國立虎尾科技大學 |

Rapid cell magnetisation using cationised magnetoferritin

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Rapid cell magnetisation using cationised magnetoferritin/ by Sara Correia Carreira.
作者:	Carreira, Sara Correia.
出版者:	Cham :Springer International Publishing : : 2017.,
面頁冊數:	xvii, 166 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
標題:	Biophysics. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-60333-9
ISBN:	9783319603339

Rapid cell magnetisation using cationised magnetoferritin
Carreira, Sara Correia.

Rapid cell magnetisation using cationised magnetoferritin[electronic resource] /by Sara Correia Carreira. - Cham :Springer International Publishing :2017. - xvii, 166 p. :ill., digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

Introduction -- Materials and Methods -- Characterising Magnetoferritin and Cationised Magnetoferritin -- Stem Cell Labelling with Cationised Magnetoferritin -- Toxicological Profiling of Cationised Magnetoferritin -- Escherichia coli labelling with Cationised Magnetoferritin -- Overall Conclusions and Future Opportunities.

Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.

ISBN: 9783319603339

Standard No.: 10.1007/978-3-319-60333-9doiSubjects--Topical Terms:

581576
Biophysics.

LC Class. No.: QH505

Dewey Class. No.: 571.47

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520 $a Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.
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