國立虎尾科技大學 |

Oral Prevalence of Akkermancia muciniphila Among Pediatric and Adult Orthodontic and Non-Orthodontic Patients.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Oral Prevalence of Akkermancia muciniphila Among Pediatric and Adult Orthodontic and Non-Orthodontic Patients./
Author:	Shen, Ching.
Description:	1 online resource (59 pages)
Notes:	Source: Masters Abstracts International, Volume: 85-03.
Contained By:	Masters Abstracts International85-03.
Subject:	Microbiology. -
Online resource:	click for full text (PQDT)
ISBN:	9798380343893

Oral Prevalence of Akkermancia muciniphila Among Pediatric and Adult Orthodontic and Non-Orthodontic Patients.
Shen, Ching.

Oral Prevalence of Akkermancia muciniphila Among Pediatric and Adult Orthodontic and Non-Orthodontic Patients. - 1 online resource (59 pages)

Source: Masters Abstracts International, Volume: 85-03.

Thesis (M.S.)--University of Nevada, Las Vegas, 2023.

Includes bibliographical references

Akkermansia muciniphila (AM) is one of many highly abundant intestinal microbes that influences homeostasis and metabolic disorders and may also play a role in oral disorders. However, there is little evidence regarding the oral prevalence of this organism. Based upon this lack of evidence, the primary goal of this project is to survey an existing saliva repository to determine the overall prevalence of this organism and any associations with demographic or patient characteristics (age, sex, body mass index, race/ethnicity, orthodontic therapy). Using an approved protocol, a total n = 141 pediatric samples from an existing saliva repository were screened using qPCR revealing 29.8% harbored AM with nearly equal distribution among males and females, p = 0.8347. Significantly higher percentages of pediatric, non-orthodontic patients were positive for AM (42.3%) compared with age-matched orthodontic patients (14.3%)-which were equally distributed among non-orthodontic males (42.1%) and non-orthodontic females (42.5%). In addition, analysis of the adult samples revealed that nearly equal percentages of males (18.2%) and females (16.7%) harbored detectable levels of salivary AM, p = 0.2035. However, a higher proportion of non-orthodontic adult samples harbored AM (21.3%) compared to orthodontic samples (12.8%, p = 0.0001), which was equally distributed among males and females. These results suggest that both age and the presence of orthodontic brackets may influence microbial composition and, more specifically, are associated with reduction in AM among both pediatric and adult populations from their baseline levels.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798380343893Subjects--Topical Terms:

591510
Microbiology.
Subjects--Index Terms:

Akkermansia muciniphilaIndex Terms--Genre/Form:

554714
Electronic books.

Oral Prevalence of Akkermancia muciniphila Among Pediatric and Adult Orthodontic and Non-Orthodontic Patients.
LDR:02984ntm a22003737 4500 001 1152579
005 20241209114601.5
006 m o d
007 cr mn ---uuuuu
008 250605s2023 xx obm 000 0 eng d
020 $a 9798380343893
035 $a (MiAaPQ)AAI30489108
035 $a AAI30489108
040 $a MiAaPQ $b eng $c MiAaPQ $d NTU
100 1 $a Shen, Ching. $3 671375
245 1 0 $a Oral Prevalence of Akkermancia muciniphila Among Pediatric and Adult Orthodontic and Non-Orthodontic Patients.
264 0 $c 2023
300 $a 1 online resource (59 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Masters Abstracts International, Volume: 85-03.
500 $a Advisor: Kingsley, Karl.
502 $a Thesis (M.S.)--University of Nevada, Las Vegas, 2023.
504 $a Includes bibliographical references
520 $a Akkermansia muciniphila (AM) is one of many highly abundant intestinal microbes that influences homeostasis and metabolic disorders and may also play a role in oral disorders. However, there is little evidence regarding the oral prevalence of this organism. Based upon this lack of evidence, the primary goal of this project is to survey an existing saliva repository to determine the overall prevalence of this organism and any associations with demographic or patient characteristics (age, sex, body mass index, race/ethnicity, orthodontic therapy). Using an approved protocol, a total n = 141 pediatric samples from an existing saliva repository were screened using qPCR revealing 29.8% harbored AM with nearly equal distribution among males and females, p = 0.8347. Significantly higher percentages of pediatric, non-orthodontic patients were positive for AM (42.3%) compared with age-matched orthodontic patients (14.3%)-which were equally distributed among non-orthodontic males (42.1%) and non-orthodontic females (42.5%). In addition, analysis of the adult samples revealed that nearly equal percentages of males (18.2%) and females (16.7%) harbored detectable levels of salivary AM, p = 0.2035. However, a higher proportion of non-orthodontic adult samples harbored AM (21.3%) compared to orthodontic samples (12.8%, p = 0.0001), which was equally distributed among males and females. These results suggest that both age and the presence of orthodontic brackets may influence microbial composition and, more specifically, are associated with reduction in AM among both pediatric and adult populations from their baseline levels.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2024
538 $a Mode of access: World Wide Web
650 4 $a Microbiology. $3 591510
650 4 $a Dentistry. $3 674038
653 $a Akkermansia muciniphila
653 $a Oral prevalence
653 $a Orthodontic patients
653 $a Saliva screening
655 7 $a Electronic books. $2 local $3 554714
690 $a 0410
690 $a 0567
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a University of Nevada, Las Vegas. $b School of Dental Medicine. $3 1479614
773 0 $t Masters Abstracts International $g 85-03.
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=30489108 $z click for full text (PQDT)