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Effectiveness and Acceptability of Resistance Exercise Breaks as a Strategy to Augment Vascular Insulin Sensitivity During Prolonged Sitting in Sedentary Workers.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Effectiveness and Acceptability of Resistance Exercise Breaks as a Strategy to Augment Vascular Insulin Sensitivity During Prolonged Sitting in Sedentary Workers./
Author:	Rogers, Emily M.
Description:	1 online resource (112 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 85-01, Section: A.
Contained By:	Dissertations Abstracts International85-01A.
Subject:	Physiology. -
Online resource:	click for full text (PQDT)
ISBN:	9798379793920

Effectiveness and Acceptability of Resistance Exercise Breaks as a Strategy to Augment Vascular Insulin Sensitivity During Prolonged Sitting in Sedentary Workers.
Rogers, Emily M.

Effectiveness and Acceptability of Resistance Exercise Breaks as a Strategy to Augment Vascular Insulin Sensitivity During Prolonged Sitting in Sedentary Workers. - 1 online resource (112 pages)

Source: Dissertations Abstracts International, Volume: 85-01, Section: A.

Thesis (Ph.D.)--The University of Iowa, 2023.

Includes bibliographical references

Sedentary behavior time has increased significantly over the last few decades due to increased sitting in the workplace, social settings, and during transportation. As 80% of Americans work in primarily sedentary jobs, where many sit for ~7 h per day, the workplace serves as a prime environment to implement strategies to reduce sedentarism. It is highly likely that sedentary behavior promotes cardiometabolic disease (CMD) risk via detrimental impacts to nitric oxide (NO)-mediated endothelial function. Notably, after just 3 h of uninterrupted sitting, blood flow and laminar shear stress in conduit arteries is decreased, which promotes a proatherogenic hemodynamic environment, leaving the vasculature susceptible to atherosclerotic disease development. Evidence also demonstrates that laminar shear stress is important for sensitizing the endothelium to the vasodilatory effects of insulin. Thus, prolonged exposure to sedentary behavior likely promotes decrements in vascular insulin sensitivity (VIS). Importantly, resistance exercise breaks (REB), performed to break up prolonged sedentary bouts, can successfully attenuate sitting-induced impairments in popliteal and femoral artery FMD during sedentary periods lasting 3-5 h. However, the effects of REB performed during an otherwise sedentary period on VIS have not yet been explored. Therefore, the first aim of this dissertation was to examine if performing 3-min REB during a 3-h sedentary period could augment VIS in the face of prolonged sitting. The second aim of this dissertation was to assess the acceptability of these REB and to understand how they impact productivity, discomfort, and sleepiness.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798379793920Subjects--Topical Terms:

673386
Physiology.
Subjects--Index Terms:

Blood flowIndex Terms--Genre/Form:

554714
Electronic books.

Effectiveness and Acceptability of Resistance Exercise Breaks as a Strategy to Augment Vascular Insulin Sensitivity During Prolonged Sitting in Sedentary Workers.
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504 $a Includes bibliographical references
520 $a Sedentary behavior time has increased significantly over the last few decades due to increased sitting in the workplace, social settings, and during transportation. As 80% of Americans work in primarily sedentary jobs, where many sit for ~7 h per day, the workplace serves as a prime environment to implement strategies to reduce sedentarism. It is highly likely that sedentary behavior promotes cardiometabolic disease (CMD) risk via detrimental impacts to nitric oxide (NO)-mediated endothelial function. Notably, after just 3 h of uninterrupted sitting, blood flow and laminar shear stress in conduit arteries is decreased, which promotes a proatherogenic hemodynamic environment, leaving the vasculature susceptible to atherosclerotic disease development. Evidence also demonstrates that laminar shear stress is important for sensitizing the endothelium to the vasodilatory effects of insulin. Thus, prolonged exposure to sedentary behavior likely promotes decrements in vascular insulin sensitivity (VIS). Importantly, resistance exercise breaks (REB), performed to break up prolonged sedentary bouts, can successfully attenuate sitting-induced impairments in popliteal and femoral artery FMD during sedentary periods lasting 3-5 h. However, the effects of REB performed during an otherwise sedentary period on VIS have not yet been explored. Therefore, the first aim of this dissertation was to examine if performing 3-min REB during a 3-h sedentary period could augment VIS in the face of prolonged sitting. The second aim of this dissertation was to assess the acceptability of these REB and to understand how they impact productivity, discomfort, and sleepiness.
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