國立虎尾科技大學 |

Handbook of process chromatography = development, manufacturing, validation and economics.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Handbook of process chromatography/
其他題名:	development, manufacturing, validation and economics.
作者:	Hagel, Lars.
其他作者:	Sofer, G. K.
出版者:	London ;Academic, : 2008.,
面頁冊數:	xvi, 363 p. :ill. ; : 24 cm. +; 1 CD-ROM. +
附註:	Previous ed.: published as by G.K. Sofer and Lars Hagel. 1997.
標題:	Chromatographic analysis - Industrial applications. -
電子資源:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780123740236

Handbook of process chromatography = development, manufacturing, validation and economics.
Hagel, Lars.

Handbook of process chromatographydevelopment, manufacturing, validation and economics.[electronic resource] : - 2nd ed. / - London ;Academic,2008. - xvi, 363 p. :ill. ;24 cm. +1 CD-ROM.

Previous ed.: published as by G.K. Sofer and Lars Hagel. 1997.

Includes bibliographical references and index.

Preface -- Acknowledgements -- 1. Biopharmaceuticals Today -- 2. Process Capability and Production Scenarios -- 3. Process Design Concepts -- 4. Separation Technologies -- 5. Analysis -- 6. Cleaning and Sanitization -- 7. Validation -- 8. Economics -- 9. Basic Properties of Peptides, Proteons, Nucleic Acids, and Virus Particles -- 10. Optimization of Chromatographic Separations -- 11. Equipment -- 12. Column Packing -- Appendix A. Symbols and Definitions in Liquid Chromatography -- Appendix B. Dimensionless Numbers -- Appendix C. Activities for Biopharmaceutical Production from Genetically Engineered Mammalian Cells -- Appendix D. Simulations Using the Supplied Software.

This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purification unit operations. This book will tie that experience together for the next generation of readers. Updates include: - sources and productivity - types of products made today - experiences in clinical and licensed products - economics - current status of validation - illustrations and tables - automated column packing - automated systems New topics include: - the use of disposables - multiproduct versus dedicated production - design principles for chromatography media and filters - ultrafiltration principles and optimization - risk assessments - characterization studies - design space - platform technologies - process analytical technologies (PATs) - biogenerics - comparability assessments Key Features: - new approaches to process optimiaztion - use of patform technologies - applying risk assessment to process design.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2008.

Mode of access: World Wide Web.

ISBN: 9780123740236

Source: 139276:139413Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

655191
Chromatographic analysis
--Industrial applications.Index Terms--Genre/Form:

554714
Electronic books.

LC Class. No.: QD79.C4 / H34 2008eb

Dewey Class. No.: 543.8

Handbook of process chromatography = development, manufacturing, validation and economics.
LDR:03374nam 2200361Ia 4500 001 618218
003 OCoLC
005 20090612093507.0
006 m d
007 cr cn|||||||||
008 100106s2008 enka sb 001 0 eng d
020 $a 9780123740236
020 $a 0123740231
029 1 $a NZ1 $b 12541529
029 1 $a AU@ $b 000043178384
035 $a (OCoLC)228148496
035 $a ocn228148496
037 $a 139276:139413 $b Elsevier Science & Technology $n http://www.sciencedirect.com
040 $a OPELS $c OPELS
049 $a TEFA
050 1 4 $a QD79.C4 $b H34 2008eb
082 0 4 $a 543.8 $2 22
100 1 $a Hagel, Lars. $3 655190
245 1 0 $a Handbook of process chromatography $h [electronic resource] : $b development, manufacturing, validation and economics.
250 $a 2nd ed. / $b Lars Hagel, G�unter Jagschies and Gail Sofer.
260 $a London ; $a Burlington, MA : $c 2008. $b Academic,
300 $a xvi, 363 p. : $b ill. ; $c 24 cm. + $e 1 CD-ROM.
500 $a Previous ed.: published as by G.K. Sofer and Lars Hagel. 1997.
500 $a Includes CD-ROM.
504 $a Includes bibliographical references and index.
505 0 $a Preface -- Acknowledgements -- 1. Biopharmaceuticals Today -- 2. Process Capability and Production Scenarios -- 3. Process Design Concepts -- 4. Separation Technologies -- 5. Analysis -- 6. Cleaning and Sanitization -- 7. Validation -- 8. Economics -- 9. Basic Properties of Peptides, Proteons, Nucleic Acids, and Virus Particles -- 10. Optimization of Chromatographic Separations -- 11. Equipment -- 12. Column Packing -- Appendix A. Symbols and Definitions in Liquid Chromatography -- Appendix B. Dimensionless Numbers -- Appendix C. Activities for Biopharmaceutical Production from Genetically Engineered Mammalian Cells -- Appendix D. Simulations Using the Supplied Software.
520 $a This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purification unit operations. This book will tie that experience together for the next generation of readers. Updates include: - sources and productivity - types of products made today - experiences in clinical and licensed products - economics - current status of validation - illustrations and tables - automated column packing - automated systems New topics include: - the use of disposables - multiproduct versus dedicated production - design principles for chromatography media and filters - ultrafiltration principles and optimization - risk assessments - characterization studies - design space - platform technologies - process analytical technologies (PATs) - biogenerics - comparability assessments Key Features: - new approaches to process optimiaztion - use of patform technologies - applying risk assessment to process design.
533 $a Electronic reproduction. $b Amsterdam : $c Elsevier Science & Technology, $d 2008. $n Mode of access: World Wide Web. $n System requirements: Web browser. $n Title from title screen (viewed on May 14, 2008). $n Access may be restricted to users at subscribing institutions.
650 0 $a Chromatographic analysis $x Industrial applications. $3 655191
655 7 $a Electronic books. $2 local $3 554714
700 1 $a Sofer, G. K. $3 583538
700 1 $a Jagschies, G�unter. $3 655192
710 2 $a ScienceDirect (Online service) $3 636041
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780123740236 $z An electronic book accessible through the World Wide Web; click for information
994 $a C0 $b TEF