國立虎尾科技大學 |

Cystogenesis

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Cystogenesis/ edited by Jong Hoon Park, Curie Ahn.
其他作者:	Park, Jong Hoon.
出版者:	Singapore :Springer Singapore : : 2016.,
面頁冊數:	ix, 126 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Polycystic kidney disease. -
電子資源:	http://dx.doi.org/10.1007/978-981-10-2041-4
ISBN:	9789811020414

Cystogenesis
Cystogenesis[electronic resource] /edited by Jong Hoon Park, Curie Ahn. - Singapore :Springer Singapore :2016. - ix, 126 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.9330065-2598 ;. - Advances in experimental medicine and biology ;780..

Part I ADPKD Overview -- Chapter 1 Recent Trends in ADPKD Research -- Chapter 2 Genetic Mechanisms of ADPKD -- Part II Cystogenesis Mechanisms -- Chapter 3 Cell Proliferation and Apoptosis in ADPKD -- Chapter 4 Inflammation and Fibrosis in ADPKD -- Chapter 5 Functional Study of the Primary Cilia in ADPKD -- Chapter 6 Epigenetic Regulation in Cystogenesis -- Part III Therapeutic Approaches and Diagnostic Markers for ADPKD -- Chapter 7 Validation of Effective Therapeutic Targets for ADPKD using Animal Models -- Chapter 8 Diagnostic Evaluation as a Biomarker in Patients with ADPKD -- Chapter 9 Clinical Trials and a View toward the Future of ADPKD.

This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD) ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted therapies for ADPKD currently available, making it important to understand the basic cellular mechanisms underlying the onset and progression of ADPKD, in order to identify potential therapeutic targets for the disease. Several therapeutic approaches that have been attempted to date are reviewed. This work provides a broad overview of ADPKD and highlights the key challenges currently faced by researchers in this field. Furthermore, it provides insight into ADPKD to facilitate the development of novel biomarkers for ADPKD and to direct future research into this challenging pathology. This book is suitable for clinicians who have encountered patients with ADPKD, for clinicians / researchers working in the field of ADPKD and more generally on the kidney and kidney related disorders and for students of medicine with an interest in internal medicine.

ISBN: 9789811020414

Standard No.: 10.1007/978-981-10-2041-4doiSubjects--Topical Terms:

1114465
Polycystic kidney disease.

LC Class. No.: RC918.P58

Dewey Class. No.: 616.61

Cystogenesis
LDR:02909nam a2200325 a 4500 001 867526
003 DE-He213
005 20161012041346.0
006 m d
007 cr nn 008maaau
008 170720s2016 si s 0 eng d
020 $a 9789811020414 $q (electronic bk.)
020 $a 9789811020407 $q (paper)
024 7 $a 10.1007/978-981-10-2041-4 $2 doi
035 $a 978-981-10-2041-4
040 $a GP $c GP
041 0 $a eng
050 4 $a RC918.P58
072 7 $a MFN $2 bicssc
072 7 $a MED107000 $2 bisacsh
082 0 4 $a 616.61 $2 23
090 $a RC918.P58 $b C997 2016
245 0 0 $a Cystogenesis $h [electronic resource] / $c edited by Jong Hoon Park, Curie Ahn.
260 $a Singapore : $c 2016. $b Springer Singapore : $b Imprint: Springer,
300 $a ix, 126 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.933
505 0 $a Part I ADPKD Overview -- Chapter 1 Recent Trends in ADPKD Research -- Chapter 2 Genetic Mechanisms of ADPKD -- Part II Cystogenesis Mechanisms -- Chapter 3 Cell Proliferation and Apoptosis in ADPKD -- Chapter 4 Inflammation and Fibrosis in ADPKD -- Chapter 5 Functional Study of the Primary Cilia in ADPKD -- Chapter 6 Epigenetic Regulation in Cystogenesis -- Part III Therapeutic Approaches and Diagnostic Markers for ADPKD -- Chapter 7 Validation of Effective Therapeutic Targets for ADPKD using Animal Models -- Chapter 8 Diagnostic Evaluation as a Biomarker in Patients with ADPKD -- Chapter 9 Clinical Trials and a View toward the Future of ADPKD.
520 $a This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD) ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted therapies for ADPKD currently available, making it important to understand the basic cellular mechanisms underlying the onset and progression of ADPKD, in order to identify potential therapeutic targets for the disease. Several therapeutic approaches that have been attempted to date are reviewed. This work provides a broad overview of ADPKD and highlights the key challenges currently faced by researchers in this field. Furthermore, it provides insight into ADPKD to facilitate the development of novel biomarkers for ADPKD and to direct future research into this challenging pathology. This book is suitable for clinicians who have encountered patients with ADPKD, for clinicians / researchers working in the field of ADPKD and more generally on the kidney and kidney related disorders and for students of medicine with an interest in internal medicine.
650 0 $a Polycystic kidney disease. $3 1114465
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Human Genetics. $3 593893
650 2 4 $a Molecular Medicine. $3 668353
650 2 4 $a Cell Biology. $3 593889
650 2 4 $a Medical Microbiology. $3 668401
700 1 $a Park, Jong Hoon. $3 1114463
700 1 $a Ahn, Curie. $3 1114464
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v 780. $3 881230
856 4 0 $u http://dx.doi.org/10.1007/978-981-10-2041-4
950 $a Biomedical and Life Sciences (Springer-11642)