國立虎尾科技大學 |

Comparative Animal Mucomics.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Comparative Animal Mucomics./
Author:	Cerullo, Antonio R.
Description:	1 online resource (195 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 85-08, Section: B.
Contained By:	Dissertations Abstracts International85-08B.
Subject:	Biochemistry. -
Online resource:	click for full text (PQDT)
ISBN:	9798381682793

Comparative Animal Mucomics.
Cerullo, Antonio R.

Comparative Animal Mucomics. - 1 online resource (195 pages)

Source: Dissertations Abstracts International, Volume: 85-08, Section: B.

Thesis (Ph.D.)--City University of New York, 2024.

Includes bibliographical references

Mucus is one of Nature's most abundant and versatile biomaterials. These secretions are present in all animals, from the lowly garden snail to the great blue whale, and fulfill a multitude of functions, acting as antimicrobial barriers, moisturizers, adhesive glues, surface lubricants, and mineralizing agents. Despite their importance, very little is known about mucus compositions or properties. The largest challenge precluding the greater understanding of mucus function is its complexity; a single mucus contains complex mixtures of proteins, glycans, and ions that all have important roles in function. Therefore, understanding mucus function necessitates analysis that compares different mucus from one animal, or mucus of the same function from different species, and this approach must characterize mucus across the molecular-to-macroscopic continuum.This thesis aims to characterize the compositions and properties of animal mucus, determine the methods that best interrogate these materials, and justify the need to do so. Chapter 1 highlights secreted animal mucus diversity in Nature. Chapter 2 demonstrates our integrative omics approach comparing three mucus of different functions from the garden snail, Cornu aspersum. The Epilogue concludes with a call to expand mucus characterization efforts amidst a global biodiversity crisis.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798381682793Subjects--Topical Terms:

582831
Biochemistry.
Subjects--Index Terms:

AnimalsIndex Terms--Genre/Form:

554714
Electronic books.

Comparative Animal Mucomics.
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520 $a Mucus is one of Nature's most abundant and versatile biomaterials. These secretions are present in all animals, from the lowly garden snail to the great blue whale, and fulfill a multitude of functions, acting as antimicrobial barriers, moisturizers, adhesive glues, surface lubricants, and mineralizing agents. Despite their importance, very little is known about mucus compositions or properties. The largest challenge precluding the greater understanding of mucus function is its complexity; a single mucus contains complex mixtures of proteins, glycans, and ions that all have important roles in function. Therefore, understanding mucus function necessitates analysis that compares different mucus from one animal, or mucus of the same function from different species, and this approach must characterize mucus across the molecular-to-macroscopic continuum.This thesis aims to characterize the compositions and properties of animal mucus, determine the methods that best interrogate these materials, and justify the need to do so. Chapter 1 highlights secreted animal mucus diversity in Nature. Chapter 2 demonstrates our integrative omics approach comparing three mucus of different functions from the garden snail, Cornu aspersum. The Epilogue concludes with a call to expand mucus characterization efforts amidst a global biodiversity crisis.
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538 $a Mode of access: World Wide Web
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