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Environmental Thyroid Endocrine Disr...
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ProQuest Information and Learning Co.
Environmental Thyroid Endocrine Disruption in Shiner Perch (Cymatogaster aggregata) : = An Analysis of Thyroid Glandular Function.
紀錄類型:
書目-語言資料,手稿 : Monograph/item
正題名/作者:
Environmental Thyroid Endocrine Disruption in Shiner Perch (Cymatogaster aggregata) :/
其他題名:
An Analysis of Thyroid Glandular Function.
作者:
Lee, Evan B.
面頁冊數:
1 online resource (57 pages)
附註:
Source: Masters Abstracts International, Volume: 57-01.
Contained By:
Masters Abstracts International57-01(E).
標題:
Endocrinology. -
電子資源:
click for full text (PQDT)
ISBN:
9780355252255
Environmental Thyroid Endocrine Disruption in Shiner Perch (Cymatogaster aggregata) : = An Analysis of Thyroid Glandular Function.
Lee, Evan B.
Environmental Thyroid Endocrine Disruption in Shiner Perch (Cymatogaster aggregata) :
An Analysis of Thyroid Glandular Function. - 1 online resource (57 pages)
Source: Masters Abstracts International, Volume: 57-01.
Thesis (M.S.)
Includes bibliographical references
Industrialized and developed urban centers surround the aquatic ecosystem of San Francisco Bay, and are historic and current sources of anthropogenic contaminants to which resident wildlife is exposed and impacted. An indigenous fish species, the shiner perch (Cymatogaster aggregata), was demonstrated to exhibit significant reductions in plasma tetraiodothyronine (T4) concentrations when sampled from highly industrial Oakland Inner Harbor (OAK) as compared with less impacted locations like Redwood City (RED). This study combined histomorphological evaluation of thyroid follicular tissues and characterization of plasma thyroid hormones, T4 and triiodothyronine (T3). Fish from OAK, but not RED, exhibited reduced plasma T4, T3, and total thyroid hormones, changes that were significantly correlated with thyroid glandular changes including reduced follicular colloid sizes. The findings indicate environmental disruption of thyroid hormone biosynthesis and possible thyroid gland compensatory responses (to low thyroid hormone levels) given the reduced colloid volumes.
Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018
Mode of access: World Wide Web
ISBN: 9780355252255Subjects--Topical Terms:
645497
Endocrinology.
Index Terms--Genre/Form:
554714
Electronic books.
Environmental Thyroid Endocrine Disruption in Shiner Perch (Cymatogaster aggregata) : = An Analysis of Thyroid Glandular Function.
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Industrialized and developed urban centers surround the aquatic ecosystem of San Francisco Bay, and are historic and current sources of anthropogenic contaminants to which resident wildlife is exposed and impacted. An indigenous fish species, the shiner perch (Cymatogaster aggregata), was demonstrated to exhibit significant reductions in plasma tetraiodothyronine (T4) concentrations when sampled from highly industrial Oakland Inner Harbor (OAK) as compared with less impacted locations like Redwood City (RED). This study combined histomorphological evaluation of thyroid follicular tissues and characterization of plasma thyroid hormones, T4 and triiodothyronine (T3). Fish from OAK, but not RED, exhibited reduced plasma T4, T3, and total thyroid hormones, changes that were significantly correlated with thyroid glandular changes including reduced follicular colloid sizes. The findings indicate environmental disruption of thyroid hormone biosynthesis and possible thyroid gland compensatory responses (to low thyroid hormone levels) given the reduced colloid volumes.
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