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Patent Ductus Arteriosus Ligation in...

Weisz, Dany.

Patent Ductus Arteriosus Ligation in Extremely Preterm Infants and Death or Neurodevelopmental Impairment.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Patent Ductus Arteriosus Ligation in Extremely Preterm Infants and Death or Neurodevelopmental Impairment./
Author:	Weisz, Dany.
Description:	1 online resource (132 pages)
Notes:	Source: Masters Abstracts International, Volume: 56-03.
Subject:	Medicine. -
Online resource:	click for full text (PQDT)
ISBN:	9781369666489

Patent Ductus Arteriosus Ligation in Extremely Preterm Infants and Death or Neurodevelopmental Impairment.
Weisz, Dany.

Patent Ductus Arteriosus Ligation in Extremely Preterm Infants and Death or Neurodevelopmental Impairment. - 1 online resource (132 pages)

Source: Masters Abstracts International, Volume: 56-03.

Thesis (M.Sc.)--University of Toronto (Canada), 2016.

Includes bibliographical references

Objective: Evaluate the association between patent ductus arteriosus (PDA) ligation vs. medical management and neonatal and neurodevelopmental outcomes.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9781369666489Subjects--Topical Terms:

644133
Medicine.
Index Terms--Genre/Form:

554714
Electronic books.

Patent Ductus Arteriosus Ligation in Extremely Preterm Infants and Death or Neurodevelopmental Impairment.
LDR:02375ntm a2200373K 4500 001 915793
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008 190606s2016 xx obm 000 0 eng d
020 $a 9781369666489
035 $a (MiAaPQ)AAI10194545
035 $a (MiAaPQ)toronto:14678
035 $a AAI10194545
040 $a MiAaPQ $b eng $c MiAaPQ
100 1 $a Weisz, Dany. $3 1189297
245 1 0 $a Patent Ductus Arteriosus Ligation in Extremely Preterm Infants and Death or Neurodevelopmental Impairment.
264 0 $c 2016
300 $a 1 online resource (132 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Masters Abstracts International, Volume: 56-03.
500 $a Adviser: Prakesh S. Shah.
502 $a Thesis (M.Sc.)--University of Toronto (Canada), 2016.
504 $a Includes bibliographical references
520 $a Objective: Evaluate the association between patent ductus arteriosus (PDA) ligation vs. medical management and neonatal and neurodevelopmental outcomes.
520 $a Methods: Retrospective cohort study of extremely preterm infants with PDA born between 2006-2012. The primary outcome was death or neurodevelopmental impairment (NDI) at 18-24 months. Secondary outcomes included death, chronic lung disease (CLD), and NDI. Multivariable logistic regression (MLR) analysis and marginal structural models (MSM) were used to adjust for perinatal and postnatal confounders.
520 $a Results: Of 754 infants with PDA, 184(24%) underwent ligation. Compared with medically treated infants, ligated infants had similar odds of death/NDI (aOR 0.83, 95%CI:0.52-1.32), NDI (aOR 1.27, 95%CI:0.78--2.06), and CLD (aOR 1.36, 95%CI:0.78--2.39), but lower mortality (aOR 0.09, 95%CI:0.04--0.21).
520 $a Conclusions: PDA ligation is not associated with adverse outcomes and may reduce mortality. Previously reported associations of ligation with increased morbidity are likely due to bias from confounding by indication, rather than a detrimental causal effect of ligation.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Medicine. $3 644133
650 4 $a Epidemiology. $3 635923
650 4 $a Biostatistics. $3 783654
655 7 $a Electronic books. $2 local $3 554714
690 $a 0564
690 $a 0766
690 $a 0308
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a University of Toronto (Canada). $b Health Policy, Management and Evaluation. $3 1189298
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10194545 $z click for full text (PQDT)

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