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Breast Cancer Survivors and Medication Adherence : = The Role of Health Beliefs, Perceptions of Aging, and Partner Support.

紀錄類型:	書目-語言資料,手稿 : Monograph/item
正題名/作者:	Breast Cancer Survivors and Medication Adherence :/
其他題名:	The Role of Health Beliefs, Perceptions of Aging, and Partner Support.
作者:	Brier, Moriah Julia.
面頁冊數:	1 online resource (130 pages)
附註:	Source: Dissertation Abstracts International, Volume: 79-01(E), Section: B.
標題:	Clinical psychology. -
電子資源:	click for full text (PQDT)
ISBN:	9780355182378

Breast Cancer Survivors and Medication Adherence : = The Role of Health Beliefs, Perceptions of Aging, and Partner Support.
Brier, Moriah Julia.

Breast Cancer Survivors and Medication Adherence :The Role of Health Beliefs, Perceptions of Aging, and Partner Support. - 1 online resource (130 pages)

Source: Dissertation Abstracts International, Volume: 79-01(E), Section: B.

Thesis (Ph.D.)--University of Pennsylvania, 2017.

Includes bibliographical references

Aromatase inhibitors (AIs) are a daily endocrine therapy for post-menopausal breast cancer survivors and often cause difficult side effects. Women who do not adhere to AI treatment are at higher risk of cancer recurrence and mortality, yet poor adherence is a prevalent problem. This dissertation explores potentially modifiable, psychosocial predictors of AI adherence. In Chapter 1, to determine how to measure adherence in subsequent studies, we examined the psychometric properties of two self-report adherence measures. Using estrogen assays to assess convergent validity, we found that neither measure performed well; however, in exploratory analyses, a "yes/no" item about use of an AI in the past month was found to be associated with estrogen metabolite levels. In Chapter 2, we examined whether survivors' health beliefs about AI treatment predicted their adherence behaviors. Higher perceived barriers to AI treatment, but not perceived susceptibility to cancer recurrence or perceived benefits of AI treatment, predicted non-adherence. In Chapter 3, we examined the role of arthralgia-associated aging perceptions. After controlling for the severity of arthralgia (a common side effect of AIs), we found that the risk of non-adherence was higher among women who perceived that they had aged rapidly while on the treatment. We used a mixed-methods approach in Chapter 4 to examine the role of partner support. Our qualitative findings suggest that integration of partners into follow-up care and partner support around body changes and sexual dysfunction associated with AIs may contribute to women's ability to persist with their treatment. Our quantitative results demonstrated that satisfaction with partner support around AI treatment was determined by affection and emotional support, whereas informational and tangible support had no bearings on their satisfaction levels. Support preferences did not differ between women with lower and higher levels of pain from AI side effects; however, women with higher levels of pain tended to receive more informational support. Together, these findings can inform intervention content for women who are at risk of not adhering to AI treatment.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9780355182378Subjects--Topical Terms:

649607
Clinical psychology.
Index Terms--Genre/Form:

554714
Electronic books.

Breast Cancer Survivors and Medication Adherence : = The Role of Health Beliefs, Perceptions of Aging, and Partner Support.
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500 $a Source: Dissertation Abstracts International, Volume: 79-01(E), Section: B.
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502 $a Thesis (Ph.D.)--University of Pennsylvania, 2017.
504 $a Includes bibliographical references
520 $a Aromatase inhibitors (AIs) are a daily endocrine therapy for post-menopausal breast cancer survivors and often cause difficult side effects. Women who do not adhere to AI treatment are at higher risk of cancer recurrence and mortality, yet poor adherence is a prevalent problem. This dissertation explores potentially modifiable, psychosocial predictors of AI adherence. In Chapter 1, to determine how to measure adherence in subsequent studies, we examined the psychometric properties of two self-report adherence measures. Using estrogen assays to assess convergent validity, we found that neither measure performed well; however, in exploratory analyses, a "yes/no" item about use of an AI in the past month was found to be associated with estrogen metabolite levels. In Chapter 2, we examined whether survivors' health beliefs about AI treatment predicted their adherence behaviors. Higher perceived barriers to AI treatment, but not perceived susceptibility to cancer recurrence or perceived benefits of AI treatment, predicted non-adherence. In Chapter 3, we examined the role of arthralgia-associated aging perceptions. After controlling for the severity of arthralgia (a common side effect of AIs), we found that the risk of non-adherence was higher among women who perceived that they had aged rapidly while on the treatment. We used a mixed-methods approach in Chapter 4 to examine the role of partner support. Our qualitative findings suggest that integration of partners into follow-up care and partner support around body changes and sexual dysfunction associated with AIs may contribute to women's ability to persist with their treatment. Our quantitative results demonstrated that satisfaction with partner support around AI treatment was determined by affection and emotional support, whereas informational and tangible support had no bearings on their satisfaction levels. Support preferences did not differ between women with lower and higher levels of pain from AI side effects; however, women with higher levels of pain tended to receive more informational support. Together, these findings can inform intervention content for women who are at risk of not adhering to AI treatment.
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538 $a Mode of access: World Wide Web
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