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Behavioral neuroscience of Orexin/Hypocretin

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Behavioral neuroscience of Orexin/Hypocretin/ edited by Andrew J Lawrence, Luis de Lecea.
other author:	Lawrence, Andrew J.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	viii, 322 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Orexins. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-57535-3
ISBN:	9783319575353

Behavioral neuroscience of Orexin/Hypocretin
Behavioral neuroscience of Orexin/Hypocretin[electronic resource] /edited by Andrew J Lawrence, Luis de Lecea. - Cham :Springer International Publishing :2017. - viii, 322 p. :ill., digital ;24 cm. - Current topics in behavioral neurosciences,v.331866-3370 ;. - Current topics in behavioral neurosciences ;12..

The Human Orexin/Hypocretin Receptor Crystal Structures -- Orexin/Hypocretin Signaling -- Orexin/Hypocretin and Organizing Principles for a Diversity of Wake-Promoting Neurons in the Brain -- The Hypocretin/Orexin Neuronal Networks in Zebrafish -- Hypocretins and Arousal -- Orexin OX 2 Receptor Antagonists as Sleep Aids -- Roles for Orexin/Hypocretin in the Control of Energy Balance and Metabolism -- Orexin and Central Modulation of Cardiovascular and Respiratory Function -- Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders -- The Role of Orexins/Hypocretins in Alcohol Use and Abuse -- A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?- Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse.

This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians.

ISBN: 9783319575353

Standard No.: 10.1007/978-3-319-57535-3doiSubjects--Topical Terms:

668555
Orexins.

LC Class. No.: QP572.O74

Dewey Class. No.: 612.405

Behavioral neuroscience of Orexin/Hypocretin
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505 0 $a The Human Orexin/Hypocretin Receptor Crystal Structures -- Orexin/Hypocretin Signaling -- Orexin/Hypocretin and Organizing Principles for a Diversity of Wake-Promoting Neurons in the Brain -- The Hypocretin/Orexin Neuronal Networks in Zebrafish -- Hypocretins and Arousal -- Orexin OX 2 Receptor Antagonists as Sleep Aids -- Roles for Orexin/Hypocretin in the Control of Energy Balance and Metabolism -- Orexin and Central Modulation of Cardiovascular and Respiratory Function -- Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders -- The Role of Orexins/Hypocretins in Alcohol Use and Abuse -- A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?- Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse.
520 $a This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians.
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