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Protein condensation : = kinetic pathways to crystallization and disease /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Protein condensation :/ J.D. Gunton, A. Shiryayev, and D.L. Pagan.
Reminder of title:	kinetic pathways to crystallization and disease /
Author:	Gunton, J. D.
other author:	Shiryayev, A.
Description:	1 online resource (xii, 364 pages) :digital, PDF file(s). :
Notes:	Title from publisher's bibliographic system (viewed on 05 Oct 2015).
Subject:	Proteins. -
Online resource:	https://doi.org/10.1017/CBO9780511535321
ISBN:	9780511535321 (ebook)

Protein condensation : = kinetic pathways to crystallization and disease /
Gunton, J. D.1937-

Protein condensation :kinetic pathways to crystallization and disease /J.D. Gunton, A. Shiryayev, and D.L. Pagan. - 1 online resource (xii, 364 pages) :digital, PDF file(s).

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Globular protein structure -- Experimental methods -- Thermodynamics and statistical mechanics -- Protein-protein interactions -- Theoretical studies of equilibrium -- Nucleation theory -- Experimental studies of nucleation -- Lysozyme -- Some other globular proteins -- Membrane proteins -- Crystallins and cataracts -- Sickle hemoglobin and sickle cell anemia -- Alzheimer's disease.

The quest to understand the condensation of proteins from solutions is a rapidly evolving field. The purpose of this book is to bring to an interdisciplinary audience the state-of-the-art in current research. The first part of the book deals with issues related to the production of high quality protein crystals from solution. Since protein function is determined by structure, high quality protein crystals must be grown in order to determine their structure by X-ray crystallography. The book also discusses diseases that occur due to undesired protein condensation, an increasingly important subject. Examples include sickle cell anemia, cataracts and Alzheimer's disease. Current experimental and theoretical work on these diseases is discussed, which seeks understanding at a fundamental, molecular level, to prevent the undesired condensation from occurring. The book, containing color plate sections, is suitable for graduate students and academic researchers in physics, chemistry, structural biology, protein crystallography and medicine.

ISBN: 9780511535321 (ebook)Subjects--Topical Terms:

584006
Proteins.

LC Class. No.: QP551 / .G86 2007

Dewey Class. No.: 572.633

Protein condensation : = kinetic pathways to crystallization and disease /
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245 1 0 $a Protein condensation : $b kinetic pathways to crystallization and disease / $c J.D. Gunton, A. Shiryayev, and D.L. Pagan.
264 1 $a Cambridge : $b Cambridge University Press, $c 2007.
300 $a 1 online resource (xii, 364 pages) : $b digital, PDF file(s).
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500 $a Title from publisher's bibliographic system (viewed on 05 Oct 2015).
505 0 $a Globular protein structure -- Experimental methods -- Thermodynamics and statistical mechanics -- Protein-protein interactions -- Theoretical studies of equilibrium -- Nucleation theory -- Experimental studies of nucleation -- Lysozyme -- Some other globular proteins -- Membrane proteins -- Crystallins and cataracts -- Sickle hemoglobin and sickle cell anemia -- Alzheimer's disease.
520 $a The quest to understand the condensation of proteins from solutions is a rapidly evolving field. The purpose of this book is to bring to an interdisciplinary audience the state-of-the-art in current research. The first part of the book deals with issues related to the production of high quality protein crystals from solution. Since protein function is determined by structure, high quality protein crystals must be grown in order to determine their structure by X-ray crystallography. The book also discusses diseases that occur due to undesired protein condensation, an increasingly important subject. Examples include sickle cell anemia, cataracts and Alzheimer's disease. Current experimental and theoretical work on these diseases is discussed, which seeks understanding at a fundamental, molecular level, to prevent the undesired condensation from occurring. The book, containing color plate sections, is suitable for graduate students and academic researchers in physics, chemistry, structural biology, protein crystallography and medicine.
650 0 $a Proteins. $3 584006
650 0 $a Condensation. $3 592130
700 1 $a Shiryayev, A. $q (Andrey), $e author. $3 1445664
700 1 $a Pagan, D. L. $q (Daniel L.), $e author. $3 1445665
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856 4 0 $u https://doi.org/10.1017/CBO9780511535321