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The somatotrophic axis in brain function

Record Type:	Language materials, printed : Monograph/item
Title/Author:	The somatotrophic axis in brain function/ edited by Fred J. Nyberg.
other author:	Nyberg, F.
Published:	Burlington, MA :Elsevier Academic Press, : c2006.,
Description:	1 online resource (xii, 340 p.) :ill. (some col.) :
Subject:	Somatotropin. -
Online resource:	http://www.sciencedirect.com/science/book/9780120884841
ISBN:	9780120884841

The somatotrophic axis in brain function
The somatotrophic axis in brain function[electronic resource] /edited by Fred J. Nyberg. - Burlington, MA :Elsevier Academic Press,c2006. - 1 online resource (xii, 340 p.) :ill. (some col.)

Includes bibliographical references and index.

I. Biosynthesis of GH and IGF-I and Regulation of Their Secretion. -- II. GH and IGF-I and their Function at Receptor Level. -- III. Growth Hormone and Insulin-like Growth Factors and Their Receptors in the Central Nervous System. -- IV. CNS Action of Growth Hormone: Basic Studies Using Animal Models. -- V. Immediate and Long-Term Benefits on the CNS and GH Replacement Therapy. -- VI. GH Replacement and Related Therapies in CNS Disorders: A Future Perspective.

The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being reduced in depression. This volume will include chapters (1) on basic knowledge on GH/IGF-1, (2) on localization of GH/IGF-1 and their receptors in the CNS, including blood brain barrier transport of both hormones, (3) on actions of the two hormones on CNS function (basic science), (4) on clinical aspects of GH/IGF-1 in relation to various CNS functions and disorders, and finally (5) on some future perspectives in this area of science. Contents are well balanced and cover a variety of relevant topics from basic to clinical research International selection of authors, with a good representation of the research on growth hormones A timely publication which will be useful to scientists in both basic and clinical research.

ISBN: 9780120884841

Source: 107338:107374Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

673785
Somatotropin.
Index Terms--Genre/Form:

554714
Electronic books.

LC Class. No.: QP572.S6 / S66 2006eb

Dewey Class. No.: 612.8262

National Library of Medicine Call No.: WK 515 / S655 2006

The somatotrophic axis in brain function
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245 0 4 $a The somatotrophic axis in brain function $h [electronic resource] / $c edited by Fred J. Nyberg.
260 $a Burlington, MA : $b Elsevier Academic Press, $c c2006.
300 $a 1 online resource (xii, 340 p.) : $b ill. (some col.)
504 $a Includes bibliographical references and index.
505 0 $a I. Biosynthesis of GH and IGF-I and Regulation of Their Secretion. -- II. GH and IGF-I and their Function at Receptor Level. -- III. Growth Hormone and Insulin-like Growth Factors and Their Receptors in the Central Nervous System. -- IV. CNS Action of Growth Hormone: Basic Studies Using Animal Models. -- V. Immediate and Long-Term Benefits on the CNS and GH Replacement Therapy. -- VI. GH Replacement and Related Therapies in CNS Disorders: A Future Perspective.
520 $a The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being reduced in depression. This volume will include chapters (1) on basic knowledge on GH/IGF-1, (2) on localization of GH/IGF-1 and their receptors in the CNS, including blood brain barrier transport of both hormones, (3) on actions of the two hormones on CNS function (basic science), (4) on clinical aspects of GH/IGF-1 in relation to various CNS functions and disorders, and finally (5) on some future perspectives in this area of science. Contents are well balanced and cover a variety of relevant topics from basic to clinical research International selection of authors, with a good representation of the research on growth hormones A timely publication which will be useful to scientists in both basic and clinical research.
588 $a Description based on print version record.
650 0 $a Somatotropin. $3 673785
650 0 $a Growth hormone releasing factor. $3 863283
650 0 $a Neuroendocrinology. $3 581534
650 1 2 $a Somatotropin-Releasing Hormone $x physiology. $3 863284
650 2 2 $a Growth Hormone $x physiology. $3 863285
650 2 2 $a Neuroendorinology. $3 863286
650 2 2 $a Receptors, Somatotropin $x physiology. $3 863287
650 2 2 $a Somatomedins $x physiology. $3 863288
650 6 $a Somatotrophine. $3 863289
650 6 $a Somatocrinine. $3 863290
650 6 $a Neuroendocrinologie. $3 863291
650 7 $a MEDICAL $x Neuroscience. $2 bisacsh $3 788872
650 7 $a PSYCHOLOGY $x Neuropsychology. $2 bisacsh $3 788873
655 4 $a Electronic books. $2 local $3 554714
700 1 $a Nyberg, F. $3 863282
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780120884841
938 $a ebrary $b EBRY $n ebr10180523