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Brain lipids in synaptic function an...

Yahi, Nouara, (1964-)

Brain lipids in synaptic function and neurological disease : = clues to innovative therapeutic strategies for brain disorders /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Brain lipids in synaptic function and neurological disease :/ Jacques Fantini, Nouara Yahi.
Reminder of title:	clues to innovative therapeutic strategies for brain disorders /
Author:	Fantini, J.
other author:	Yahi, Nouara,
Published:	London :Elsevier/Academic Press, : 2015.,
Description:	xv, 381 p. :col. ill., ports ; : 25 cm.;
Subject:	Brain - Diseases -
ISBN:	9780128001110 (hbk.) :

Brain lipids in synaptic function and neurological disease : = clues to innovative therapeutic strategies for brain disorders /
Fantini, J.

Brain lipids in synaptic function and neurological disease :clues to innovative therapeutic strategies for brain disorders /Jacques Fantini, Nouara Yahi. - London :Elsevier/Academic Press,2015. - xv, 381 p. :col. ill., ports ;25 cm.

Includes bibliographical references and index.

Chemical basis of lipid biochemistry -- Brain membranes -- Lipid metabolism and oxidation in neurons and glial cells -- Variations of brain lipid content -- A molecular view of the synapse -- Protein-lipid interactions in the brain -- Lipid regulation of receptor function -- Common mechanisms in neurodegenerative diseases -- Creutzfeldt-Jakob disease -- Parkinsons disease -- Alzheimers disease -- Viral and bacterial diseases -- A unifying theory -- Therapeutic strategies for neurodegenerative diseases.

"Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders"--

ISBN: 9780128001110 (hbk.) :NT3811

LCCN: 2015932537Subjects--Topical Terms:

1127649
Brain
--Diseases

LC Class. No.: RC386 / .F36 2015

Dewey Class. No.: 612.8/2

National Library of Medicine Call No.: 2015 I-197

Brain lipids in synaptic function and neurological disease : = clues to innovative therapeutic strategies for brain disorders /
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245 1 0 $a Brain lipids in synaptic function and neurological disease : $b clues to innovative therapeutic strategies for brain disorders / $c Jacques Fantini, Nouara Yahi.
260 # $a London : $b Elsevier/Academic Press, $c 2015.
300 $a xv, 381 p. : $b col. ill., ports ; $c 25 cm.
504 $a Includes bibliographical references and index.
505 0 # $a Chemical basis of lipid biochemistry -- Brain membranes -- Lipid metabolism and oxidation in neurons and glial cells -- Variations of brain lipid content -- A molecular view of the synapse -- Protein-lipid interactions in the brain -- Lipid regulation of receptor function -- Common mechanisms in neurodegenerative diseases -- Creutzfeldt-Jakob disease -- Parkinsons disease -- Alzheimers disease -- Viral and bacterial diseases -- A unifying theory -- Therapeutic strategies for neurodegenerative diseases.
520 # $a "Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders"-- $c Back cover.
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650 2 2 $a Lipid Metabolism. $3 591496
650 2 2 $a Synaptic Transmission. $3 789064
650 2 2 $a Membrane Microdomains. $3 1127650
700 1 # $a Yahi, Nouara, $d 1964- $3 1127648