國立虎尾科技大學 |

Resistance to photodynamic therapy in cancer

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Resistance to photodynamic therapy in cancer/ edited by Valentina Rapozzi, Giulio Jori.
其他作者:	Rapozzi, Valentina.
出版者:	Cham :Springer International Publishing : : 2015.,
面頁冊數:	xiii, 248 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Cancer - Photochemotherapy. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-12730-9
ISBN:	9783319127309 (electronic bk.)

Resistance to photodynamic therapy in cancer
Resistance to photodynamic therapy in cancer[electronic resource] /edited by Valentina Rapozzi, Giulio Jori. - Cham :Springer International Publishing :2015. - xiii, 248 p. :ill. (some col.), digital ;24 cm. - Resistance to targeted anti-cancer therapeutics,v.52196-5501 ;. - Resistance to targeted anti-cancer therapeutics ;v.4..

Basic and Clinical Aspects of photodynamic Therapy -- Mechanisms of Resistance to Photodynamic Therapy -- Tumor Vascular Microenvironment Determines responsiveness to Photodynamic Therapy -- Autophagy Pathways Activated in Response to PDT Contribute to Cell Resistance Against ROS Damage -- Methods to isolate the Resistant Cells to Photodynamic Therapy -- GRP78-Targeting Subtilase Cytotoxin Sensitizes Cancer Cells to Photodynamic Therapy -- Optimization of Photodynamic Therapy Response by Survivin Gene Knockdown in Human Metastatic Breast Cancer -- Cellular Targets and Molecular Responses Associated with Photodynamic Therapy -- The Use of Nanoparticle-Delivered Photosensitizers Can Overcome the Development of Resistance to PDT in Tumors -- Mechanisms of tumor cells resistance to ALA/PDT -- Overcoming the Resistance of Meolanoma to Photodynamic Therapy.

This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic therapy is a minimally invasive therapeutic procedure that can exert a selective or preferential cytotoxic activity toward malignant cells. The procedure involves administration of an intrinsically non-toxic photosensitizing agent (PS) followed by irradiation at a wavelength corresponding to a visible absorption band of the sensitizer. In the presence of oxygen, a series of events lead to direct tumor cell death, damage to the microvasculature, and induction of a local inflammatory reaction. Studies reveal that PDT can be curative, particularly in early stage tumors and this volume explores the potential of PDT, but also reveals strategic approaches to overcome resistance in tumor cells.

ISBN: 9783319127309 (electronic bk.)

Standard No.: 10.1007/978-3-319-12730-9doiSubjects--Topical Terms:

1023547
Cancer
--Photochemotherapy.

LC Class. No.: RC271.P43

Dewey Class. No.: 616.9940631

Resistance to photodynamic therapy in cancer
LDR:02910nam a2200325 a 4500 001 835521
003 DE-He213
005 20150729160942.0
006 m d
007 cr nn 008maaau
008 160421s2015 gw s 0 eng d
020 $a 9783319127309 (electronic bk.)
020 $a 9783319127293 (paper)
024 7 $a 10.1007/978-3-319-12730-9 $2 doi
035 $a 978-3-319-12730-9
040 $a GP $c GP
041 0 $a eng
050 4 $a RC271.P43
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
082 0 4 $a 616.9940631 $2 23
090 $a RC271.P43 $b R433 2015
245 0 0 $a Resistance to photodynamic therapy in cancer $h [electronic resource] / $c edited by Valentina Rapozzi, Giulio Jori.
260 $a Cham : $c 2015. $b Springer International Publishing : $b Imprint: Springer,
300 $a xiii, 248 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Resistance to targeted anti-cancer therapeutics, $x 2196-5501 ; $v v.5
505 0 $a Basic and Clinical Aspects of photodynamic Therapy -- Mechanisms of Resistance to Photodynamic Therapy -- Tumor Vascular Microenvironment Determines responsiveness to Photodynamic Therapy -- Autophagy Pathways Activated in Response to PDT Contribute to Cell Resistance Against ROS Damage -- Methods to isolate the Resistant Cells to Photodynamic Therapy -- GRP78-Targeting Subtilase Cytotoxin Sensitizes Cancer Cells to Photodynamic Therapy -- Optimization of Photodynamic Therapy Response by Survivin Gene Knockdown in Human Metastatic Breast Cancer -- Cellular Targets and Molecular Responses Associated with Photodynamic Therapy -- The Use of Nanoparticle-Delivered Photosensitizers Can Overcome the Development of Resistance to PDT in Tumors -- Mechanisms of tumor cells resistance to ALA/PDT -- Overcoming the Resistance of Meolanoma to Photodynamic Therapy.
520 $a This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic therapy is a minimally invasive therapeutic procedure that can exert a selective or preferential cytotoxic activity toward malignant cells. The procedure involves administration of an intrinsically non-toxic photosensitizing agent (PS) followed by irradiation at a wavelength corresponding to a visible absorption band of the sensitizer. In the presence of oxygen, a series of events lead to direct tumor cell death, damage to the microvasculature, and induction of a local inflammatory reaction. Studies reveal that PDT can be curative, particularly in early stage tumors and this volume explores the potential of PDT, but also reveals strategic approaches to overcome resistance in tumor cells.
650 0 $a Cancer $x Photochemotherapy. $3 1023547
650 0 $a Drug resistance in cancer cells. $3 681914
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Cancer Research. $3 668358
650 2 4 $a Drug Resistance. $3 782695
650 2 4 $a Molecular Medicine. $3 668353
700 1 $a Rapozzi, Valentina. $3 1064888
700 1 $a Jori, Giulio. $3 1064889
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Resistance to targeted anti-cancer therapeutics ; $v v.4. $3 1063064
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-12730-9
950 $a Biomedical and Life Sciences (Springer-11642)