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Nanotechnology in drug discovery

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Nanotechnology in drug discovery/ authored by Laksiri Weerasinghe, Imalka Munaweera & Senuri Kumarage.
Author:	Weerasinghe, Laksiri.
other author:	Munaweera, Imalka.
Published:	Singapore :Bentham Science Publishers, : 2024.,
Description:	1 online resource (222 p.) :col. ill. :
Subject:	Nanotechnology. -
Online resource:	https://www.eurekaselect.com/ebook_volume/3730
ISBN:	9789815238815

Nanotechnology in drug discovery
Weerasinghe, Laksiri.

Nanotechnology in drug discovery[electronic resource] /authored by Laksiri Weerasinghe, Imalka Munaweera & Senuri Kumarage. - 1st ed. - Singapore :Bentham Science Publishers,2024. - 1 online resource (222 p.) :col. ill.

Includes bibliographical references and index.

Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Preface -- Fundamentals of Nanotechnology -- 1. INTRODUCTION TO NANOMATERIALS -- 1.1. Changes in Thermal Properties -- 1.2. Changes in Optical Properties -- 1.3. Changes in Electronic Properties -- 1.4. Changes in Electrical Properties -- 1.5. Changes in Magnetic Properties -- 1.6. Changes in Chemical Properties -- 2. SYNTHESIS AND CHARACTERIZATION METHODS OF NANOMATERIALS -- 2.1. Bottom-up Synthesis Methods -- 2.1.1. Chemical Vapour Deposition -- 2.1.2. Physical Vapour Deposition -- 2.1.3. Thermal Decomposition -- 2.1.4. Chemical Reduction -- 2.1.5. Photo-reduction -- 2.1.6. Biological Synthesis -- 2.1.7. Solvothermal -- 2.1.8. Sol-gel -- 2.1.9. Co-precipitation -- 2.2. Top-down Synthesis Methods -- 2.2.1. Mechanical Ball Milling -- 2.2.2. Nanolithography -- 2.2.3. Laser Ablation -- 2.2.4. Electrospinning -- 2.3. Characterisation of Nanomaterials -- 3. NANODEVICES -- 3.1. Atomic Force Microscopy -- 3.2. Nanoarrays/nanochips -- 3.3. Nanofluidics -- 3.4. Nano Biosensors -- 3.5. Nanobiopsy -- 4. ADVANTAGES OF EMPLOYING NANOMATERIALS AND NANODEVICES IN DRUG DISCOVERY -- 5. CHALLENGES AND OPPORTUNITIES IN NANOSCALE -- 5.1. Challenges -- 5.2. Opportunities -- CONCLUSION -- PRACTICE QUESTIONS -- REFERENCES -- Nanotechnology in Drug Development -- Development of Nanomaterials as Drug Candidates -- 1. INTRODUCTION -- 2. DENDRIMERS -- 3. CARBON BASED NANOPARTICLES -- 3.1. Carbon Nanotubes -- 3.2. Fullerenes -- 3.3. Graphene Oxide and Derivatives -- 3.4. Carbon Quantum Dots -- 4. NANOHYDROGEL -- 5. PEPTIDE NANOSTRUCTURES -- 6. MXENES -- 7. SILICENE -- 8. ANTIMONENE -- CONCLUSION -- PRACTICE QUESTIONS -- REFERENCES -- Nanotechnology for Drug Design and Drug Delivery -- 1. INTRODUCTION -- 2. ATTRIBUTES OF AN EFFECTIVE DELIVERY SYSTEM -- 3. UP-TO-DATE DRUG DELIVERY SYSTEMS.

This book provides a compressive overview of nanotechnology in modern drug discovery for students and researchers. The book starts with the fundamentals of nanotechnology followed by nanomaterials in pharmaceutical drug design drug delivery applications regulatory aspects formulation and nanoparticle biotransformation. It provides a step by step guide through the drug development process while conveying information about the benefits of nanomaterials for therapy. The book concludes with perspective on the future of nanotechnologybased drug discovery summarizing current knowledge on nanotherapeutics and translational medicine. Key Features Explains the fundamentals of nanotechnology in drug discovery Includes uptodate information on modern nanopharmaceutical manufacturing nanomaterials and nanoparticlebased drug therapy Practice questions for learners and a list of references for advanced readers for each chapter

ISBN: 9789815238815Subjects--Topical Terms:

