國立虎尾科技大學 |

Evaluating the Role of the Bovine Vaginal Microbiome in Neonatal and Maternal Health Outcomes.

紀錄類型:	書目-語言資料,手稿 : Monograph/item
正題名/作者:	Evaluating the Role of the Bovine Vaginal Microbiome in Neonatal and Maternal Health Outcomes./
作者:	Messman, Riley D. .
面頁冊數:	1 online resource (158 pages)
附註:	Source: Dissertations Abstracts International, Volume: 85-02, Section: B.
Contained By:	Dissertations Abstracts International85-02B.
標題:	Animal sciences. -
電子資源:	click for full text (PQDT)
ISBN:	9798380119696

Evaluating the Role of the Bovine Vaginal Microbiome in Neonatal and Maternal Health Outcomes.
Messman, Riley D. .

Evaluating the Role of the Bovine Vaginal Microbiome in Neonatal and Maternal Health Outcomes. - 1 online resource (158 pages)

Source: Dissertations Abstracts International, Volume: 85-02, Section: B.

Thesis (Ph.D.)--Mississippi State University, 2023.

Includes bibliographical references

The dam vaginal microbiota is the first major microbial inoculating community within the neonate. The composition of the dam vaginal microbiota has implications in calf commensal microbiota development. Alterations of the dam microbial community prior to parturition could alter inoculating communities and immune responses in both the dam and calf. Thus, authors aimed to elucidate the microbial community composition of the bovine dam vaginal and calf nasal microbiota post-partum after utilizing betadine lavages (BL). The dam vaginal and calf nasal microbial communities and immune responses were evaluated at 0-, 15-, 30- and 60-day post-partum. Microbiota composition of the dam haircoat, udder, and IgG in the colostrum/calf sera were also evaluated at day 0. Serial BLG prior to parturition did not alter the alpha diversity of the dam-vaginal microbiota but did alter the calf-nasal microbiota at parturition (P = 0.03). Dams receiving BLG prior to calving had increased colostrum IgG concentrations compared to CON dams (P =0.04). These results suggest physiological insults (BLG) prior to parturition led to an increased immune response which altering dam colostrum IgG. Thus, neonatal colostrum consumption could drive immune responses against inoculating bacteria resulting in differing nasal microbial communities between treatment groups. The beta diversity of the calf nasal microbiota was significantly different at day 0 compared to all other timepoints (P = 0.006). The calf nasal beta diversity at day 15 was similar to day 30 (P = 0.38) but significantly different compared to day 60 (P = 0.006). There was no effect of time on altering the alpha (P = 0.60) or beta (P = 0.06) diversity of the dam vaginal microbiota. The calf nasal microbiota was different from the dam vaginal microbiota at all timepoints post-partum, regardless of treatment. At day 15, the alpha and beta diversity of calves was altered compared to day 0, suggestive of a reinoculation timepoint between 0 and 14 days of age. Together, this data contributes to the paucity within beef cattle dam-calf post-partum microbiota literature and provides directionality for future research objectives within this field.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798380119696Subjects--Topical Terms:

1178863
Animal sciences.
Subjects--Index Terms:

BovineIndex Terms--Genre/Form:

554714
Electronic books.

Evaluating the Role of the Bovine Vaginal Microbiome in Neonatal and Maternal Health Outcomes.
LDR:03568ntm a2200385K 4500 001 1141606
005 20240318062652.5
006 m o d
007 cr mn ---uuuuu
008 250605s2023 xx obm 000 0 eng d
020 $a 9798380119696
035 $a (MiAaPQ)AAI30574684
035 $a AAI30574684
040 $a MiAaPQ $b eng $c MiAaPQ $d NTU
100 1 $a Messman, Riley D. . $3 1465499
245 1 0 $a Evaluating the Role of the Bovine Vaginal Microbiome in Neonatal and Maternal Health Outcomes.
264 0 $c 2023
300 $a 1 online resource (158 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Dissertations Abstracts International, Volume: 85-02, Section: B.
500 $a Advisor: Lemley, Caleb O. .
502 $a Thesis (Ph.D.)--Mississippi State University, 2023.
504 $a Includes bibliographical references
520 $a The dam vaginal microbiota is the first major microbial inoculating community within the neonate. The composition of the dam vaginal microbiota has implications in calf commensal microbiota development. Alterations of the dam microbial community prior to parturition could alter inoculating communities and immune responses in both the dam and calf. Thus, authors aimed to elucidate the microbial community composition of the bovine dam vaginal and calf nasal microbiota post-partum after utilizing betadine lavages (BL). The dam vaginal and calf nasal microbial communities and immune responses were evaluated at 0-, 15-, 30- and 60-day post-partum. Microbiota composition of the dam haircoat, udder, and IgG in the colostrum/calf sera were also evaluated at day 0. Serial BLG prior to parturition did not alter the alpha diversity of the dam-vaginal microbiota but did alter the calf-nasal microbiota at parturition (P = 0.03). Dams receiving BLG prior to calving had increased colostrum IgG concentrations compared to CON dams (P =0.04). These results suggest physiological insults (BLG) prior to parturition led to an increased immune response which altering dam colostrum IgG. Thus, neonatal colostrum consumption could drive immune responses against inoculating bacteria resulting in differing nasal microbial communities between treatment groups. The beta diversity of the calf nasal microbiota was significantly different at day 0 compared to all other timepoints (P = 0.006). The calf nasal beta diversity at day 15 was similar to day 30 (P = 0.38) but significantly different compared to day 60 (P = 0.006). There was no effect of time on altering the alpha (P = 0.60) or beta (P = 0.06) diversity of the dam vaginal microbiota. The calf nasal microbiota was different from the dam vaginal microbiota at all timepoints post-partum, regardless of treatment. At day 15, the alpha and beta diversity of calves was altered compared to day 0, suggestive of a reinoculation timepoint between 0 and 14 days of age. Together, this data contributes to the paucity within beef cattle dam-calf post-partum microbiota literature and provides directionality for future research objectives within this field.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2024
538 $a Mode of access: World Wide Web
650 4 $a Animal sciences. $3 1178863
650 4 $a Obstetrics. $3 674110
653 $a Bovine
653 $a Microbiome
653 $a Neonatal inoculation
653 $a Reproduction
653 $a Maternal health
655 7 $a Electronic books. $2 local $3 554714
690 $a 0475
690 $a 0380
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a Mississippi State University. $b College of Agriculture and Life Sciences. $3 1465500
773 0 $t Dissertations Abstracts International $g 85-02B.
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30574684 $z click for full text (PQDT)