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Pre-analytics of pathological specimens in oncology

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Pre-analytics of pathological specimens in oncology/ edited by Manfred Dietel ... [et al.].
other author:	Dietel, Manfred.
Published:	Cham :Springer International Publishing : : 2015.,
Description:	vi, 133 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Cancer - Diagnosis. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-13957-9
ISBN:	9783319139579 (electronic bk.)

Pre-analytics of pathological specimens in oncology
Pre-analytics of pathological specimens in oncology[electronic resource] /edited by Manfred Dietel ... [et al.]. - Cham :Springer International Publishing :2015. - vi, 133 p. :ill., digital ;24 cm. - Recent results in cancer research,v.1990080-0015 ;. - Recent results in cancer research ;v.196..

What Is Pre-Analytics in Surgical Pathology? -- Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics – Where to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge.

This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pathological processing - have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.

ISBN: 9783319139579 (electronic bk.)

Standard No.: 10.1007/978-3-319-13957-9doiSubjects--Topical Terms:

661324
Cancer
--Diagnosis.

LC Class. No.: RC270

Dewey Class. No.: 616.994075

Pre-analytics of pathological specimens in oncology
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520 $a This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pathological processing - have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.
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