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Dispersity, structure and phase changes of proteins and bio agglomerates in biotechnological processes

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Dispersity, structure and phase changes of proteins and bio agglomerates in biotechnological processes/ edited by Arno Kwade, Ingo Kampen.
other author:	Kwade, Arno.
Published:	Cham :Springer Nature Switzerland : : 2024.,
Description:	ix, 547 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer Nature eBook
Subject:	Proteins - Biotechnology. -
Online resource:	https://doi.org/10.1007/978-3-031-63164-1
ISBN:	9783031631641

Dispersity, structure and phase changes of proteins and bio agglomerates in biotechnological processes
Dispersity, structure and phase changes of proteins and bio agglomerates in biotechnological processes[electronic resource] /edited by Arno Kwade, Ingo Kampen. - Cham :Springer Nature Switzerland :2024. - ix, 547 p. :ill. (some col.), digital ;24 cm.

1. Correlation of structure and properties of enzyme crystals in consideration of downstream processing and formulation -- 2. Multiscale Model-Based Investigation of Functional Macromolecular Agglomerates for Biotechnological Applications -- 3. Modeling-based Monitoring and Control of Protein Crystallization in Bioprocesses -- 4. Changes in structure, dispersity and phase behavior of proteins: The virus-like particles in the presence of nucleic acids.

This book serves as a comprehensive summary of the priority program SPP 1934, which focused on understanding the dispersity, structure, and phase changes of proteins and bio-agglomerates in biotechnological processes. Through contributions from various research groups, the program explored how sensitive proteins and bio-agglomerates are affected by the process environment during fermentation, downstream processing, and formulation. It investigated these effects across three size scales: microscale, encompassing single proteins, clusters, crystals, and virus-like particles; mesoscale, focusing on cells and cell clusters; and macroscale, examining overall process dynamics. The main objective was to enhance biotechnological process chains by elucidating the mechanical, thermal, and chemical stresses that impact protein and bio-agglomerate structures. By gaining insights into these stressors, the program aimed to enable precise control measures to mitigate denaturation and unfavorable growth of proteins and cells. This compilation seeks to contribute to the optimization of biotechnological processes, facilitating advancements in various industries.

ISBN: 9783031631641

Standard No.: 10.1007/978-3-031-63164-1doiSubjects--Topical Terms:

581486
Proteins
--Biotechnology.

LC Class. No.: TP248.65.P76

Dewey Class. No.: 660.63

Dispersity, structure and phase changes of proteins and bio agglomerates in biotechnological processes
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