Language:
English
繁體中文
Help
Login
Back
Switch To:
Labeled
|
MARC Mode
|
ISBD
Adenoviral vectors for gene therapy
~
Curiel, David.
Adenoviral vectors for gene therapy
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Adenoviral vectors for gene therapy/ edited by David T. Curiel, Joanne T. Douglas.
other author:
Curiel, David.
Published:
Amsterdam ;Academic Press, : c2002.,
Description:
1 online resource (xxviii, 677 p.) :ill. :
Subject:
Gene therapy. -
Online resource:
http://www.sciencedirect.com/science/book/9780121995041
ISBN:
9780121995041
Adenoviral vectors for gene therapy
Adenoviral vectors for gene therapy
[electronic resource] /edited by David T. Curiel, Joanne T. Douglas. - Amsterdam ;Academic Press,c2002. - 1 online resource (xxviii, 677 p.) :ill.
Includes bibliographical references.
Adenovirus Structure -- Biology of Adenovirus Cell Entry -- Adenovirus Replication -- Adenoviral Vector Construction I: Mammalian Systems -- Adenoviral Vector Construction II: Bacterial Systems -- Propagation of Adenoviral Vectors: Use of PER. C6 Cells -- Purification of Adenovirus -- Targeted Adenoviral Vectors I: Transductional Targeting -- Targeted Adenoviral Vectors II: Transcriptional Targeting -- Development of Attenuated Replication Competent Adenoviruses ARCAs) for the treatment of Prostate Cancer -- Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer -- Innate Immune Responses to in Vivo Adenovirus Infection -- Humoral Immune Response -- Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy -- High-Capacity "Gutless" Adenoviral Vectors: Technical Aspects and Applications -- Xenogenic Adenoviral Vectors -- Hybrid Adenoviral Vectors -- Utility of Adenoviral Vectors in Animal Models of Human Disease I: Cancer -- Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease -- Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases -- Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations -- Imaging Adenovirus-Medicated Gene Transfer.
Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors. Key Features * Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors * Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement * Demonstrates noninvasive imaging of adenovirus-mediated gene transfer * Discusses utility of adenoviral vectors in animal disease models * Considers Federal Drug Administration regulations for human clinical trials.
ISBN: 9780121995041
Source: 89480:89480Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:
582271
Gene therapy.
Index Terms--Genre/Form:
554714
Electronic books.
LC Class. No.: RB155.8 / .A34 2002eb
Dewey Class. No.: 616/.042
National Library of Medicine Call No.: 2002 H-966
Adenoviral vectors for gene therapy
LDR
:03831cam 2200421Ia 4500
001
690791
003
OCoLC
005
20111122085744.0
006
m d
007
cr cn|||||||||
008
120103s2002 ne a ob 000 0 eng d
019
$a
209861927
$a
648350089
020
$a
9780121995041
020
$a
0121995046
020
$a
9781435632004 (electronic bk.)
020
$a
1435632001 (electronic bk.)
029
1
$a
NZ1
$b
12432581
035
$a
(OCoLC)162129420
$z
(OCoLC)209861927
$z
(OCoLC)648350089
035
$a
ocn162129420
037
$a
89480:89480
$b
Elsevier Science & Technology
$n
http://www.sciencedirect.com
040
$a
OPELS
$b
eng
$c
OPELS
$d
OCLCQ
$d
N$T
$d
YDXCP
$d
E7B
$d
OCLCQ
049
$a
TEFA
050
4
$a
RB155.8
$b
.A34 2002eb
060
4
$a
2002 H-966
060
4
$a
QZ 50
$b
A2326 2002
072
7
$a
HEA
$x
039060
$2
bisacsh
072
7
$a
MED
$x
107000
$2
bisacsh
082
0 4
$a
616/.042
$2
22
245
0 0
$a
Adenoviral vectors for gene therapy
$h
[electronic resource] /
$c
edited by David T. Curiel, Joanne T. Douglas.
260
$a
Amsterdam ;
$a
Boston :
$b
Academic Press,
$c
c2002.
300
$a
1 online resource (xxviii, 677 p.) :
$b
ill.
504
$a
Includes bibliographical references.
505
0
$a
Adenovirus Structure -- Biology of Adenovirus Cell Entry -- Adenovirus Replication -- Adenoviral Vector Construction I: Mammalian Systems -- Adenoviral Vector Construction II: Bacterial Systems -- Propagation of Adenoviral Vectors: Use of PER. C6 Cells -- Purification of Adenovirus -- Targeted Adenoviral Vectors I: Transductional Targeting -- Targeted Adenoviral Vectors II: Transcriptional Targeting -- Development of Attenuated Replication Competent Adenoviruses ARCAs) for the treatment of Prostate Cancer -- Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer -- Innate Immune Responses to in Vivo Adenovirus Infection -- Humoral Immune Response -- Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy -- High-Capacity "Gutless" Adenoviral Vectors: Technical Aspects and Applications -- Xenogenic Adenoviral Vectors -- Hybrid Adenoviral Vectors -- Utility of Adenoviral Vectors in Animal Models of Human Disease I: Cancer -- Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease -- Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases -- Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations -- Imaging Adenovirus-Medicated Gene Transfer.
520
$a
Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors. Key Features * Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors * Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement * Demonstrates noninvasive imaging of adenovirus-mediated gene transfer * Discusses utility of adenoviral vectors in animal disease models * Considers Federal Drug Administration regulations for human clinical trials.
588
$a
Description based on print version record.
650
0
$a
Gene therapy.
$3
582271
650
0
$a
Adenoviruses.
$3
810748
650
1 2
$a
Gene Therapy
$x
methods.
$3
780596
650
2 2
$a
Adenoviridae.
$3
810749
650
2 2
$a
Genetic Vectors
$x
therapeutic use.
$3
810750
650
6
$a
Th�erapie g�enique.
$3
810751
650
6
$a
Ad�enovirus.
$3
810752
650
7
$a
HEALTH & FITNESS
$x
Diseases
$x
Genetic.
$2
bisacsh
$3
788733
650
7
$a
MEDICAL
$x
Genetics.
$2
bisacsh
$3
788734
650
7
$a
Adenov�irus.
$2
larpcal
$3
810753
650
7
$a
Genes virais.
$2
larpcal
$3
810754
650
7
$a
V�irus de dna.
$2
larpcal
$3
810755
655
4
$a
Electronic books.
$2
local
$3
554714
700
1
$a
Curiel, David.
$3
810747
700
1
$a
Douglas, Joanne T.
$3
676436
856
4 0
$3
ScienceDirect
$u
http://www.sciencedirect.com/science/book/9780121995041
938
$a
YBP Library Services
$b
YANK
$n
2783945
938
$a
ebrary
$b
EBRY
$n
ebr10216805
994
$a
C0
$b
TEF
based on 0 review(s)
Multimedia
Reviews
Add a review
and share your thoughts with other readers
Export
pickup library
Processing
...
Change password
Login