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Measuring immunity = basic biology and clinical assessment /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Measuring immunity/ edited by Michael T. Lotze and Angus W. Thomson.
其他題名:	basic biology and clinical assessment /
作者:	Lotze, Michael T.
其他作者:	Thomson, Angus W.
出版者:	San Diego, Calif. ;Elsevier Academic Press, : c2005.,
面頁冊數:	xix, 722 p. :ill. ; : 29 cm.;
標題:	Immunity. -
電子資源:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780124559004

Measuring immunity = basic biology and clinical assessment /
Lotze, Michael T.

Measuring immunitybasic biology and clinical assessment /[electronic resource] :edited by Michael T. Lotze and Angus W. Thomson. - San Diego, Calif. ;Elsevier Academic Press,c2005. - xix, 722 p. :ill. ;29 cm.

Includes bibliographical references and index.

Introduction -- Preface -- FUNDAMENTALS OF THE IMMMUNE RESPONSE -- MHC Class I -- MHC Class II -- Cytokine receptor heterogeneity -- Measuring cytokine polymorphisms: functional variations and disease associations -- Signaling molecules affecting immune response -- Toll like receptors in innate immunity -- DNA sequence-specific transcription factors -- Genetic factors diversity in NK and NKT cells -- SEROLOGIC ASSAYS -- Handling sera and obtaining fluid from different compartments practical considerations -- Acute- phase proteins and inflammation: immunological and clinical implications, Complement in health and disease -- Immunoglobulin titers and immunoglobulin subtypes -- Human antiglobulin responses -- Measuring Rheumatoid Factors -- Autoantibodies -- Measuring antibody affinity using fluorescence -- SLE associated tests -- Multiplexed serum assays -- CELLULAR ENUMERATION AND PHENOTYPING -- Handling and storage of cells and sera: practical considerations -- Phenotypic and functional measurements on circulating immune cells and their subsets -- Natural Killer cells -- Tetramer Analysis -- Peripheral blood naive and memory B cells -- Dendritic cells -- Monocytes and macrophages -- Tumor cells -- Intracellular cytokine assays -- CELLULAR FUNCTION AND PHYSIOLOGY -- Cytolytic assays -- Mixed leukocyte reactions -- Antigen/mitogen-stimulated lymphocyte proliferation -- Monitoring cell death -- Cytokine enzyme linked immunosorbent spot (ELISPOT) assay -- Testing natural killer cells -- PROVOCATIVE ASSAYS in vivo -- Delayed type hypersensitivity responses -- Rebuck windows: granulocyte function -- The vascular and coagulation systems -- Sentinel node assays -- Imaging inflammation -- ASSAYS IN ACUTE AND CHRONIC DISEASES -- Cancersolid tumors -- Cancerhematologic disorders -- Autoimmunitytype 1 diabetes -- Autoimmunitysystemic lupus erythematosus -- Autoimmunitymultiple sclerosis -- Autoimmunitygastrointestinal -- Autoimmunityendocrine -- AutoimmunityvasculitisTransplantation -- Viral responsesHIV 1 -- Viral responsesEpstein- Barr virus -- Viral responseshepatitis -- Dermatology -- Atherosclerosis -- Primary immunodeficiencies -- Asthma and allergy -- NEW TECHNOLOGIES -- Cerum proteomic profiling and analysis -- Imaging cytometry -- Cancer biometrics -- Genomics and microarrays -- Image informatics -- INDEX of manufacturers and suppliers, addresses, web site.

Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology. * Defines which assays of immune function are helpful in the assessment of clinical disorders involving inflammation and immunity * Assesses the dynamics of cellular and soluble factors in the peripheral blood using modern techniques * Includes basic science foundations as well as the approaches currently applied.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2007.

Mode of access: World Wide Web.

