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Ambiguous cue interpretation in psychopathology : = Validation and extension of an animal model of cognitive bias.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Ambiguous cue interpretation in psychopathology :/
Reminder of title:	Validation and extension of an animal model of cognitive bias.
Author:	Bolling, Danielle Zalta.
Description:	1 online resource (230 pages)
Notes:	Source: Dissertation Abstracts International, Volume: 78-07(E), Section: B.
Subject:	Cognitive psychology. -
Online resource:	click for full text (PQDT)
ISBN:	9781369619065

Ambiguous cue interpretation in psychopathology : = Validation and extension of an animal model of cognitive bias.
Bolling, Danielle Zalta.

Ambiguous cue interpretation in psychopathology :Validation and extension of an animal model of cognitive bias. - 1 online resource (230 pages)

Source: Dissertation Abstracts International, Volume: 78-07(E), Section: B.

Thesis (Ph.D.)--Yale University, 2016.

Includes bibliographical references

Cognitive theories of psychopathology predict a central role for maladaptive information processing biases, especially in relation to anxiety and depression symptoms. Because of the purported role of negative cognitive biases in the onset and maintenance of these disorders, efforts to improve treatment outcomes have focused on the modification of cognitive biases. However, variability in the methods for measuring cognitive biases has produced a substantial amount of discrepant results regarding the detailed relationship between biased cognitions and symptomatology. Furthermore, a reliance on complex methods that are only applicable in human populations occludes the translation of these studies to animal research. The current dissertation focused specifically on interpretation biases in relation to anxiety and depression symptom variability in a non-clinical adult sample. We utilized an ambiguous cue interpretation (ACI) task designed to increase translational compatibility between human and animal studies of mental illness. Despite predictions of negative interpretation biases in participants with high self-reported anxiety and depression symptoms, we instead found uniquely unbiased behavior in these individuals (Chapter 2). Unbiased behavior was subsequently associated with greater uncertainty-related neural activation in response to ambiguous task stimuli, measured with functional magnetic resonance imaging (Chapter 3). Furthermore, unbiased behavior that persisted over two months was associated with increased self-reported distress and neural sensitivity to a social stressor (Chapter 4). These results are interpreted as evidence of a role for biased behavior in reducing uncertainty. Unbiased behavior in the current investigation may represent a psychopathology-related failure in strategic decision-making, highlighting the importance of adaptive bias behaviors to psychological well-being.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9781369619065Subjects--Topical Terms:

556029
Cognitive psychology.
Index Terms--Genre/Form:

554714
Electronic books.

Ambiguous cue interpretation in psychopathology : = Validation and extension of an animal model of cognitive bias.
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500 $a Source: Dissertation Abstracts International, Volume: 78-07(E), Section: B.
500 $a Adviser: Kevin A. Pelphrey.
502 $a Thesis (Ph.D.)--Yale University, 2016.
504 $a Includes bibliographical references
520 $a Cognitive theories of psychopathology predict a central role for maladaptive information processing biases, especially in relation to anxiety and depression symptoms. Because of the purported role of negative cognitive biases in the onset and maintenance of these disorders, efforts to improve treatment outcomes have focused on the modification of cognitive biases. However, variability in the methods for measuring cognitive biases has produced a substantial amount of discrepant results regarding the detailed relationship between biased cognitions and symptomatology. Furthermore, a reliance on complex methods that are only applicable in human populations occludes the translation of these studies to animal research. The current dissertation focused specifically on interpretation biases in relation to anxiety and depression symptom variability in a non-clinical adult sample. We utilized an ambiguous cue interpretation (ACI) task designed to increase translational compatibility between human and animal studies of mental illness. Despite predictions of negative interpretation biases in participants with high self-reported anxiety and depression symptoms, we instead found uniquely unbiased behavior in these individuals (Chapter 2). Unbiased behavior was subsequently associated with greater uncertainty-related neural activation in response to ambiguous task stimuli, measured with functional magnetic resonance imaging (Chapter 3). Furthermore, unbiased behavior that persisted over two months was associated with increased self-reported distress and neural sensitivity to a social stressor (Chapter 4). These results are interpreted as evidence of a role for biased behavior in reducing uncertainty. Unbiased behavior in the current investigation may represent a psychopathology-related failure in strategic decision-making, highlighting the importance of adaptive bias behaviors to psychological well-being.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
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