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Mechanisms of Memory Reactivation during Sleep.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Mechanisms of Memory Reactivation during Sleep./
Author:	Antony, James.
Description:	1 online resource (141 pages)
Notes:	Source: Dissertation Abstracts International, Volume: 76-08(E), Section: B.
Subject:	Neurosciences. -
Online resource:	click for full text (PQDT)
ISBN:	9781321633887

Mechanisms of Memory Reactivation during Sleep.
Antony, James.

Mechanisms of Memory Reactivation during Sleep. - 1 online resource (141 pages)

Source: Dissertation Abstracts International, Volume: 76-08(E), Section: B.

Thesis (Ph.D.)--Northwestern University, 2015.

Includes bibliographical references

Repeatedly visiting memories prevents their decay into oblivion. This repetition certainly occurs while a person is awake, but a strong body of evidence shows it also occurs spontaneously during sleep. A fundamental aspect of this idea is that newly formed hippocampal memory traces become reactivated during sleep, suggesting sleep plays an active, qualitatively distinct step in the long-term preservation of memories. Moreover, memory reactivation can apparently be induced during post-learning sleep by presenting stimuli that had previously been associated with learning. This method, termed targeted memory reactivation (TMR), offers a unique opportunity to study the physiological conditions underlying memory reactivation with high temporal precision. In Experiment 1, I used TMR to show that sleep spindles---short bursts of electroencephalographic activity thought to underlie memory processing---increase after presenting learning-related sound cues and predict later memory retention. In Experiment 2, I showed that oscillating auditory rhythms presented during sleep increase spindles in a frequency- and topographically-specific manner. In Experiment 3, I combined these two methods by playing oscillating rhythms shortly after sound cues to investigate a possible causal role for sleep spindles. Although the oscillating rhythm did not alter memory storage, it disrupted the predictive role for spindles in memory. These findings significantly contribute to understanding how sleep benefits memory and could aid in developing memory-augmenting methods in populations suffering from poor memory.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9781321633887Subjects--Topical Terms:

593561
Neurosciences.
Index Terms--Genre/Form:

554714
Electronic books.

Mechanisms of Memory Reactivation during Sleep.
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100 1 $a Antony, James. $3 1186740
245 1 0 $a Mechanisms of Memory Reactivation during Sleep.
264 0 $c 2015
300 $a 1 online resource (141 pages)
336 $a text $b txt $2 rdacontent
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500 $a Source: Dissertation Abstracts International, Volume: 76-08(E), Section: B.
500 $a Adviser: Paul J. Reber.
502 $a Thesis (Ph.D.)--Northwestern University, 2015.
504 $a Includes bibliographical references
520 $a Repeatedly visiting memories prevents their decay into oblivion. This repetition certainly occurs while a person is awake, but a strong body of evidence shows it also occurs spontaneously during sleep. A fundamental aspect of this idea is that newly formed hippocampal memory traces become reactivated during sleep, suggesting sleep plays an active, qualitatively distinct step in the long-term preservation of memories. Moreover, memory reactivation can apparently be induced during post-learning sleep by presenting stimuli that had previously been associated with learning. This method, termed targeted memory reactivation (TMR), offers a unique opportunity to study the physiological conditions underlying memory reactivation with high temporal precision. In Experiment 1, I used TMR to show that sleep spindles---short bursts of electroencephalographic activity thought to underlie memory processing---increase after presenting learning-related sound cues and predict later memory retention. In Experiment 2, I showed that oscillating auditory rhythms presented during sleep increase spindles in a frequency- and topographically-specific manner. In Experiment 3, I combined these two methods by playing oscillating rhythms shortly after sound cues to investigate a possible causal role for sleep spindles. Although the oscillating rhythm did not alter memory storage, it disrupted the predictive role for spindles in memory. These findings significantly contribute to understanding how sleep benefits memory and could aid in developing memory-augmenting methods in populations suffering from poor memory.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Neurosciences. $3 593561
650 4 $a Cognitive psychology. $3 556029
655 7 $a Electronic books. $2 local $3 554714
690 $a 0317
690 $a 0633
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a Northwestern University. $b Neuroscience Institute Graduate Program. $3 1186741
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3686585 $z click for full text (PQDT)