ISBN: 9780124559004

Source: 98491:98494Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

581467
Immunity.
Index Terms--Genre/Form:

554714
Electronic books.

LC Class. No.: QR181 / .L6 2005eb

Dewey Class. No.: 616.079

National Library of Medicine Call No.: 2005 B-924

Measuring immunity = basic biology and clinical assessment /
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245 1 0 $a Measuring immunity $h [electronic resource] : $b basic biology and clinical assessment / $c edited by Michael T. Lotze and Angus W. Thomson.
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300 $a xix, 722 p. : $b ill. ; $c 29 cm.
504 $a Includes bibliographical references and index.
505 0 $a Introduction -- Preface -- FUNDAMENTALS OF THE IMMMUNE RESPONSE -- MHC Class I -- MHC Class II -- Cytokine receptor heterogeneity -- Measuring cytokine polymorphisms: functional variations and disease associations -- Signaling molecules affecting immune response -- Toll like receptors in innate immunity -- DNA sequence-specific transcription factors -- Genetic factors diversity in NK and NKT cells -- SEROLOGIC ASSAYS -- Handling sera and obtaining fluid from different compartments practical considerations -- Acute- phase proteins and inflammation: immunological and clinical implications, Complement in health and disease -- Immunoglobulin titers and immunoglobulin subtypes -- Human antiglobulin responses -- Measuring Rheumatoid Factors -- Autoantibodies -- Measuring antibody affinity using fluorescence -- SLE associated tests -- Multiplexed serum assays -- CELLULAR ENUMERATION AND PHENOTYPING -- Handling and storage of cells and sera: practical considerations -- Phenotypic and functional measurements on circulating immune cells and their subsets -- Natural Killer cells -- Tetramer Analysis -- Peripheral blood naive and memory B cells -- Dendritic cells -- Monocytes and macrophages -- Tumor cells -- Intracellular cytokine assays -- CELLULAR FUNCTION AND PHYSIOLOGY -- Cytolytic assays -- Mixed leukocyte reactions -- Antigen/mitogen-stimulated lymphocyte proliferation -- Monitoring cell death -- Cytokine enzyme linked immunosorbent spot (ELISPOT) assay -- Testing natural killer cells -- PROVOCATIVE ASSAYS in vivo -- Delayed type hypersensitivity responses -- Rebuck windows: granulocyte function -- The vascular and coagulation systems -- Sentinel node assays -- Imaging inflammation -- ASSAYS IN ACUTE AND CHRONIC DISEASES -- Cancersolid tumors -- Cancerhematologic disorders -- Autoimmunitytype 1 diabetes -- Autoimmunitysystemic lupus erythematosus -- Autoimmunitymultiple sclerosis -- Autoimmunitygastrointestinal -- Autoimmunityendocrine -- AutoimmunityvasculitisTransplantation -- Viral responsesHIV 1 -- Viral responsesEpstein- Barr virus -- Viral responseshepatitis -- Dermatology -- Atherosclerosis -- Primary immunodeficiencies -- Asthma and allergy -- NEW TECHNOLOGIES -- Cerum proteomic profiling and analysis -- Imaging cytometry -- Cancer biometrics -- Genomics and microarrays -- Image informatics -- INDEX of manufacturers and suppliers, addresses, web site.
505 0 $a MHC class I -- MHC class II -- Cytokine receptor heterogeneity -- Genetic diversity at human cytokine loci in health and disease -- Signaling molecules affecting immune response -- Toll-like receptors in innate immunity -- DNA sequence-specific transcription factors -- Genetic diversity in NK and NKT cells -- Handling sera and obtaining fluid from different compartments -- Acute-phase proteins and inflammation -- Complement in health and disease -- Immunoglobulin titers and immunoglobulin subtypes -- Human antiglobulin responses -- Rheumatoid factors -- Autoantibodies -- Antibody affinity using fluorescence -- SLE-associated tests -- Multiplexed serum assays -- Handling and storage of cells and sera: practical considerations -- Phenotypic and functional measurements on circulating immune cells and their subsets -- Natural killer cells -- Tetramer analysis -- Peripheral blood naive and memory B cells -- Dendritic cells -- Monocytes and macrophages -- Tumor cells -- Regulatory T cells -- Intracellular cytokine assays -- Cytolytic assays --
505 0 $a Mixed leukocyte reactions -- Antigen/mitogen-stimulated lymphocyte proliferation -- Monitoring cell death -- Cytokine enzyme linked immunosorbent spot (ELISPOT) assay -- Testing natural killer cells -- Delayed type hypersensitivity responses -- Rebuck windows: granulocyte function -- The vascular and coagulation systems -- Sentinel node assays -- Imaging inflammation -- Cancer - solid tumors -- Cancer - hematologic disorders -- Autoimmunity - rheumatoid arthritis -- Autoimmunity - type 1 diabetes -- Autoimmunity - systemic lupus erythematosus -- Autoimmunity - multiple sclerosis -- Autoimmunity - inflammatory bowel disease -- Autoimmunity - endocrine -- Autoimmunity - vasculitis -- Transplantation -- Viral responses - HIV-1 -- Viral responses - epstein-barr virus -- Viral responses - hepatitis -- Dermatology -- Arteriosclerosis -- Primary immunodeficiencies -- Asthma and allergy -- Serum proteomic profiling and analysis -- Imaging cytometry -- Cancer biometrics -- Genomics and microarrays -- Image informatics.
520 $a Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology. * Defines which assays of immune function are helpful in the assessment of clinical disorders involving inflammation and immunity * Assesses the dynamics of cellular and soluble factors in the peripheral blood using modern techniques * Includes basic science foundations as well as the approaches currently applied.
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