NCE Introduction Index, 2014-22 -- $t Cumulative NCE Introduction Index (by Indication), 2014-22
520 $a "Medicinal Chemistry Reviews (MCR) furnishes readers with a clear and succinct account of significant developments published during the past two to three years in major fields within medicinal chemistry. The chapters are not intended to be exhaustive but should provide the reader with ample lead reference material to pursue the subject to whatever depth he/she desires. Because of space and time limitations, chapters are not expected to replace or compete with the many books or extensive reviews published elsewhere. The book is not a vehicle for authors to present unpublished work."-- $c Provided by publisher.
650 0 $a Pharmaceutical chemistry. $3 581965
650 0 $a Clinical chemistry. $3 857402
655 0 $a Electronic books. $2 local $3 554714
700 1 $a Rudolph, Joachim, $e editor. $u Genentech, South San Francisco, California, U.S.A. $3 1436989
700 1 $a Bronson, Joanne J., $e editor. $u Bristol Myers Squibb, Cambridge, Massachusetts, U.S.A. $3 1436990
710 2 $a American Chemical Society. $3 1436935
710 2 $a American Chemical Society. $b Division of Medicinal Chemistry. $3 1436991
830 0 $a Medicinal Chemistry Reviews, $x 2575-9175 ; $v Vol. 58. $3 1436992
856 4 $u http://dx.doi.org/10.1021/mc-2023-vol58