語系:
繁體中文
English
說明(常見問題)
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
Peptidomimetics in organic and medic...
~
Guarna, Antonio.
Peptidomimetics in organic and medicinal chemistry DUP_1 = the art of transforming peptides in drugs /
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Peptidomimetics in organic and medicinal chemistry DUP_1/ Andrea Trabocchi and Antonio Guarna.
其他題名:
the art of transforming peptides in drugs /
作者:
Trabocchi, Andrea.
其他作者:
Guarna, Antonio.
出版者:
Chichester, West Sussex ;Wiley, : 2014.,
面頁冊數:
1 online resource. (xix, 288 p.) :ill. :
標題:
Peptide drugs. -
電子資源:
http://onlinelibrary.wiley.com/book/10.1002/9781118683033
ISBN:
9781118683033 (electronic bk.)
Peptidomimetics in organic and medicinal chemistry DUP_1 = the art of transforming peptides in drugs /
Trabocchi, Andrea.
Peptidomimetics in organic and medicinal chemistry DUP_1
the art of transforming peptides in drugs /[electronic resource] :Andrea Trabocchi and Antonio Guarna. - Chichester, West Sussex ;Wiley,2014. - 1 online resource. (xix, 288 p.) :ill.
Includes bibliographical references and index.
"A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands. Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery"--
ISBN: 9781118683033 (electronic bk.)
LCCN: 2013051081Subjects--Topical Terms:
778499
Peptide drugs.
LC Class. No.: RS431.P38
Dewey Class. No.: 615.1/9
Peptidomimetics in organic and medicinal chemistry DUP_1 = the art of transforming peptides in drugs /
LDR
:02509cam a22003498i 4500
001
832574
003
OCoLC
005
20140507095750.0
006
m o d
007
cr |||||||||||
008
160127s2014 enka ob 001 0 eng
010
$a
2013051081
020
$a
9781118683033 (electronic bk.)
020
$a
111868303X (electronic bk.)
020
$a
9781118683842 (electronic bk.)
020
$a
1118683846 (electronic bk.)
020
$z
9781118683149
020
$z
1118683145
020
$z
9781119950608 (hardback)
020
$z
1119950600 (hardback)
035
$a
(OCoLC)867001313
035
$a
ocn867001313
040
$a
DLC
$b
eng
$c
DLC
$d
OCLCO
$d
N
$d
YDXCP
$d
DG1
$d
IDEBK
$d
CUS
050
1 0
$a
RS431.P38
082
0 0
$a
615.1/9
$2
23
100
1
$a
Trabocchi, Andrea.
$3
1000441
245
1 0
$a
Peptidomimetics in organic and medicinal chemistry DUP_1
$h
[electronic resource] :
$b
the art of transforming peptides in drugs /
$c
Andrea Trabocchi and Antonio Guarna.
260
$a
Chichester, West Sussex ;
$a
Hoboken, N.J. :
$b
Wiley,
$c
2014.
300
$a
1 online resource. (xix, 288 p.) :
$b
ill.
504
$a
Includes bibliographical references and index.
520
$a
"A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity. It is a very powerful approach for the generation of small-molecule-based drugs as enzyme inhibitors or receptor ligands. Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature. Topics covered include the chemistry of unnatural amino acids, peptide- and scaffold-based peptidomimetics, amino acid-side chain isosteres, backbone isosteres, dipeptide isosteres, beta-turn peptidomimetics, proline-mimetics as turn inducers, cyclic scaffolds, amino acid surrogates, and scaffolds for combinatorial chemistry of peptidomimetics. Case studies in the hit-to-lead process, such as the development of integrin ligands and thrombin inhibitors, illustrate the successful application of peptidomimetics in drug discovery"--
$c
Provided by publisher.
520
$a
"Peptidomimetics in Organic and Medicinal Chemistry outlines the concepts and synthetic strategies underlying the building of bioactive compounds of a peptidomimetic nature"--
$c
Provided by publisher.
588
$a
Description based on online resource; title from PDF title page (Wiley, viewed April 3, 2014)
650
0
$a
Peptide drugs.
$3
778499
650
0
$a
Proteins
$x
Therapeutic use.
$3
778498
650
0
$a
Drugs
$x
Design.
$3
582269
700
1
$a
Guarna, Antonio.
$3
1059378
856
4 0
$u
http://onlinelibrary.wiley.com/book/10.1002/9781118683033
筆 0 讀者評論
多媒體
評論
新增評論
分享你的心得
Export
取書館別
處理中
...
變更密碼[密碼必須為2種組合(英文和數字)及長度為10碼以上]
登入