國立虎尾科技大學 |

Cannabis Substitution for Prescription Drugs : = Understanding Longitudinal Trends in the Era of Legal Cannabis.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Cannabis Substitution for Prescription Drugs :/
Reminder of title:	Understanding Longitudinal Trends in the Era of Legal Cannabis.
Author:	Strand, Lauren.
Description:	1 online resource (161 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 82-11, Section: B.
Contained By:	Dissertations Abstracts International82-11B.
Subject:	Law. -
Online resource:	click for full text (PQDT)
ISBN:	9798728230670

Cannabis Substitution for Prescription Drugs : = Understanding Longitudinal Trends in the Era of Legal Cannabis.
Strand, Lauren.

Cannabis Substitution for Prescription Drugs :Understanding Longitudinal Trends in the Era of Legal Cannabis. - 1 online resource (161 pages)

Source: Dissertations Abstracts International, Volume: 82-11, Section: B.

Thesis (Ph.D.)--University of Washington, 2021.

Includes bibliographical references

The effects of changes in cannabis laws continue to be of great interest to researchers, medical professionals, and policymakers as individual US states implement legal cannabis markets and cannabinoids are better studied. Cannabis may serve as a substitute for a number of substances including several classes of prescription drugs. In order to evaluate cannabis-for-prescription drug substitution in the period following legal dispensary opening in Washington State (July 2014-December 2017), we evaluated the effect of increased cannabis demand on opioid dispensing outcomes in individual counties. We instrumented county-quarter level cannabis sales using state-regulated dispensary density, estimating within-county changes in the number of individuals dispensed opioids per quarter. Effects of increasing retail cannabis sales on short- and long-term dispensing were small in magnitude and not statistically significant. Small effects for long-term high dose dispensing (approximately 3% of dispensing) may reflect substitution among the individuals at the highest risk for opioid use disorder; however, we did not find consistent evidence for substitution in the early period during recreational cannabis rollout in Washington. We also evaluated post-cannabis policy change substitution effects for antianxiety and antidepressant medication use in their respective indications among individuals with employer-sponsored insurance within US states (2010-2017). Medical cannabis policy did not lead to measurable changes in the level of use of antianxiety medications or antidepressants within their respective conditions; however, there may be noteworthy state and time-related heterogeneity as evidenced in event studies. In synthetic control models for Colorado and Washington, which legalized recreational cannabis in 2012, the use of antianxiety medications in anxiety and antidepressants in depression was not impacted by recreational cannabis policy change. Together, these findings may reflect little substitution for these classes in the first few years after cannabis policy enactment.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798728230670Subjects--Topical Terms:

671705
Law.
Subjects--Index Terms:

CannabisIndex Terms--Genre/Form:

554714
Electronic books.

Cannabis Substitution for Prescription Drugs : = Understanding Longitudinal Trends in the Era of Legal Cannabis.
LDR:03472ntm a22003977 4500 001 1149440
005 20241022112056.5
006 m o d
007 cr bn ---uuuuu
008 250605s2021 xx obm 000 0 eng d
020 $a 9798728230670
035 $a (MiAaPQ)AAI28412290
035 $a AAI28412290
040 $a MiAaPQ $b eng $c MiAaPQ $d NTU
100 1 $a Strand, Lauren. $3 1475677
245 1 0 $a Cannabis Substitution for Prescription Drugs : $b Understanding Longitudinal Trends in the Era of Legal Cannabis.
264 0 $c 2021
300 $a 1 online resource (161 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Dissertations Abstracts International, Volume: 82-11, Section: B.
500 $a Advisor: Hansen, Ryan.
502 $a Thesis (Ph.D.)--University of Washington, 2021.
504 $a Includes bibliographical references
520 $a The effects of changes in cannabis laws continue to be of great interest to researchers, medical professionals, and policymakers as individual US states implement legal cannabis markets and cannabinoids are better studied. Cannabis may serve as a substitute for a number of substances including several classes of prescription drugs. In order to evaluate cannabis-for-prescription drug substitution in the period following legal dispensary opening in Washington State (July 2014-December 2017), we evaluated the effect of increased cannabis demand on opioid dispensing outcomes in individual counties. We instrumented county-quarter level cannabis sales using state-regulated dispensary density, estimating within-county changes in the number of individuals dispensed opioids per quarter. Effects of increasing retail cannabis sales on short- and long-term dispensing were small in magnitude and not statistically significant. Small effects for long-term high dose dispensing (approximately 3% of dispensing) may reflect substitution among the individuals at the highest risk for opioid use disorder; however, we did not find consistent evidence for substitution in the early period during recreational cannabis rollout in Washington. We also evaluated post-cannabis policy change substitution effects for antianxiety and antidepressant medication use in their respective indications among individuals with employer-sponsored insurance within US states (2010-2017). Medical cannabis policy did not lead to measurable changes in the level of use of antianxiety medications or antidepressants within their respective conditions; however, there may be noteworthy state and time-related heterogeneity as evidenced in event studies. In synthetic control models for Colorado and Washington, which legalized recreational cannabis in 2012, the use of antianxiety medications in anxiety and antidepressants in depression was not impacted by recreational cannabis policy change. Together, these findings may reflect little substitution for these classes in the first few years after cannabis policy enactment.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2024
538 $a Mode of access: World Wide Web
650 4 $a Law. $3 671705
650 4 $a Pharmaceutical sciences. $3 1180569
653 $a Cannabis
653 $a Claims
653 $a Medication
653 $a Opioid
653 $a Policy
653 $a Substitution
655 7 $a Electronic books. $2 local $3 554714
690 $a 0398
690 $a 0572
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a University of Washington. $b Pharmacy. $3 1475678
773 0 $t Dissertations Abstracts International $g 82-11B.
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28412290 $z click for full text (PQDT)