557660
Nanotechnology.

LC Class. No.: T174.7 / .W447 2024

Dewey Class. No.: 620.5

Nanotechnology in drug discovery
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245 1 0 $a Nanotechnology in drug discovery $h [electronic resource] / $c authored by Laksiri Weerasinghe, Imalka Munaweera & Senuri Kumarage.
250 $a 1st ed.
260 $a Singapore : $b Bentham Science Publishers, $c 2024.
300 $a 1 online resource (222 p.) : $b col. ill.
504 $a Includes bibliographical references and index.
505 0 $a Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Preface -- Fundamentals of Nanotechnology -- 1. INTRODUCTION TO NANOMATERIALS -- 1.1. Changes in Thermal Properties -- 1.2. Changes in Optical Properties -- 1.3. Changes in Electronic Properties -- 1.4. Changes in Electrical Properties -- 1.5. Changes in Magnetic Properties -- 1.6. Changes in Chemical Properties -- 2. SYNTHESIS AND CHARACTERIZATION METHODS OF NANOMATERIALS -- 2.1. Bottom-up Synthesis Methods -- 2.1.1. Chemical Vapour Deposition -- 2.1.2. Physical Vapour Deposition -- 2.1.3. Thermal Decomposition -- 2.1.4. Chemical Reduction -- 2.1.5. Photo-reduction -- 2.1.6. Biological Synthesis -- 2.1.7. Solvothermal -- 2.1.8. Sol-gel -- 2.1.9. Co-precipitation -- 2.2. Top-down Synthesis Methods -- 2.2.1. Mechanical Ball Milling -- 2.2.2. Nanolithography -- 2.2.3. Laser Ablation -- 2.2.4. Electrospinning -- 2.3. Characterisation of Nanomaterials -- 3. NANODEVICES -- 3.1. Atomic Force Microscopy -- 3.2. Nanoarrays/nanochips -- 3.3. Nanofluidics -- 3.4. Nano Biosensors -- 3.5. Nanobiopsy -- 4. ADVANTAGES OF EMPLOYING NANOMATERIALS AND NANODEVICES IN DRUG DISCOVERY -- 5. CHALLENGES AND OPPORTUNITIES IN NANOSCALE -- 5.1. Challenges -- 5.2. Opportunities -- CONCLUSION -- PRACTICE QUESTIONS -- REFERENCES -- Nanotechnology in Drug Development -- Development of Nanomaterials as Drug Candidates -- 1. INTRODUCTION -- 2. DENDRIMERS -- 3. CARBON BASED NANOPARTICLES -- 3.1. Carbon Nanotubes -- 3.2. Fullerenes -- 3.3. Graphene Oxide and Derivatives -- 3.4. Carbon Quantum Dots -- 4. NANOHYDROGEL -- 5. PEPTIDE NANOSTRUCTURES -- 6. MXENES -- 7. SILICENE -- 8. ANTIMONENE -- CONCLUSION -- PRACTICE QUESTIONS -- REFERENCES -- Nanotechnology for Drug Design and Drug Delivery -- 1. INTRODUCTION -- 2. ATTRIBUTES OF AN EFFECTIVE DELIVERY SYSTEM -- 3. UP-TO-DATE DRUG DELIVERY SYSTEMS.
505 8 $a 3.1. Liposomes -- 3.2. Polymeric Micelles -- 3.3. Nanogels -- 3.4. Nanoemulsions -- 3.5. Solid Lipid Nanoparticles -- 3.6. Dendrimers -- 3.7. Inorganic Nanoparticles -- 3.8. Electrospun Polymeric Nanofiber -- CONCLUSION -- PRACTICE QUESTIONS -- REFERENCES -- Fate of Nanoparticles -- 1. INTRODUCTION -- 2. CELL UPTAKE AND METABOLISM -- 2.1. Endocytosis -- 2.1.1. Clathrin-mediated Endocytosis -- 2.1.2. Caveolin-dependent Endocytosis -- 2.1.3. Clathrin and Caveolin-independent Endocytosis -- 2.1.4. Phagocytosis -- 2.1.5. Macropinocytosis -- 2.2. Direct Fusion with the Plasma Membrane -- 2.2.1. Cytoplasmic Entry by Direct Translocation -- 2.2.2. Cytoplasmic Entry by Lipid Fusion -- 2.2.3. Electroporation -- CONCLUSION -- PRACTICE QUESTIONS -- REFERENCES -- Regulation, Development, and Commercialization of Nano-Based Drugs -- 1. INTRODUCTION -- CONCLUSION -- REFERENCES -- Future of Nanotechnology-Based Drug Discovery -- 1. INTRODUCTION -- 2. FUTURE OF NANOTECHNOLOGY IN DISEASE DIAGNOSIS AND THERAPY -- 3. PATIENT FOLLOW-UP AFTER TREATMENTS -- 4. NANOTECHNOLOGY IN OVERCOMING CANCER DRUG RESISTANCE -- 5. TRANSLATION OF NANOMEDICINE INTO SOLID DOSAGES -- CONCLUSION -- REFERENCES -- Subject Index -- Back Cover.
520 $a This book provides a compressive overview of nanotechnology in modern drug discovery for students and researchers. The book starts with the fundamentals of nanotechnology followed by nanomaterials in pharmaceutical drug design drug delivery applications regulatory aspects formulation and nanoparticle biotransformation. It provides a step by step guide through the drug development process while conveying information about the benefits of nanomaterials for therapy. The book concludes with perspective on the future of nanotechnologybased drug discovery summarizing current knowledge on nanotherapeutics and translational medicine. Key Features Explains the fundamentals of nanotechnology in drug discovery Includes uptodate information on modern nanopharmaceutical manufacturing nanomaterials and nanoparticlebased drug therapy Practice questions for learners and a list of references for advanced readers for each chapter
588 $a Description based on print version record.
650 0 $a Nanotechnology. $3 557660
650 0 $a Drug development. $3 581824
700 1 $a Munaweera, Imalka. $3 1451863
700 1 $a Kumarage, Senuri. $3 1497439
856 4 0 $u https://www.eurekaselect.com/ebook_volume/3730