國立虎尾科技大學 |

Development and Experimental Validation of Mathematical Tools for Computerized Monitoring of Cryosurgery.

紀錄類型:	書目-語言資料,手稿 : Monograph/item
正題名/作者:	Development and Experimental Validation of Mathematical Tools for Computerized Monitoring of Cryosurgery./
作者:	Thaokar, Chandrajit.
面頁冊數:	1 online resource (104 pages)
附註:	Source: Dissertation Abstracts International, Volume: 78-05(E), Section: B.
Contained By:	Dissertation Abstracts International78-05B(E).
標題:	Mechanical engineering. -
電子資源:	click for full text (PQDT)
ISBN:	9781369292398

Development and Experimental Validation of Mathematical Tools for Computerized Monitoring of Cryosurgery.
Thaokar, Chandrajit.

Development and Experimental Validation of Mathematical Tools for Computerized Monitoring of Cryosurgery. - 1 online resource (104 pages)

Source: Dissertation Abstracts International, Volume: 78-05(E), Section: B.

Thesis (Ph.D.)

Includes bibliographical references

Cryosurgery is the destruction of undesired biological tissues by freezing. Modern cryosurgery is frequently performed as a minimally-invasive procedure, where multiple hypodermic, needle-shaped cryoprobes are inserted into the target area to be treated. The aim of the cryosurgeon is to maximize cryoinjury within a target region, while minimizing damage to healthy surrounding tissues. There is an undisputed need for temperature-field reconstruction during minimally invasive cryosurgery to help the cryosurgeon achieve this aim.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9781369292398Subjects--Topical Terms:

557493
Mechanical engineering.
Index Terms--Genre/Form:

554714
Electronic books.

Development and Experimental Validation of Mathematical Tools for Computerized Monitoring of Cryosurgery.
LDR:04241ntm a2200373Ki 4500 001 909529
005 20180426100013.5
006 m o u
007 cr mn||||a|a||
008 190606s2016 xx obm 000 0 eng d
020 $a 9781369292398
035 $a (MiAaPQ)AAI10179144
035 $a (MiAaPQ)cmu:10026
035 $a AAI10179144
040 $a MiAaPQ $b eng $c MiAaPQ
099 $a TUL $f hyy $c available through World Wide Web
100 1 $a Thaokar, Chandrajit. $3 1180355
245 1 0 $a Development and Experimental Validation of Mathematical Tools for Computerized Monitoring of Cryosurgery.
264 0 $c 2016
300 $a 1 online resource (104 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Dissertation Abstracts International, Volume: 78-05(E), Section: B.
500 $a Adviser: Yoed Rabin.
502 $a Thesis (Ph.D.) $c Carnegie Mellon University $d 2016.
504 $a Includes bibliographical references
520 $a Cryosurgery is the destruction of undesired biological tissues by freezing. Modern cryosurgery is frequently performed as a minimally-invasive procedure, where multiple hypodermic, needle-shaped cryoprobes are inserted into the target area to be treated. The aim of the cryosurgeon is to maximize cryoinjury within a target region, while minimizing damage to healthy surrounding tissues. There is an undisputed need for temperature-field reconstruction during minimally invasive cryosurgery to help the cryosurgeon achieve this aim.
520 $a The work presented in this thesis is a part of ongoing project at the Biothermal Technology Laboratory (BTTL), to develop hardware and software tools to accomplish real-time temperature field reconstruction. The goal in this project is two-fold: (i) to develop the hardware necessary for miniature, wireless, implantable temperature sensors, and (ii) to develop mathematical techniques for temperature-field reconstruction in real time, which is the focus of the work presented in this thesis. To accomplish this goal, this study proposes a computational approach for real-time temperature-field reconstruction, combining data obtained from various sensing modalities such as medical imaging, cryoprobe-embedded sensors, and miniature, wireless, implantable sensors. In practice, the proposed approach aims at solving the inverse bioheat transfer problem during cryosurgery, where spatially distributed input data is used to reconstruct the temperature field.
520 $a Three numerical methods have been developed and are evaluated in the scope of this thesis. The first is based on a quasi-steady approximation of the transient temperature field, which has been termed Temperature Field Reconstruction Method (TFRM). The second method is based on analogy between the fields of temperature and electrical potential, and is thus termed Potential Field Analogy Method (PFAM). The third method is essentially a hybrid of TFRM and PFAM, which has shown superior results. Each of these methods has been benchmarked against a full-scale finite elements analysis using the commercial code ANSYS. Benchmarking results display an average mismatch of less than 2 mm in 2D cases and less than 3 mm in 3D cases for the location of the clinically significance isotherms of -22°C and -45°C.
520 $a In an advanced stage of numerical methods evaluation, they have been validated against experimental data, previously obtained at the BTTL. Those experiments were conducted on a gelatin solution, using proprietary liquid-nitrogen cryoprobes and a cryoheater to simulate urethral warming. The design of the experiment was aimed at creating a 2D heat-transfer problem. Validation results against experimental data suggest an average mismatch of less than 2 mm, for the hybrid of TFRM + PFAM method, which is of the order of uncertainty in estimating the freezing front location based on ultrasound imaging.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Mechanical engineering. $3 557493
655 7 $a Electronic books. $2 local $3 554714
690 $a 0548
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a Carnegie Mellon University. $b Mechanical Engineering. $3 1148639
773 0 $t Dissertation Abstracts International $g 78-05B(E).
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10179144 $z click for full text (PQDT)