國立虎尾科技大學 |

Proteases of infectious agents

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Proteases of infectious agents/ edited by Ben M. Dunn.
其他作者:	Dunn, Ben M.
出版者:	San Diego, Calif. :Academic, : c1999.,
面頁冊數:	1 online resource (xvii, 282 p., [15] p. of col. plates) :ill. (some col.) :
標題:	Proteolytic enzymes. -
電子資源:	http://www.sciencedirect.com/science/book/9780124205109
ISBN:	9780124205109

Proteases of infectious agents
Proteases of infectious agents[electronic resource] /edited by Ben M. Dunn. - San Diego, Calif. :Academic,c1999. - 1 online resource (xvii, 282 p., [15] p. of col. plates) :ill. (some col.)

J. Erickson and M. Eissenstat, HIV Protease as a Target for the Design of Antiviral Agents for AIDS. -- C. Steinkèuhler, A. Urbani, and R. De Francesco, Proteases of the Hepatitis C Virus. -- S. Abdel-Meguid and X. Qiu, Human Herpesvirus Proteases. -- C. Abad-Zapatero, R. Goldman, and K. Stewart, The Secreted Proteinases from Candida: Challenges for Structure-Aided Drug Design. -- M.N.G. James and E. Bergman, Proteolytic Enzymes of the Viruses of the Family Picornaviridae. -- C. Berry, Proteases as Drug Targets in the Treatment of Malaria. -- J. Cazzulo, Chagas Disease. -- H. Kido, Y. Chen, M. Murakami, Y. Beppu, and T. Towatari, Cellular Proteinases and Viral Infection: Influenza Virus, Sendai Virus, and HIV-1. -- M. Lively, Bacterial Type 1 Signal Peptidases. -- J.A. Garcia, M.R. Fernâandez-Fernâandez, and J.J. Lâopez-Moya, Proteinases Involved in Plant Virus Genome Expression. -- Subject Index.

Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery.

ISBN: 9780124205109

Source: 79195:79195Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

796650
Proteolytic enzymes.
Index Terms--Genre/Form:

554714
Electronic books.

LC Class. No.: QP609.P78 / P746 1999eb

Dewey Class. No.: 572/.76

National Agricultural Library Call No.: RC112 / .P76 1999

National Library of Medicine Call No.: 1999 F-117

Proteases of infectious agents
LDR:04504cam a2200421Ia 4500 001 727486
005 20120813085808.0
006 m d
007 cr cn|||||||||
008 130125s1999 cauaf ob 001 0 eng d
019 $a 742284441
020 $a 9780124205109
020 $a 0124205100
020 $a 9786611025113
020 $a 6611025111
029 1 $a NZ1 $b 12432358
029 1 $a AU@ $b 000048130384
029 1 $a DEBBG $b BV039830346
035 $a ocn162128877
037 $a 79195:79195 $b Elsevier Science & Technology $n http://www.sciencedirect.com
040 $a OPELS $b eng $c OPELS $d OCLCQ $d IDEBK $d OCLCQ
049 $a NTYA
050 4 $a QP609.P78 $b P746 1999eb
060 4 $a 1999 F-117
060 4 $a QU 136 $b P96715 1999
070 $a RC112 $b .P76 1999
072 0 $a X300
072 0 $a X380
072 7 $a MJCJ $2 bicssc
082 0 4 $a 572/.76 $2 22
245 0 0 $a Proteases of infectious agents $h [electronic resource] / $c edited by Ben M. Dunn.
260 $a San Diego, Calif. : $b Academic, $c c1999.
300 $a 1 online resource (xvii, 282 p., [15] p. of col. plates) : $b ill. (some col.)
505 0 $a J. Erickson and M. Eissenstat, HIV Protease as a Target for the Design of Antiviral Agents for AIDS. -- C. Steinkèuhler, A. Urbani, and R. De Francesco, Proteases of the Hepatitis C Virus. -- S. Abdel-Meguid and X. Qiu, Human Herpesvirus Proteases. -- C. Abad-Zapatero, R. Goldman, and K. Stewart, The Secreted Proteinases from Candida: Challenges for Structure-Aided Drug Design. -- M.N.G. James and E. Bergman, Proteolytic Enzymes of the Viruses of the Family Picornaviridae. -- C. Berry, Proteases as Drug Targets in the Treatment of Malaria. -- J. Cazzulo, Chagas Disease. -- H. Kido, Y. Chen, M. Murakami, Y. Beppu, and T. Towatari, Cellular Proteinases and Viral Infection: Influenza Virus, Sendai Virus, and HIV-1. -- M. Lively, Bacterial Type 1 Signal Peptidases. -- J.A. Garcia, M.R. Fernâandez-Fernâandez, and J.J. Lâopez-Moya, Proteinases Involved in Plant Virus Genome Expression. -- Subject Index.
505 0 0 $t HIV protease as a target for the design of antiviral agents for AIDS / $r John W. Erickson, Michael A. Eissenstat -- $t Proteases of the Hepatitis C virus / $r Andrea Urbani, Raffaele De Francesco, Christian Steinkèuhler -- $t Human herpesvirus proteases / $r Xiayang Qiu, Sherin S. Abdel-Meguid -- $t Secreted proteinases from Candida : challenges for structure-aided drug design / $r Kent Stewart, Robert C. Goldman, Cele Abad-Zapatero -- $t Proteolytic enzymes of the viruses of the family picornaviridae / $r Ernest M. Bergmann, Michael N.G. James -- $t Proteases as drug targets for the treatment of malaria / $r Colin Berry -- $t Chagas disease / $r Juan Josâe Cazzulo -- $t Cellular proteinases and viral infection : Influenza virus, Sendai virus, and HIV-1 / $r Hiroshi Kido ... [et al.] -- $t Bacterial type I signal peptidases / $r Mark O. Lively -- $t Proteinases involved in plant virus genome expression / $r Juan Antonio Garcâia, Marâia Rosario Fernâandez-Fernâandez, Juan Josâe Lâopez-Moya.
520 $a Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery.
588 $a Description based on print version record.
650 0 $a Proteolytic enzymes. $3 796650
650 0 $a Protease inhibitors. $3 862512
650 0 $a Microbial enzymes. $3 680547
650 1 2 $a Protease Inhibitors $x chemical synthesis. $3 862513
650 1 2 $a Protease Inhibitors $x therapeutic use. $3 581416
650 2 2 $a Communicable Diseases $x enzymology. $3 862514
650 2 2 $a Communicable Diseases $x therapy. $3 862515
650 4 $a Communicable diseases. $3 645528
650 6 $a Enzymes proteolytiques. $3 873668
650 6 $a Antiproteases. $3 873669
650 6 $a Enzymes microbiennes. $3 862518
655 4 $a Electronic books. $2 local $3 554714
700 1 $a Dunn, Ben M. $3 862511
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780124205109
938 $a Ingram Digital eBook Collection $b IDEB $n 102511