國立虎尾科技大學 |

3D cell-based biosensors in drug discovery programs = microtissue engineering for high throughput screening /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	3D cell-based biosensors in drug discovery programs/ William S. Kisaalita.
Reminder of title:	microtissue engineering for high throughput screening /
Author:	Kisaalita, William Ssempa,
Published:	Boca Raton [Fla.] :CRC Press, : 2010.,
Description:	466 p.
Subject:	Pharmaceutical biotechnology. -
Online resource:	Distributed by publisher. Purchase or institutional license may be required for access.
ISBN:	9781420073508 (e-book : PDF)

3D cell-based biosensors in drug discovery programs = microtissue engineering for high throughput screening /
Kisaalita, William Ssempa,1953-

3D cell-based biosensors in drug discovery programsmicrotissue engineering for high throughput screening /[electronic resource] :William S. Kisaalita. - Boca Raton [Fla.] :CRC Press,2010. - 466 p.

Includes bibliographical references and index.

(Publisher-supplied data) Biosensors and Bioassays -- Target-Driven Drug Discovery -- Comparative Genomics and Proteomics -- Comparative Structure and Function -- Chemical Microenvironmental Factors -- Spatial and Temporal Microenvironmental Factors -- Material Physical Property and Force Microenvironmental Factors -- Proteomics as a Promising Tool in the Search for 3D Biomarkers -- Readout Present and Near Future -- Ready-to-Use Commercial 3D Plates -- Challenges to Adopting 3D Cultures in HTS Programs -- Cases for 3D Cultures in Drug Discovery -- Ideal Case Study Design.

"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.

Mode of access: World Wide Web.

ISBN: 9781420073508 (e-book : PDF)Subjects--Topical Terms:

582896
Pharmaceutical biotechnology.
Index Terms--Genre/Form:

554714
Electronic books.

3D cell-based biosensors in drug discovery programs = microtissue engineering for high throughput screening /
LDR:02284nam 2200265Ia 4500 001 714765
003 FlBoTFG
005 20100929160852.0
006 a|||||s|||||||||||
007 cr||||
008 121120s2010 flu sb 001 0 eng d
020 $a 9781420073508 (e-book : PDF)
035 $a CRC00E73494PDF
040 $a FlBoTFG $c FlBoTFG
090 $a RS380 $b .K537 2010
092 $a 615.19 $b K614
100 1 $a Kisaalita, William Ssempa, $d 1953- $3 848070
245 1 0 $a 3D cell-based biosensors in drug discovery programs $h [electronic resource] : $b microtissue engineering for high throughput screening / $c William S. Kisaalita.
260 $a Boca Raton [Fla.] : $b CRC Press, $c 2010.
300 $a 466 p.
504 $a Includes bibliographical references and index.
505 8 $a (Publisher-supplied data) Biosensors and Bioassays -- Target-Driven Drug Discovery -- Comparative Genomics and Proteomics -- Comparative Structure and Function -- Chemical Microenvironmental Factors -- Spatial and Temporal Microenvironmental Factors -- Material Physical Property and Force Microenvironmental Factors -- Proteomics as a Promising Tool in the Search for 3D Biomarkers -- Readout Present and Near Future -- Ready-to-Use Commercial 3D Plates -- Challenges to Adopting 3D Cultures in HTS Programs -- Cases for 3D Cultures in Drug Discovery -- Ideal Case Study Design.
520 $a "This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.
530 $a Also available in print edition.
538 $a Mode of access: World Wide Web.
650 0 $a Pharmaceutical biotechnology. $3 582896
650 0 $a Biosensors. $3 555917
650 0 $a High throughput screening (Drug development) $3 582128
655 7 $a Electronic books. $2 local $3 554714
776 1 $z 9781420073492
856 4 0 $u http://marc.crcnetbase.com/isbn/9781420073508 $q application/PDF $z Distributed by publisher. Purchase or institutional license may be required for access.