國立虎尾科技大學 |

Urine proteomics in kidney disease biomarker discovery

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Urine proteomics in kidney disease biomarker discovery/ edited by Youhe Gao.
其他作者:	Gao, Youhe.
出版者:	Dordrecht :Springer Netherlands : : 2015.,
面頁冊數:	xiii, 203 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Urine - Analysis. -
電子資源:	http://dx.doi.org/10.1007/978-94-017-9523-4
ISBN:	9789401795234 (electronic bk.)

Urine proteomics in kidney disease biomarker discovery
Urine proteomics in kidney disease biomarker discovery[electronic resource] /edited by Youhe Gao. - Dordrecht :Springer Netherlands :2015. - xiii, 203 p. :ill. (some col.), digital ;24 cm. - Advances in experimental medicine and biology,v.8450065-2598 ;. - Advances in experimental medicine and biology ;780..

Urine is a better biomarker source than blood especially for kidney diseases -- Urine reflection of changes in blood -- Urimem facilitates kidney disease biomarker research -- Human Urine proteome: a powerful source for clinical research -- Exosomes in urine biomarker discovery -- Urinary proteins with post-translational modifications -- Applications of peptide retention time in proteomic data analysis -- Urine Sample Preparation in 96-Well Filter Plates to characterize inflammatory and infectious diseases of the Urinary Tract -- Variations of human urinary proteome -- Evolution of the urinary proteome during human renal development and maturation -- Hormone-dependent changes in female urinary proteome -- Effects of exercise on the urinary proteome -- Effects of Diuretics on Urinary Proteins -- Applications of urinary proteomics in renal disease research using animal models -- The application of urinary proteomics for the detection of biomarkers of kidney diseases -- Dynamic changes of urinary proteins in focal segmental glomerulosclerosis model -- Using isolated rat kidney to discover kidney origin biomarkers in urine -- Comparing plasma and urinary proteomes to understand kidney function -- Urinary Protein Biomarker Database: A Useful Tool for Biomarker Discovery.

This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the potential opportunities and risks in their study design. Kidney diseases are emphasized as they produce the most significant changes in urine. This book tries to show researchers and graduate students, who are in or entering the field, "all things considered" rather than "the current affair".

ISBN: 9789401795234 (electronic bk.)

Standard No.: 10.1007/978-94-017-9523-4doiSubjects--Topical Terms:

1063090
Urine
--Analysis.

LC Class. No.: RB53

Dewey Class. No.: 612.461

Urine proteomics in kidney disease biomarker discovery
LDR:03010nam a2200325 a 4500 001 834542
003 DE-He213
005 20150610103927.0
006 m d
007 cr nn 008maaau
008 160421s2015 ne s 0 eng d
020 $a 9789401795234 (electronic bk.)
020 $a 9789401795227 (paper)
024 7 $a 10.1007/978-94-017-9523-4 $2 doi
035 $a 978-94-017-9523-4
040 $a GP $c GP
041 0 $a eng
050 4 $a RB53
072 7 $a PSBC $2 bicssc
072 7 $a SCI007000 $2 bisacsh
082 0 4 $a 612.461 $2 23
090 $a RB53 $b .U76 2015
245 0 0 $a Urine proteomics in kidney disease biomarker discovery $h [electronic resource] / $c edited by Youhe Gao.
260 $a Dordrecht : $c 2015. $b Springer Netherlands : $b Imprint: Springer,
300 $a xiii, 203 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.845
505 0 $a Urine is a better biomarker source than blood especially for kidney diseases -- Urine reflection of changes in blood -- Urimem facilitates kidney disease biomarker research -- Human Urine proteome: a powerful source for clinical research -- Exosomes in urine biomarker discovery -- Urinary proteins with post-translational modifications -- Applications of peptide retention time in proteomic data analysis -- Urine Sample Preparation in 96-Well Filter Plates to characterize inflammatory and infectious diseases of the Urinary Tract -- Variations of human urinary proteome -- Evolution of the urinary proteome during human renal development and maturation -- Hormone-dependent changes in female urinary proteome -- Effects of exercise on the urinary proteome -- Effects of Diuretics on Urinary Proteins -- Applications of urinary proteomics in renal disease research using animal models -- The application of urinary proteomics for the detection of biomarkers of kidney diseases -- Dynamic changes of urinary proteins in focal segmental glomerulosclerosis model -- Using isolated rat kidney to discover kidney origin biomarkers in urine -- Comparing plasma and urinary proteomes to understand kidney function -- Urinary Protein Biomarker Database: A Useful Tool for Biomarker Discovery.
520 $a This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the potential opportunities and risks in their study design. Kidney diseases are emphasized as they produce the most significant changes in urine. This book tries to show researchers and graduate students, who are in or entering the field, "all things considered" rather than "the current affair".
650 0 $a Urine $x Analysis. $3 1063090
650 0 $a Biochemical markers. $3 582469
650 0 $a Kidneys $x Diseases $x Diagnosis. $3 1063091
650 1 4 $a Life Sciences. $3 593888
650 2 4 $a Proteomics. $3 581930
650 2 4 $a Nephrology. $3 668354
650 2 4 $a Molecular Medicine. $3 668353
700 1 $a Gao, Youhe. $3 1063089
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v 780. $3 881230
856 4 0 $u http://dx.doi.org/10.1007/978-94-017-9523-4
950 $a Biomedical and Life Sciences (Springer-11642)