國立虎尾科技大學 |

Stochastic narrow escape in molecular and cellular biology = analysis and applications /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Stochastic narrow escape in molecular and cellular biology/ by David Holcman, Zeev Schuss.
其他題名:	analysis and applications /
作者:	Holcman, David.
其他作者:	Schuss, Zeev.
出版者:	New York, NY :Springer New York : : 2015.,
面頁冊數:	xix, 259 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Numerical and Computational Physics. -
電子資源:	http://dx.doi.org/10.1007/978-1-4939-3103-3
ISBN:	9781493931033

Stochastic narrow escape in molecular and cellular biology = analysis and applications /
Holcman, David.

Stochastic narrow escape in molecular and cellular biologyanalysis and applications /[electronic resource] :by David Holcman, Zeev Schuss. - New York, NY :Springer New York :2015. - xix, 259 p. :ill., digital ;24 cm.

Elementary Theory of Stochastic Narrow Escape -- Special Asymptotics for Stochastic Narrow Escape -- NET in Molecular and Cellular Biology -- Applications to Cellular Biology and Simulations -- Determination of Features from Super-Resolution Data -- Markov Models for Stochastic Chemical Reactions -- Random Search with Switching -- Narrow Escape in Other Cellular Processes -- Modeling the Early Steps of Viral Infection in Cells.

This book covers recent developments in the non-standard asymptotics of the mathematical narrow escape problem in stochastic theory, as well as applications of the narrow escape problem in cell biology. The first part of the book concentrates on mathematical methods, including advanced asymptotic methods in partial equations, and is aimed primarily at applied mathematicians and theoretical physicists who are interested in biological applications. The second part of the book is intended for computational biologists, theoretical chemists, biochemists, biophysicists, and physiologists. It includes a summary of output formulas from the mathematical portion of the book and concentrates on their applications in modeling specific problems in theoretical molecular and cellular biology. Critical biological processes, such as synaptic plasticity and transmission, activation of genes by transcription factors, or double-strained DNA break repair, are controlled by diffusion in structures that have both large and small spatial scales. These may be small binding sites inside or on the surface of the cell, or narrow passages between subcellular compartments. The great disparity in spatial scales is the key to controlling cell function by structure. This volume reports recent progress on resolving analytical and numerical difficulties in extracting properties from experimental data, biophysical models, and from Brownian dynamics simulations of diffusion in multi-scale structures.

ISBN: 9781493931033

Standard No.: 10.1007/978-1-4939-3103-3doiSubjects--Topical Terms:

768904
Numerical and Computational Physics.

LC Class. No.: QA274

Dewey Class. No.: 519.2

Stochastic narrow escape in molecular and cellular biology = analysis and applications /
LDR:02927nam a2200325 a 4500 001 838759
003 DE-He213
005 20160407104325.0
006 m d
007 cr nn 008maaau
008 160616s2015 nyu s 0 eng d
020 $a 9781493931033 $q (electronic bk.)
020 $a 9781493931026 $q (paper)
024 7 $a 10.1007/978-1-4939-3103-3 $2 doi
035 $a 978-1-4939-3103-3
040 $a GP $c GP
041 0 $a eng
050 4 $a QA274
072 7 $a PHVN $2 bicssc
072 7 $a PHVD $2 bicssc
072 7 $a SCI009000 $2 bisacsh
082 0 4 $a 519.2 $2 23
090 $a QA274 $b .H725 2015
100 1 $a Holcman, David. $3 1070127
245 1 0 $a Stochastic narrow escape in molecular and cellular biology $h [electronic resource] : $b analysis and applications / $c by David Holcman, Zeev Schuss.
260 $a New York, NY : $b Springer New York : $b Imprint: Springer, $c 2015.
300 $a xix, 259 p. : $b ill., digital ; $c 24 cm.
505 0 $a Elementary Theory of Stochastic Narrow Escape -- Special Asymptotics for Stochastic Narrow Escape -- NET in Molecular and Cellular Biology -- Applications to Cellular Biology and Simulations -- Determination of Features from Super-Resolution Data -- Markov Models for Stochastic Chemical Reactions -- Random Search with Switching -- Narrow Escape in Other Cellular Processes -- Modeling the Early Steps of Viral Infection in Cells.
520 $a This book covers recent developments in the non-standard asymptotics of the mathematical narrow escape problem in stochastic theory, as well as applications of the narrow escape problem in cell biology. The first part of the book concentrates on mathematical methods, including advanced asymptotic methods in partial equations, and is aimed primarily at applied mathematicians and theoretical physicists who are interested in biological applications. The second part of the book is intended for computational biologists, theoretical chemists, biochemists, biophysicists, and physiologists. It includes a summary of output formulas from the mathematical portion of the book and concentrates on their applications in modeling specific problems in theoretical molecular and cellular biology. Critical biological processes, such as synaptic plasticity and transmission, activation of genes by transcription factors, or double-strained DNA break repair, are controlled by diffusion in structures that have both large and small spatial scales. These may be small binding sites inside or on the surface of the cell, or narrow passages between subcellular compartments. The great disparity in spatial scales is the key to controlling cell function by structure. This volume reports recent progress on resolving analytical and numerical difficulties in extracting properties from experimental data, biophysical models, and from Brownian dynamics simulations of diffusion in multi-scale structures.
650 2 4 $a Numerical and Computational Physics. $3 768904
650 2 4 $a Cell Biology. $3 593889
650 2 4 $a Mathematical and Computational Biology. $3 786706
650 2 4 $a Biophysics and Biological Physics. $3 768559
650 1 4 $a Physics. $3 564049
650 0 $a Cytology. $3 599554
650 0 $a Molecular biology. $3 583443
650 0 $a Stochastic processes. $3 528256
700 1 $a Schuss, Zeev. $3 888930
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-1-4939-3103-3
950 $a Physics and Astronomy (Springer-11651)