國立虎尾科技大學 |

Translating molecules into medicines = cross-functional integration at the drug discovery-development interface /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Translating molecules into medicines/ edited by Shobha N. Bhattachar ... [et al.].
Reminder of title:	cross-functional integration at the drug discovery-development interface /
other author:	Bhattachar, Shobha N.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	xxiv, 461 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Drug development. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-50042-3
ISBN:	9783319500423

Translating molecules into medicines = cross-functional integration at the drug discovery-development interface /
Translating molecules into medicinescross-functional integration at the drug discovery-development interface /[electronic resource] :edited by Shobha N. Bhattachar ... [et al.]. - Cham :Springer International Publishing :2017. - xxiv, 461 p. :ill. (some col.), digital ;24 cm. - AAPS advances in the pharmaceutical sciences series,v.252210-7371 ;. - AAPS advances in the pharmaceutical sciences series ;3..

Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases, drug discovery, and drug development. Laying out the detailed trends from various fields, different chapters are dedicated to target engagement, toxicological safety assessments, and the compelling relationship of optimizing early clinical studies with design strategies. The book also highlights the importance of balancing the three pillars: sufficient efficacy, acceptable safety and appropriate pharmacokinetics, all of which are crucial to successful efforts in discovery and development. With discussions regarding the combined approaches of molecular research, personalized medicine, pre-clinical and clinical development, as well as targeted therapies--this compendium is a flexible fit, perfect for professionals in the pharmaceutical industry and related academic fields.

ISBN: 9783319500423

Standard No.: 10.1007/978-3-319-50042-3doiSubjects--Topical Terms:

581824
Drug development.

LC Class. No.: RM301.25

Dewey Class. No.: 615.19

Translating molecules into medicines = cross-functional integration at the drug discovery-development interface /
LDR:02204nam a2200313 a 4500 001 884497
003 DE-He213
005 20170421151030.0
006 m d
007 cr nn 008maaau
008 180530s2017 gw s 0 eng d
020 $a 9783319500423 $q (electronic bk.)
020 $a 9783319500409 $q (paper)
024 7 $a 10.1007/978-3-319-50042-3 $2 doi
035 $a 978-3-319-50042-3
040 $a GP $c GP
041 0 $a eng
050 4 $a RM301.25
072 7 $a TDCW $2 bicssc
072 7 $a MED072000 $2 bisacsh
082 0 4 $a 615.19 $2 23
090 $a RM301.25 $b .T772 2017
245 0 0 $a Translating molecules into medicines $h [electronic resource] : $b cross-functional integration at the drug discovery-development interface / $c edited by Shobha N. Bhattachar ... [et al.].
260 $a Cham : $c 2017. $b Springer International Publishing : $b Imprint: Springer,
300 $a xxiv, 461 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a AAPS advances in the pharmaceutical sciences series, $x 2210-7371 ; $v v.25
520 $a Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases, drug discovery, and drug development. Laying out the detailed trends from various fields, different chapters are dedicated to target engagement, toxicological safety assessments, and the compelling relationship of optimizing early clinical studies with design strategies. The book also highlights the importance of balancing the three pillars: sufficient efficacy, acceptable safety and appropriate pharmacokinetics, all of which are crucial to successful efforts in discovery and development. With discussions regarding the combined approaches of molecular research, personalized medicine, pre-clinical and clinical development, as well as targeted therapies--this compendium is a flexible fit, perfect for professionals in the pharmaceutical industry and related academic fields.
650 0 $a Drug development. $3 581824
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Pharmaceutical Sciences/Technology. $3 768561
700 1 $a Bhattachar, Shobha N. $3 1140960
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a AAPS advances in the pharmaceutical sciences series ; $v 3. $3 889162
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-50042-3
950 $a Biomedical and Life Sciences (Springer-11642)