Language:
English
繁體中文
Help
Login
Back
Switch To:
Labeled
|
MARC Mode
|
ISBD
Lipid nanoparticles = production, ch...
~
Shah, Rohan.
Lipid nanoparticles = production, characterization and stability /
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Lipid nanoparticles/ by Rohan Shah ... [et al.].
Reminder of title:
production, characterization and stability /
other author:
Shah, Rohan.
Published:
Cham :Springer International Publishing : : 2015.,
Description:
ix, 97 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:
Springer eBooks
Subject:
Nanoparticles. -
Online resource:
http://dx.doi.org/10.1007/978-3-319-10711-0
ISBN:
9783319107110 (electronic bk.)
Lipid nanoparticles = production, characterization and stability /
Lipid nanoparticles
production, characterization and stability /[electronic resource] :by Rohan Shah ... [et al.]. - Cham :Springer International Publishing :2015. - ix, 97 p. :ill. (some col.), digital ;24 cm. - SpringerBriefs in pharmaceutical science & drug development,1864-8118. - SpringerBriefs in pharmaceutical science & drug development..
Introduction -- Composition and structure -- Production techniques -- Characterization -- Physicochemical stability.
What are lipid nanoparticles? How are they structured? How are they formed? What techniques are best to characterize them How great is their potential as drug delivery systems? These questions and more are answered in this comprehensive and highly readable work on lipid nanoparticles. This work sets out to provide the reader with a clear and understandable understanding of the current practices in formulation, characterization and drug delivery of lipid nanoparticles. A comprehensive description of the current understanding of synthesis, characterization, stability optimization and drug incorporation of solid lipid nanoparticles is provided. Nanoparticles have attracted great interest over the past few decades with almost exponential growth in their research and application. Their small particle size and subsequent high surface area make them ideal in many uses, but particularly as drug carrier systems. Nanoparticles made from lipids are especially attractive because of their enhanced biocompatibility imparted by the lipid. The work provides a detailed description of the types of lipid nanoparticles available (e.g. SLN, NLC, LDC, PLN) and how they range from imperfect crystalline to amorphous in structure. Current thoughts on where drugs are situated (e.g. in the core, or at the interface) and how this can be manipulated are discussed. The many techniques for production, including the author's own variant of microwave heating, are fully discussed. Techniques for measuring arguably the most important characteristics of particle size and polydispersity are discussed, along with techniques to measure crystallinity, shape and drug capacity. Finally, a full chapter on techniques for measuring stability, both in the absence and presence of drugs, is discussed, along with suggestions on how to optimize that stability. This work appeals to students of colloid science, practitioners of research into drug delivery and academics alike.
ISBN: 9783319107110 (electronic bk.)
Standard No.: 10.1007/978-3-319-10711-0doiSubjects--Topical Terms:
596762
Nanoparticles.
LC Class. No.: RS201.N35
Dewey Class. No.: 620.5
Lipid nanoparticles = production, characterization and stability /
LDR
:03112nam a2200325 a 4500
001
834243
003
DE-He213
005
20150519111340.0
006
m d
007
cr nn 008maaau
008
160421s2015 gw s 0 eng d
020
$a
9783319107110 (electronic bk.)
020
$a
9783319107103 (paper)
024
7
$a
10.1007/978-3-319-10711-0
$2
doi
035
$a
978-3-319-10711-0
040
$a
GP
$c
GP
041
0
$a
eng
050
4
$a
RS201.N35
072
7
$a
TDCW
$2
bicssc
072
7
$a
MED072000
$2
bisacsh
082
0 4
$a
620.5
$2
23
090
$a
RS201.N35
$b
L764 2015
245
0 0
$a
Lipid nanoparticles
$h
[electronic resource] :
$b
production, characterization and stability /
$c
by Rohan Shah ... [et al.].
260
$a
Cham :
$c
2015.
$b
Springer International Publishing :
$b
Imprint: Springer,
300
$a
ix, 97 p. :
$b
ill. (some col.), digital ;
$c
24 cm.
490
1
$a
SpringerBriefs in pharmaceutical science & drug development,
$x
1864-8118
505
0
$a
Introduction -- Composition and structure -- Production techniques -- Characterization -- Physicochemical stability.
520
$a
What are lipid nanoparticles? How are they structured? How are they formed? What techniques are best to characterize them How great is their potential as drug delivery systems? These questions and more are answered in this comprehensive and highly readable work on lipid nanoparticles. This work sets out to provide the reader with a clear and understandable understanding of the current practices in formulation, characterization and drug delivery of lipid nanoparticles. A comprehensive description of the current understanding of synthesis, characterization, stability optimization and drug incorporation of solid lipid nanoparticles is provided. Nanoparticles have attracted great interest over the past few decades with almost exponential growth in their research and application. Their small particle size and subsequent high surface area make them ideal in many uses, but particularly as drug carrier systems. Nanoparticles made from lipids are especially attractive because of their enhanced biocompatibility imparted by the lipid. The work provides a detailed description of the types of lipid nanoparticles available (e.g. SLN, NLC, LDC, PLN) and how they range from imperfect crystalline to amorphous in structure. Current thoughts on where drugs are situated (e.g. in the core, or at the interface) and how this can be manipulated are discussed. The many techniques for production, including the author's own variant of microwave heating, are fully discussed. Techniques for measuring arguably the most important characteristics of particle size and polydispersity are discussed, along with techniques to measure crystallinity, shape and drug capacity. Finally, a full chapter on techniques for measuring stability, both in the absence and presence of drugs, is discussed, along with suggestions on how to optimize that stability. This work appeals to students of colloid science, practitioners of research into drug delivery and academics alike.
650
0
$a
Nanoparticles.
$3
596762
650
0
$a
Lipids.
$3
556565
650
0
$a
Lipids
$x
Biotechnology.
$3
557351
650
1 4
$a
Biomedicine.
$3
593880
650
2 4
$a
Pharmaceutical Sciences/Technology.
$3
768561
650
2 4
$a
Biotechnology.
$3
554955
650
2 4
$a
Lipidology.
$3
681911
700
1
$a
Shah, Rohan.
$3
1062550
710
2
$a
SpringerLink (Online service)
$3
593884
773
0
$t
Springer eBooks
830
0
$a
SpringerBriefs in pharmaceutical science & drug development.
$3
885020
856
4 0
$u
http://dx.doi.org/10.1007/978-3-319-10711-0
950
$a
Medicine (Springer-11650)
based on 0 review(s)
Multimedia
Reviews
Add a review
and share your thoughts with other readers
Export
pickup library
Processing
...
Change password
Login