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The Combined Effects of Physical Exercise and Cognitive Training on Gait Speed and Primary Motor Cortex Metabolism in Individuals with Mild Cognitive Impairment : = A 1H-MRS Analysis.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	The Combined Effects of Physical Exercise and Cognitive Training on Gait Speed and Primary Motor Cortex Metabolism in Individuals with Mild Cognitive Impairment :/
Reminder of title:	A 1H-MRS Analysis.
Author:	Elkas, Jack Thomas Emsey.
Description:	1 online resource (92 pages)
Notes:	Source: Masters Abstracts International, Volume: 85-06.
Contained By:	Masters Abstracts International85-06.
Subject:	Exercise. -
Online resource:	click for full text (PQDT)
ISBN:	9798381023909

The Combined Effects of Physical Exercise and Cognitive Training on Gait Speed and Primary Motor Cortex Metabolism in Individuals with Mild Cognitive Impairment : = A 1H-MRS Analysis.
Elkas, Jack Thomas Emsey.

The Combined Effects of Physical Exercise and Cognitive Training on Gait Speed and Primary Motor Cortex Metabolism in Individuals with Mild Cognitive Impairment :A 1H-MRS Analysis. - 1 online resource (92 pages)

Source: Masters Abstracts International, Volume: 85-06.

Thesis (M.Sc.)--The University of Western Ontario (Canada), 2023.

Includes bibliographical references

Mild cognitive impairment (MCI) is a transitional stage before dementia. Altered gait in MCI has been associated with progression to dementia. Using magnetic resonance spectroscopy, a relationship between primary motor cortex (M1) neurochemistry and dual task gait speed has been reported in MCI. Interventional research suggests exercise, cognitive training, and vitamin D supplementation may benefit MCI, yet the combined effect of these treatments on gait speed and M1 metabolism is unknown. Participants with MCI (N=75) were assigned to one of five intervention arms and dual task cost on gait speed and M1 metabolism was assessed before and five months after intervention. Cognitive training paired with exercise increased M1 N-acetyl aspartate (NAA)/creatine concentrations compared to physical exercise alone. Additionally, those with greater changes in dual task cost on gait speed showed greater decreases in NAA and choline, further establishing a relationship between gait speed and M1 function in MCI.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798381023909Subjects--Topical Terms:

583899
Exercise.
Index Terms--Genre/Form:

554714
Electronic books.

The Combined Effects of Physical Exercise and Cognitive Training on Gait Speed and Primary Motor Cortex Metabolism in Individuals with Mild Cognitive Impairment : = A 1H-MRS Analysis.
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520 $a Mild cognitive impairment (MCI) is a transitional stage before dementia. Altered gait in MCI has been associated with progression to dementia. Using magnetic resonance spectroscopy, a relationship between primary motor cortex (M1) neurochemistry and dual task gait speed has been reported in MCI. Interventional research suggests exercise, cognitive training, and vitamin D supplementation may benefit MCI, yet the combined effect of these treatments on gait speed and M1 metabolism is unknown. Participants with MCI (N=75) were assigned to one of five intervention arms and dual task cost on gait speed and M1 metabolism was assessed before and five months after intervention. Cognitive training paired with exercise increased M1 N-acetyl aspartate (NAA)/creatine concentrations compared to physical exercise alone. Additionally, those with greater changes in dual task cost on gait speed showed greater decreases in NAA and choline, further establishing a relationship between gait speed and M1 function in MCI.
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