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Heart failure

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Heart failure/ edited by Johann Bauersachs, Javed Butler, Peter Sandner.
other author:	Bauersachs, Johann.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	ix, 581 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Heart failure. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-59659-4
ISBN:	9783319596594

Heart failure
Heart failure[electronic resource] /edited by Johann Bauersachs, Javed Butler, Peter Sandner. - Cham :Springer International Publishing :2017. - ix, 581 p. :ill., digital ;24 cm. - Handbook of experimental pharmacology,v.2430171-2004 ;. - Handbook of experimental pharmacology ;v.212..

Introduction -- Epidemiology -- Clinical trial design, endpoints and regulatory requirements. Biomarkers HFpEF/HFrEF. Imaging Technologies / MRI and Echo. Comorbidities in HF. Current Guideline based therapy of HFreF and HFpEF. New and Emerging Therapies and Targets. Ivabradine -- Beta3 agonists -- Novel MRAs -- pGCs and Natriuretic peptides -- sGC stimulators -- PDE's -- Adenosin and A1 Agonists -- Myosin heavy chain / Troponin -- Stem cells -- Diuretics and Vasopressin -- GeneTherapy -- RNA-based therapies and micro RNAs -- Cardiac myosin activation using gene therapy -- Bendavia - mitochondrial therapies -- WNT signaling -- Anticoagulation therapy and NOACS in HF -- Potassium Binders -- Iron.

This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and biomarkers, as well as imaging technologies. The main focus of this book is to review current and emerging heart failure therapies and potential targets for treatment.

ISBN: 9783319596594

Standard No.: 10.1007/978-3-319-59659-4doiSubjects--Topical Terms:

680169
Heart failure.

LC Class. No.: RC681 / .H43 2017

Dewey Class. No.: 616.12

Heart failure
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505 0 $a Introduction -- Epidemiology -- Clinical trial design, endpoints and regulatory requirements. Biomarkers HFpEF/HFrEF. Imaging Technologies / MRI and Echo. Comorbidities in HF. Current Guideline based therapy of HFreF and HFpEF. New and Emerging Therapies and Targets. Ivabradine -- Beta3 agonists -- Novel MRAs -- pGCs and Natriuretic peptides -- sGC stimulators -- PDE's -- Adenosin and A1 Agonists -- Myosin heavy chain / Troponin -- Stem cells -- Diuretics and Vasopressin -- GeneTherapy -- RNA-based therapies and micro RNAs -- Cardiac myosin activation using gene therapy -- Bendavia - mitochondrial therapies -- WNT signaling -- Anticoagulation therapy and NOACS in HF -- Potassium Binders -- Iron.
520 $a This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and biomarkers, as well as imaging technologies. The main focus of this book is to review current and emerging heart failure therapies and potential targets for treatment.
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