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Senotherapy = a potential pharmacological strategy for prolonging human lifespan and healthspan /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Senotherapy/ by Gabriel Bennett.
Reminder of title:	a potential pharmacological strategy for prolonging human lifespan and healthspan /
Author:	Bennett, Gabriel.
Published:	Singapore :Springer Nature Singapore : : 2024.,
Description:	xvii, 100 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer Nature eBook
Subject:	Cells - Aging. -
Online resource:	https://doi.org/10.1007/978-981-97-3637-9
ISBN:	9789819736379

Senotherapy = a potential pharmacological strategy for prolonging human lifespan and healthspan /
Bennett, Gabriel.

Senotherapya potential pharmacological strategy for prolonging human lifespan and healthspan /[electronic resource] :by Gabriel Bennett. - Singapore :Springer Nature Singapore :2024. - xvii, 100 p. :ill. (some col.), digital ;24 cm. - SpringerBriefs in modern perspectives on disability research,3004-9717. - SpringerBriefs in modern perspectives on disability research..

Chapter 1. Introduction to Senotherapies -- Chapter 2. The Accumulation of Senescent Cells and Disease -- Chapter 3. Current Research about Senotheraputics -- Chapter 4. Final Comments -- Appendices.

Historically, ageing has been regarded as a biological process that is unalterable. Although it is not possible to halt or reverse this process, medical scientists are currently attempting to extend lifespan and healthspan by developing treatments that ensure that the hallmarks of ageing do not resemble someone who is elderly. The accumulation of senescent cells is a hallmark of biological ageing. It is speculated that once the volume of senescent cells exceeds a safe therapeutic threshold the possibility of developing age-associated diseases increases. Senotherapeutic medications, otherwise known as senotherapy, aim to keep the volume of senescent cells below this threshold. These medications either eliminate senescent cells (i.e., senolytic medications) or prevent healthy cells from becoming senescent (i.e., senomorphic medications) While preliminary research shows that senotherapy is a promising strategy for increasing both human lifespan and healthspan, there nevertheless remains many unanswered questions. This book summarises our current research about senescent cell accumulation and age-associated diseases, human trials of senotherapeutic medications, and topics about senotherapy that require more research.

ISBN: 9789819736379

Standard No.: 10.1007/978-981-97-3637-9doiSubjects--Topical Terms:

582177
Cells
--Aging.

LC Class. No.: RC952.5

Dewey Class. No.: 615.547

Senotherapy = a potential pharmacological strategy for prolonging human lifespan and healthspan /
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