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Non-neuronal mechanisms of brain damage and repair after stroke

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Non-neuronal mechanisms of brain damage and repair after stroke/ edited by Jun Chen, John H. Zhang, Xiaoming Hu.
other author:	Chen, Jun.
Published:	Cham :Springer International Publishing : : 2016.,
Description:	xiii, 408 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Cerebrovascular disease - Molecular aspects. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-32337-4
ISBN:	9783319323374

Non-neuronal mechanisms of brain damage and repair after stroke
Non-neuronal mechanisms of brain damage and repair after stroke[electronic resource] /edited by Jun Chen, John H. Zhang, Xiaoming Hu. - Cham :Springer International Publishing :2016. - xiii, 408 p. :ill., digital ;24 cm. - Springer series in translational stroke research,2363-958X. - Springer series in translational stroke research..

Part 1. Microvascular integrity in stroke -- 1. Structural alterations to the endothelial tight junction complex during stroke -- 2. Role of pericytes in neurovascular unite and stroke -- 3. Glial support of blood-brain barrier integrity: Molecular targets for novel therapeutic strategies in stroke -- 4. Barrier mechanism in neonatal stroke -- 5. Angiogenesis: a realistic therapy for ischemic stroke -- Part 2. Glial cells in stroke -- 6. Astrocytes as a target for ischemic stroke -- 7. Microglia: a double-sided sword in stroke -- 8. Crosstalk between cerebral endothelium and oligodendrocyte after stroke -- Part 3. Peripheral immune cells in stroke -- 9. The peripheral immune response to stroke -- 10. The Role of spleen-derived immune cells in ischemic brain injury -- 11. Regulatory T cells in ischemic brain injury -- 12. B cells in stroke and preconditioning-induced protection against stroke -- 13. Mast cell as an early responder in ischemic brain injury -- 14. Roles of neutrophils in stroke -- 15. The function of cytokines in ischemic stroke -- Part 4. White matter injury and repair in stroke -- 16. Ischemic injury to white matter: an age-dependent process -- 17. Neurovascular repair after stroke -- 18. The role of non-neuronal Nrf2 pathway in ischemic stroke: damage control and potential tissue repair -- 19. Stem cell therapy for ischemic stroke.

This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.

ISBN: 9783319323374

Standard No.: 10.1007/978-3-319-32337-4doiSubjects--Topical Terms:

1112922
Cerebrovascular disease
--Molecular aspects.

LC Class. No.: RC388.5

Dewey Class. No.: 616.81

Non-neuronal mechanisms of brain damage and repair after stroke
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520 $a This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.
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