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Effect of Dietary Source and Concentrations of Copper, Manganese, and Zinc on Growth Performance asnd Immune Response of Nursery Pigs.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Effect of Dietary Source and Concentrations of Copper, Manganese, and Zinc on Growth Performance asnd Immune Response of Nursery Pigs./
Author:	Schaaf, Silvia.
Description:	1 online resource (163 pages)
Notes:	Source: Masters Abstracts International, Volume: 57-01.
Contained By:	Masters Abstracts International57-01(E).
Subject:	Animal sciences. -
Online resource:	click for full text (PQDT)
ISBN:	9780355394078

Effect of Dietary Source and Concentrations of Copper, Manganese, and Zinc on Growth Performance asnd Immune Response of Nursery Pigs.
Schaaf, Silvia.

Effect of Dietary Source and Concentrations of Copper, Manganese, and Zinc on Growth Performance asnd Immune Response of Nursery Pigs. - 1 online resource (163 pages)

Source: Masters Abstracts International, Volume: 57-01.

Thesis (M.S.)--Oklahoma State University, 2017.

Includes bibliographical references

Two experiments were conducted to evaluate dietary source and concentrations of copper, manganese, and zinc on growth performance and the immune response of nursery pigs. Experiment 1 and 2 evaluated two sources of copper, manganese, and zinc: sulfate and chloride. Both sources were then evaluated in two dietary concentrations. To study the acute immune response, all pigs in both experiments were subjected to acute immune challenge by single intraperitoneal injection of lipopolysaccharide (LPS). Additionally, pigs from experiment 2 were subjected to multiple intramuscular injections of LPS to evaluate the chronic immune response. The data from experiment 1 and 2 relative to growth performance and acute immune challenge were combined for statistical analysis. Overall, BW, ADG, ADFI, and G:F ratio were not different among dietary treatment groups. Following the acute immune challenge, pigs fed both dietary concentrations of chlorides produced lower concentrations of TNF-alpha and IL-1beta. A concentration effect was also observed, with higher dietary concentrations of both sources producing less TNF-alpha and IL-1beta. Total-SOD activity was not affected by dietary treatments following the acute immune challenge. During the multiple LPS injections, growth performance was negatively affected; however, no differences were observed among dietary treatment groups. Numerically, TNF-alpha concentration was lower and total-SOD activity was greater in both dietary concentrations of chlorides. IL-1beta was not affected by dietary treatment group during the chronic immune challenge. In conclusion, chloride sources are able to alleviate the acute immune response by decreasing the proinflammatory cytokine production regardless of the dietary concentration, suggesting a higher bioavailability over sulfate sources. Besides that, high dietary concentration of copper, manganese, and zinc showed more promising results, indicating that the immune response may have a greater requirement than that needed for growth. Following a chronic immune challenge, chloride sources showed a numerical advantage over sulfates, suggesting less stimulation of the inflammatory response.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9780355394078Subjects--Topical Terms:

1178863
Animal sciences.
Index Terms--Genre/Form:

554714
Electronic books.

Effect of Dietary Source and Concentrations of Copper, Manganese, and Zinc on Growth Performance asnd Immune Response of Nursery Pigs.
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504 $a Includes bibliographical references
520 $a Two experiments were conducted to evaluate dietary source and concentrations of copper, manganese, and zinc on growth performance and the immune response of nursery pigs. Experiment 1 and 2 evaluated two sources of copper, manganese, and zinc: sulfate and chloride. Both sources were then evaluated in two dietary concentrations. To study the acute immune response, all pigs in both experiments were subjected to acute immune challenge by single intraperitoneal injection of lipopolysaccharide (LPS). Additionally, pigs from experiment 2 were subjected to multiple intramuscular injections of LPS to evaluate the chronic immune response. The data from experiment 1 and 2 relative to growth performance and acute immune challenge were combined for statistical analysis. Overall, BW, ADG, ADFI, and G:F ratio were not different among dietary treatment groups. Following the acute immune challenge, pigs fed both dietary concentrations of chlorides produced lower concentrations of TNF-alpha and IL-1beta. A concentration effect was also observed, with higher dietary concentrations of both sources producing less TNF-alpha and IL-1beta. Total-SOD activity was not affected by dietary treatments following the acute immune challenge. During the multiple LPS injections, growth performance was negatively affected; however, no differences were observed among dietary treatment groups. Numerically, TNF-alpha concentration was lower and total-SOD activity was greater in both dietary concentrations of chlorides. IL-1beta was not affected by dietary treatment group during the chronic immune challenge. In conclusion, chloride sources are able to alleviate the acute immune response by decreasing the proinflammatory cytokine production regardless of the dietary concentration, suggesting a higher bioavailability over sulfate sources. Besides that, high dietary concentration of copper, manganese, and zinc showed more promising results, indicating that the immune response may have a greater requirement than that needed for growth. Following a chronic immune challenge, chloride sources showed a numerical advantage over sulfates, suggesting less stimulation of the inflammatory response.
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