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Multiparticulate drug delivery = formulation, processing and manufacturing /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Multiparticulate drug delivery/ edited by Ali R. Rajabi-Siahboomi.
其他題名:	formulation, processing and manufacturing /
其他作者:	Rajabi-Siahboomi, Ali R.
出版者:	New York, NY :Springer New York : : 2017.,
面頁冊數:	xii, 396 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Drug delivery systems. -
電子資源:	http://dx.doi.org/10.1007/978-1-4939-7012-4
ISBN:	9781493970124

Multiparticulate drug delivery = formulation, processing and manufacturing /
Multiparticulate drug deliveryformulation, processing and manufacturing /[electronic resource] :edited by Ali R. Rajabi-Siahboomi. - New York, NY :Springer New York :2017. - xii, 396 p. :ill. (some col.), digital ;24 cm. - Advances in delivery science and technology,2192-6204. - Advances in delivery science and technology..

Overview of multiparticulates -- Characterization of inert pellets for drug layering -- The science and practice of extrusion-spheronization -- Fluid bed technology, process robustness and scale-up -- Solution and suspension drug layering on inert pellets -- Dry powder layering on pellets Mini-tabs; versatile multiparticulate options for oral drug delivery -- Science and practice of microencapsulation technology -- Use of multiparticulate systems for fixed dose combination drug delivery -- Dissolution testing consideration of multiparticulate system -- Taste masking of multiparticulate systems -- Multiparticulate systems for pediatrics -- Application of methacrylic acid copolymers polymers for oral multiparticulate drug delivery -- Ethylcellulose applications on multiparticulate dosage forms -- Multi-unit particulate systems (MUPS) -- In-line particle size characterization of multipartuclate systems -- In-vivo characterization of multiparticulate systems.

Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

ISBN: 9781493970124

Standard No.: 10.1007/978-1-4939-7012-4doiSubjects--Topical Terms:

581921
Drug delivery systems.

LC Class. No.: RS199.5

Dewey Class. No.: 615.6

Multiparticulate drug delivery = formulation, processing and manufacturing /
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520 $a Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.
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