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High-throughput screening methods in...
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Steinberg, Pablo.
High-throughput screening methods in toxicity testing
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
High-throughput screening methods in toxicity testing/ edited by Pablo Steinberg.
其他作者:
Steinberg, Pablo.
出版者:
Hoboken, New Jersey :John Wiley & Sons Inc., : 2013.,
面頁冊數:
1 online resource.
附註:
Includes index.
標題:
High throughput screening (Drug development) -
電子資源:
http://onlinelibrary.wiley.com/book/10.1002/9781118538203
ISBN:
9781118538180 (electronic bk.)
High-throughput screening methods in toxicity testing
High-throughput screening methods in toxicity testing
[electronic resource] /edited by Pablo Steinberg. - Hoboken, New Jersey :John Wiley & Sons Inc.,2013. - 1 online resource.
Includes index.
Includes bibliographical references and index.
pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.
"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"--
ISBN: 9781118538180 (electronic bk.)Subjects--Topical Terms:
582128
High throughput screening (Drug development)
Index Terms--Genre/Form:
554714
Electronic books.
LC Class. No.: RS419.5 / .H542 2013eb
Dewey Class. No.: 615.1/9
High-throughput screening methods in toxicity testing
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pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.
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"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"--
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"This book describes the high-throughput in vitro methods available for toxicity testing, serving as a guide to scientists working in toxicity evaluation and risk assessment of chemicals and drugs"--
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http://onlinelibrary.wiley.com/book/10.1002/9781118538203
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