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Histamine receptors = preclinical and clinical aspects /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Histamine receptors/ edited by Patrizio Blandina, Maria Beatrice Passani.
其他題名:	preclinical and clinical aspects /
其他作者:	Blandina, Patrizio.
出版者:	Cham :Springer International Publishing : : 2016.,
面頁冊數:	xiv, 373 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Histamine - Receptors. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-40308-3
ISBN:	9783319403083

Histamine receptors = preclinical and clinical aspects /
Histamine receptorspreclinical and clinical aspects /[electronic resource] :edited by Patrizio Blandina, Maria Beatrice Passani. - Cham :Springer International Publishing :2016. - xiv, 373 p. :ill., digital ;24 cm. - The receptors ;v.28. - Receptors ;v.28..

Molecular aspects of histamine receptors -- Genetic polymorphisms in the histamine receptor family -- The role of the histamine H4 receptor in asthma and atopic dermatitis -- Identification and roles of zebrafish histamine receptors -- Histamine H3r antagonists: from scaffold hopping to clinical candidates -- Clinical significance of histamine H1 receptor gene expression and drug action of antihistamines -- Histamine and its receptors as a module of the biogenic amine diseasome -- Histaminergic regulation of blood-brain barrier activity -- Histamine function in nervous systems -- Heterogeneity of histaminergic neurons -- Modulation by histamine H3 receptors of neurotransmitter release in the basal ganglia -- Interaction of brain histaminergic and dopaminergic systems -- Histamine H1 Receptor Occupancy in Human Brain Measured by Positron Emission Tomography -- Modulation of memory consolidation and extinction by brain histamine -- Histamine and appetite.

A comprehensive and detailed overview of the current state of preclinical research on histamine and histamine receptors. Part of the book focuses on novel approaches to the study of histamine receptors such as polymorphism, genetic linkage, and computational analysis, and on the use of new histaminergic ligands in diseases such as asthma and dermatitis. Several chapters will be devoted to the role of histamine in the control of homeostatic and behavioral responses such as the sleep-wake cycle, regulation of the blood brain barrier, food intake, alertness, itch, and memory formation and consolidation.

ISBN: 9783319403083

Standard No.: 10.1007/978-3-319-40308-3doiSubjects--Topical Terms:

970220
Histamine
--Receptors.

LC Class. No.: QP801.H5

Dewey Class. No.: 572.696

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505 0 $a Molecular aspects of histamine receptors -- Genetic polymorphisms in the histamine receptor family -- The role of the histamine H4 receptor in asthma and atopic dermatitis -- Identification and roles of zebrafish histamine receptors -- Histamine H3r antagonists: from scaffold hopping to clinical candidates -- Clinical significance of histamine H1 receptor gene expression and drug action of antihistamines -- Histamine and its receptors as a module of the biogenic amine diseasome -- Histaminergic regulation of blood-brain barrier activity -- Histamine function in nervous systems -- Heterogeneity of histaminergic neurons -- Modulation by histamine H3 receptors of neurotransmitter release in the basal ganglia -- Interaction of brain histaminergic and dopaminergic systems -- Histamine H1 Receptor Occupancy in Human Brain Measured by Positron Emission Tomography -- Modulation of memory consolidation and extinction by brain histamine -- Histamine and appetite.
520 $a A comprehensive and detailed overview of the current state of preclinical research on histamine and histamine receptors. Part of the book focuses on novel approaches to the study of histamine receptors such as polymorphism, genetic linkage, and computational analysis, and on the use of new histaminergic ligands in diseases such as asthma and dermatitis. Several chapters will be devoted to the role of histamine in the control of homeostatic and behavioral responses such as the sleep-wake cycle, regulation of the blood brain barrier, food intake, alertness, itch, and memory formation and consolidation.
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