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Chemistry and biology of O-GlcNAcylation

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Chemistry and biology of O-GlcNAcylation/ edited by Wen Yi.
other author:	Yi, Wen.
Published:	Singapore :Springer Nature Singapore : : 2024.,
Description:	vii, 178 p. :ill. (chiefly color), digital ; : 24 cm.;
Contained By:	Springer Nature eBook
Subject:	Glycosylation. -
Online resource:	https://doi.org/10.1007/978-981-97-4864-8
ISBN:	9789819748648

Chemistry and biology of O-GlcNAcylation
Chemistry and biology of O-GlcNAcylation[electronic resource] /edited by Wen Yi. - Singapore :Springer Nature Singapore :2024. - vii, 178 p. :ill. (chiefly color), digital ;24 cm.

Chapter 1. Chemical tools for decoding the functions of O-GlcNAcylation -- Chapter 2. Profiling O-GlcNAcylation with mass spectrometry -- Chapter 3. O-GlcNAcylation and cell metabolism -- Chapter 4. O-GlcNAcylation and transcriptional regulation and epigenetics -- Chapter 5. O-GlcNAcylation and signal transduction -- Chapter 6. O-GlcNAcylation and stem cells -- Chapter 7. O-GlcNAcylation and immune regulation -- Chapter 8. O-GlcNAcylation and neuronal development, neurodegeneration and neurological disorders.

O-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and immune regulation. Given the critical role of O-GlcNAc in normal physiology, increasing evidence has now demonstrated that deregulation of O-GlcNAc is closely associated with the development and progression of various diseases, including neurodegeneration, cardiovascular disease, and cancer. This book provides a comprehensive overview of the current progress and understanding of this modification in biology, and likely provides new research directions in the future.

ISBN: 9789819748648

Standard No.: 10.1007/978-981-97-4864-8doiSubjects--Topical Terms:

779201
Glycosylation.

LC Class. No.: QP552.G59

Dewey Class. No.: 572.68

Chemistry and biology of O-GlcNAcylation
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505 0 $a Chapter 1. Chemical tools for decoding the functions of O-GlcNAcylation -- Chapter 2. Profiling O-GlcNAcylation with mass spectrometry -- Chapter 3. O-GlcNAcylation and cell metabolism -- Chapter 4. O-GlcNAcylation and transcriptional regulation and epigenetics -- Chapter 5. O-GlcNAcylation and signal transduction -- Chapter 6. O-GlcNAcylation and stem cells -- Chapter 7. O-GlcNAcylation and immune regulation -- Chapter 8. O-GlcNAcylation and neuronal development, neurodegeneration and neurological disorders.
520 $a O-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and immune regulation. Given the critical role of O-GlcNAc in normal physiology, increasing evidence has now demonstrated that deregulation of O-GlcNAc is closely associated with the development and progression of various diseases, including neurodegeneration, cardiovascular disease, and cancer. This book provides a comprehensive overview of the current progress and understanding of this modification in biology, and likely provides new research directions in the future.
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