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Lean biomanufacturing = creating value through innovative bioprocessing approaches /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Lean biomanufacturing/ NigelJ. Smart.
Reminder of title:	creating value through innovative bioprocessing approaches /
Author:	Smart, Nigel J.
Published:	Oxford ;Woodhead Publishing, : 2013.,
Description:	xxvii, 355 p. :ill. ; : 25 cm.;
Subject:	Drugs - Prices - United States. -
Online resource:	click for full text (2015 TAEBDC PDA eBooks Trial, Trial Period: 2015.6.3-2015.12.31)
ISBN:	9781907568787 (electronic bk.)

Lean biomanufacturing = creating value through innovative bioprocessing approaches /
Smart, Nigel J.

Lean biomanufacturingcreating value through innovative bioprocessing approaches /[electronic resource] :NigelJ. Smart. - 1st ed. - Oxford ;Woodhead Publishing,2013. - xxvii, 355 p. :ill. ;25 cm. - Woodhead Publishing series in biomedicine ;no. 37. - Woodhead Publishing series in biomedicine ;no. 9..

Includes bibliographical references and index.

1. An introduction to Lean biomanufacturing -- 2. Lean technologies/methods to be applied to biomanufacturing -- 3. Creation, execution and implementation of the Transition Plan -- 4. Issues and problems for the biopharmaceutical industry that make the situation challenging -- 5. Developing a Lean approach to biopharmaceutical processes -- 6. The contribution of simulation models in the development of Lean biopharmaceutical processes -- 7. Integration of biomanufacturing with Lean laboratory operations -- 8. Lean compliance and considerations connected with enablingLean manufacturing -- 9. Ready to use technologies and their role in Lean biomanufacturing.

With decreasing profit margins, increasing cost pressures,growing regulatory compliance concerns, mounting pressure from generic drugs and increasing anxiety about the futureof healthcare reimbursement, pharmaceutical manufacturers are now forced to re-examine and re-assess the way they have been doing things. In order to sustain profitability,these companies are looking to reduce waste (of all kinds),improve efficiency and increase productivity. Many of themare taking a closer look at lean manufacturing as a way toachieve these goals. Lean biomanufacturing re-visits lean principles and then applies them sympathetically - in a highly practical approach - to the specific needs of pharmaceutical processes, which present significantly different challenges to more mainstream manufacturing processes. A major goal of the book is to highlight those problems and issues that appear more specific or unique tobiopharmaceutical manufacturing situations and to provide some insights into what challenges are the important ones to solve and what techniques, tools and mechanisms to employ to be successful. Following an introduction to leanbiomanufacturing, the book goes on to discuss lean technologies and methods applied in biomanufacturing. Later chapters cover the creation and implementation of the Transition Plan, issues facing the biopharmaceutical industry, creating a lean approach towards biopharmaceutical processes and the contribution of simulation models in developing these processes. The finalchapter covers examples of new technology innovations which help facilitate lean biomanufacturing. A focus on the issues associated with the application of lean principles to biomanufacturingPractical examples of factors which can affect biopharmaceutical processesCoverage of key factors which require integrationto run an efficient biopharmaceutical process.

ISBN: 9781907568787 (electronic bk.)Subjects--Topical Terms:

1029752
Drugs
--Prices--United States.

LC Class. No.: HD9665.5 / .S578 2013

Dewey Class. No.: 615.1/900685

National Library of Medicine Call No.: QV 55

Lean biomanufacturing = creating value through innovative bioprocessing approaches /
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