國立虎尾科技大學 |

Patient-derived xenograft models of human cancer

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Patient-derived xenograft models of human cancer/ edited by Yuzhuo Wang, Dong Lin, Peter W. Gout.
其他作者:	Wang, Yuzhuo.
出版者:	Cham :Springer International Publishing : : 2017.,
面頁冊數:	xi, 204 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Cancer - Simulation methods. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-55825-7
ISBN:	9783319558257

Patient-derived xenograft models of human cancer
Patient-derived xenograft models of human cancer[electronic resource] /edited by Yuzhuo Wang, Dong Lin, Peter W. Gout. - Cham :Springer International Publishing :2017. - xi, 204 p. :ill., digital ;24 cm. - Molecular and translational medicine,2197-7852. - Molecular and translational medicine..

Introduction -- History and Evolution of PDX Cancer Models -- Establishment and Characterization of PDX Models -- Methods of Generating PDX Models -- Fidelity and Stability of PDX Models -- Applications of PDX Models -- Studies of Cancer Heterogeneity -- PDX and Cancer Stem Cells -- Modeling Cancer Metastasis -- Modeling Drug Resistance -- PDX and Biomarker Development -- PDX and Preclinical Drug Screening -- Co-clinical Trials and Personalized Cancer Therapy/Precision Medicine -- Epilogue -- Future Perspective.

This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provide a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions. Extensive illustrations make this an interactive text. Patient-Derived Xenograft Models of Human Cancer will serve as a highly useful resource for researchers and clinicians dealing with, or interested in, this important topic. It will provide a concise yet comprehensive summary of the current status of the field that will help guide preclinical and clinical applications as well as stimulate investigative efforts. This book will propagate innovative concepts and prompt the development of ground-breaking technological solutions in this field.

ISBN: 9783319558257

Standard No.: 10.1007/978-3-319-55825-7doiSubjects--Topical Terms:

1173344
Cancer
--Simulation methods.

LC Class. No.: RC267

Dewey Class. No.: 616.9940011

Patient-derived xenograft models of human cancer
LDR:02732nam a2200325 a 4500 001 905892
003 DE-He213
005 20180104135358.0
006 m d
007 cr nn 008maaau
008 190308s2017 gw s 0 eng d
020 $a 9783319558257 $q (electronic bk.)
020 $a 9783319558240 $q (paper)
024 7 $a 10.1007/978-3-319-55825-7 $2 doi
035 $a 978-3-319-55825-7
040 $a GP $c GP
041 0 $a eng
050 4 $a RC267
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
082 0 4 $a 616.9940011 $2 23
090 $a RC267 $b .P298 2017
245 0 0 $a Patient-derived xenograft models of human cancer $h [electronic resource] / $c edited by Yuzhuo Wang, Dong Lin, Peter W. Gout.
260 $a Cham : $c 2017. $b Springer International Publishing : $b Imprint: Humana Press,
300 $a xi, 204 p. : $b ill., digital ; $c 24 cm.
490 1 $a Molecular and translational medicine, $x 2197-7852
505 0 $a Introduction -- History and Evolution of PDX Cancer Models -- Establishment and Characterization of PDX Models -- Methods of Generating PDX Models -- Fidelity and Stability of PDX Models -- Applications of PDX Models -- Studies of Cancer Heterogeneity -- PDX and Cancer Stem Cells -- Modeling Cancer Metastasis -- Modeling Drug Resistance -- PDX and Biomarker Development -- PDX and Preclinical Drug Screening -- Co-clinical Trials and Personalized Cancer Therapy/Precision Medicine -- Epilogue -- Future Perspective.
520 $a This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provide a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions. Extensive illustrations make this an interactive text. Patient-Derived Xenograft Models of Human Cancer will serve as a highly useful resource for researchers and clinicians dealing with, or interested in, this important topic. It will provide a concise yet comprehensive summary of the current status of the field that will help guide preclinical and clinical applications as well as stimulate investigative efforts. This book will propagate innovative concepts and prompt the development of ground-breaking technological solutions in this field.
650 0 $a Cancer $x Simulation methods. $3 1173344
650 0 $a Cancer $x Research. $3 783845
650 1 4 $a Medicine & Public Health. $3 593949
650 2 4 $a Oncology. $3 593951
700 1 $a Wang, Yuzhuo. $3 1173341
700 1 $a Lin, Dong. $3 1173342
700 1 $a Gout, Peter W. $3 1173343
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Molecular and translational medicine. $3 884289
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-55825-7
950 $a Medicine (Springer-11650)