國立虎尾科技大學 |

Micro-Particle Operations Using Asymmetric Traps.

紀錄類型:	書目-語言資料,手稿 : Monograph/item
正題名/作者:	Micro-Particle Operations Using Asymmetric Traps./
作者:	Lee, Jae Sung.
面頁冊數:	1 online resource (119 pages)
附註:	Source: Dissertation Abstracts International, Volume: 79-04(E), Section: B.
Contained By:	Dissertation Abstracts International79-04B(E).
標題:	Chemical engineering. -
電子資源:	click for full text (PQDT)
ISBN:	9780355365962

Micro-Particle Operations Using Asymmetric Traps.
Lee, Jae Sung.

Micro-Particle Operations Using Asymmetric Traps. - 1 online resource (119 pages)

Source: Dissertation Abstracts International, Volume: 79-04(E), Section: B.

Thesis (Ph.D.)

Includes bibliographical references

Micro-particles are a great tool to detect biomolecules for their high multiplexing capability, wide options of materials, and scalability. Currently, most of the platforms utilizing micro-particles are bench-top scale instruments equipped with bulky devices for fine spatiotemporal control of micro-particles. This requirement for resources restricts the environment where micro-particles can be applied. To this problem, microfluidic techniques are an attractive solution because of its inherent capability of fine controlling of micro-particle due to scale matching.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9780355365962Subjects--Topical Terms:

555952
Chemical engineering.
Index Terms--Genre/Form:

554714
Electronic books.

Micro-Particle Operations Using Asymmetric Traps.
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245 1 0 $a Micro-Particle Operations Using Asymmetric Traps.
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300 $a 1 online resource (119 pages)
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500 $a Source: Dissertation Abstracts International, Volume: 79-04(E), Section: B.
500 $a Adviser: Mark A Burns.
502 $a Thesis (Ph.D.) $c University of Michigan $d 2017.
504 $a Includes bibliographical references
520 $a Micro-particles are a great tool to detect biomolecules for their high multiplexing capability, wide options of materials, and scalability. Currently, most of the platforms utilizing micro-particles are bench-top scale instruments equipped with bulky devices for fine spatiotemporal control of micro-particles. This requirement for resources restricts the environment where micro-particles can be applied. To this problem, microfluidic techniques are an attractive solution because of its inherent capability of fine controlling of micro-particle due to scale matching.
520 $a This dissertation describes the development of the micro-particle operations using the asymmetric trap, a new mechanical trap that has flow direction dependent particle capturing behavior. Based on the theory of deterministic lateral displacement of microparticle in periodic obstacle array and mass balance relationships, we provide a model that connects characteristic trap-particle interactions to critical dimensions including particle diameter and the gaps of the asymmetric traps. We theoretically predicted and experimentally observed five different trap-particle interactions including one-way particle transport, symmetric passage, symmetric capturing, trap skipping in zig-zag mode, and trap skipping in bump mode. Our model could explain most of the experimental results (particle diameter = 20.3 mum, Re < 0.01).
520 $a Based on our modeling of particle dynamics in the asymmetric traps, we explore micro-particle operations using the asymmetric traps. One-way particle transport, the basic transport function using asymmetric traps, could displace hundreds of microparticles across trap rows in only a few fluid oscillations (<500 ms per oscillation). On top of that, the segregation, medium exchange, and focusing and splitting of microparticle in oscillatory flow were accomplished by capitalizing on two features: difference in the transport speeds of the trap-particle interaction dynamics and transport polarity of the asymmetric traps. At first, segregation of micro-particle mixture was achieved by utilizing the difference in transport speeds of trap-particle interaction dynamics. In the investigation of factors of the segregation performance, we found that the number of rows is the critical factor for a high performance of the segregation. Next, medium exchange of the particles in oscillatory flow was successfully demonstrated. At modest amplitude and number of fluid oscillations, the particle could be displaced into a new medium over the mixing region. Lastly, we could focus and split of groups of micro-particles in a few fluid oscillations by exploiting transport polarity of the asymmetric traps.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Chemical engineering. $3 555952
655 7 $a Electronic books. $2 local $3 554714
690 $a 0542
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a University of Michigan. $b Chemical Engineering. $3 1181977
773 0 $t Dissertation Abstracts International $g 79-04B(E).
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10670342 $z click for full text (PQDT)