國立虎尾科技大學 |

The essential guide to N-of-1 trials in health

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	The essential guide to N-of-1 trials in health/ edited by Jane Nikles, Geoffrey Mitchell.
其他作者:	Mitchell, Geoffrey.
出版者:	Dordrecht :Imprint: Springer, : 2015.,
面頁冊數:	xi, 245 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Pharmacy. -
電子資源:	http://dx.doi.org/10.1007/978-94-017-7200-6
ISBN:	9789401772006

The essential guide to N-of-1 trials in health
The essential guide to N-of-1 trials in health[electronic resource] /edited by Jane Nikles, Geoffrey Mitchell. - Dordrecht :Imprint: Springer,2015. - xi, 245 p. :ill., digital ;24 cm.

Preface -- Introduction -- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences -- N-of-1 trials in medical contexts -- Aggregated N-of-1 trials -- Methodological considerations for N-of-1 trials -- Randomization, allocation concealment and blinding -- Data collection and quality control -- Individual reporting of N-of-1 trials to patients and clinicians -- Assessing and reporting adverse events -- Research ethics and N-of-1 trials -- Statistical analysis of N-of-1 trials -- The economics of N-of-1 trials -- Reporting N-of-1 trials to professional audiences -- Single patient open trials -- Systematic review and meta-analysis using N-of-1 trials -- Where are N-of-1 trials headed? -- Index.

N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the world's leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.

ISBN: 9789401772006

Standard No.: 10.1007/978-94-017-7200-6doiSubjects--Topical Terms:

582411
Pharmacy.

LC Class. No.: RM301.27 / .E77 2015

Dewey Class. No.: 615.1901

The essential guide to N-of-1 trials in health
LDR:02625nam a2200313 a 4500 001 838078
003 DE-He213
005 20160415091128.0
006 m d
007 cr nn 008maaau
008 160616s2015 ne s 0 eng d
020 $a 9789401772006 $q (electronic bk.)
020 $a 9789401771993 $q (paper)
024 7 $a 10.1007/978-94-017-7200-6 $2 doi
035 $a 978-94-017-7200-6
040 $a GP $c GP
041 0 $a eng
050 4 $a RM301.27 $b .E77 2015
072 7 $a MBGR $2 bicssc
072 7 $a MED000000 $2 bisacsh
082 0 4 $a 615.1901 $2 23
090 $a RM301.27 $b .E78 2015
245 0 4 $a The essential guide to N-of-1 trials in health $h [electronic resource] / $c edited by Jane Nikles, Geoffrey Mitchell.
260 $a Dordrecht : $c 2015. $b Imprint: Springer, $b Springer Netherlands :
300 $a xi, 245 p. : $b ill., digital ; $c 24 cm.
505 0 $a Preface -- Introduction -- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences -- N-of-1 trials in medical contexts -- Aggregated N-of-1 trials -- Methodological considerations for N-of-1 trials -- Randomization, allocation concealment and blinding -- Data collection and quality control -- Individual reporting of N-of-1 trials to patients and clinicians -- Assessing and reporting adverse events -- Research ethics and N-of-1 trials -- Statistical analysis of N-of-1 trials -- The economics of N-of-1 trials -- Reporting N-of-1 trials to professional audiences -- Single patient open trials -- Systematic review and meta-analysis using N-of-1 trials -- Where are N-of-1 trials headed? -- Index.
520 $a N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the world's leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.
650 2 4 $a Pharmacy. $3 582411
650 2 4 $a Statistics for Life Sciences, Medicine, Health Sciences. $3 670172
650 2 4 $a Psychology, general. $3 668226
650 2 4 $a Pharmacotherapy. $3 973587
650 2 4 $a Biomedicine general. $3 668531
650 1 4 $a Biomedicine. $3 593880
650 0 $a Crossover trials. $3 1069005
650 0 $a Drugs $x Testing. $3 581825
700 1 $a Mitchell, Geoffrey. $3 1069004
700 1 $a Nikles, Jane. $3 1069003
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-94-017-7200-6
950 $a Biomedical and Life Sciences (Springer-11642)