語系:
繁體中文
English
說明(常見問題)
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
The Broader Autism Phenotype in Pare...
~
Rubenstein, Eric.
The Broader Autism Phenotype in Parents of Children with Autism Spectrum Disorder : = Implications for the Diagnostic Process and Relationship to Child Autism Spectrum Disorder Phenotype.
紀錄類型:
書目-語言資料,手稿 : Monograph/item
正題名/作者:
The Broader Autism Phenotype in Parents of Children with Autism Spectrum Disorder :/
其他題名:
Implications for the Diagnostic Process and Relationship to Child Autism Spectrum Disorder Phenotype.
作者:
Rubenstein, Eric.
面頁冊數:
1 online resource (209 pages)
附註:
Source: Dissertation Abstracts International, Volume: 79-01(E), Section: B.
Contained By:
Dissertation Abstracts International79-01B(E).
標題:
Epidemiology. -
電子資源:
click for full text (PQDT)
ISBN:
9780355178678
The Broader Autism Phenotype in Parents of Children with Autism Spectrum Disorder : = Implications for the Diagnostic Process and Relationship to Child Autism Spectrum Disorder Phenotype.
Rubenstein, Eric.
The Broader Autism Phenotype in Parents of Children with Autism Spectrum Disorder :
Implications for the Diagnostic Process and Relationship to Child Autism Spectrum Disorder Phenotype. - 1 online resource (209 pages)
Source: Dissertation Abstracts International, Volume: 79-01(E), Section: B.
Thesis (Ph.D.)--The University of North Carolina at Chapel Hill, 2017.
Includes bibliographical references
Parents of children diagnosed with autism spectrum disorder (ASD) often exhibit social tendencies similar to ASD, but functioning is not impaired nor reaches levels of clinical significance. This constellation of sub-threshold diagnostic ASD traits is referred to as the broader autism phenotype (BAP) and includes features like pragmatic and communication difficulties and poor social skills. BAP is more common in families with children who have ASD and has neurological components and genetic origins, which make it a promising area for etiologic ASD research.
Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018
Mode of access: World Wide Web
ISBN: 9780355178678Subjects--Topical Terms:
635923
Epidemiology.
Index Terms--Genre/Form:
554714
Electronic books.
The Broader Autism Phenotype in Parents of Children with Autism Spectrum Disorder : = Implications for the Diagnostic Process and Relationship to Child Autism Spectrum Disorder Phenotype.
LDR
:03651ntm a2200361Ki 4500
001
917508
005
20181022104648.5
006
m o u
007
cr mn||||a|a||
008
190606s2017 xx obm 000 0 eng d
020
$a
9780355178678
035
$a
(MiAaPQ)AAI10277792
035
$a
(MiAaPQ)unc:17104
035
$a
AAI10277792
040
$a
MiAaPQ
$b
eng
$c
MiAaPQ
$d
NTU
100
1
$a
Rubenstein, Eric.
$3
1191581
245
1 4
$a
The Broader Autism Phenotype in Parents of Children with Autism Spectrum Disorder :
$b
Implications for the Diagnostic Process and Relationship to Child Autism Spectrum Disorder Phenotype.
264
0
$c
2017
300
$a
1 online resource (209 pages)
336
$a
text
$b
txt
$2
rdacontent
337
$a
computer
$b
c
$2
rdamedia
338
$a
online resource
$b
cr
$2
rdacarrier
500
$a
Source: Dissertation Abstracts International, Volume: 79-01(E), Section: B.
500
$a
Adviser: Julie L. Daniels.
502
$a
Thesis (Ph.D.)--The University of North Carolina at Chapel Hill, 2017.
504
$a
Includes bibliographical references
520
$a
Parents of children diagnosed with autism spectrum disorder (ASD) often exhibit social tendencies similar to ASD, but functioning is not impaired nor reaches levels of clinical significance. This constellation of sub-threshold diagnostic ASD traits is referred to as the broader autism phenotype (BAP) and includes features like pragmatic and communication difficulties and poor social skills. BAP is more common in families with children who have ASD and has neurological components and genetic origins, which make it a promising area for etiologic ASD research.
520
$a
The purpose of this dissertation was to explore two questions related to BAP in parents of children with ASD: 1) to assess the effect of BAP on discordance between maternal reported and clinician observed or estimated instruments reporting child ASD and 2) examine whether child ASD phenotype differs by parental BAP status. Data from the Study to Explore Early Development, a multi-site, community-based, case-control study of children aged 3-5 years with ASD, were used for all analyses.
520
$a
For our first aim, we used a sample of 712 mother-child dyads referred to SEED from educational and health providers of children with developmental delays who completed BAP and child ASD evaluations. BAP was positively associated with mothers meeting thresholds for child ASD on screeners or interviews when clinician reported instruments of child ASD did not (Risk ratios ranging from 1.45 to 2.52). Reporting discordances should be acknowledged and accounted for when diagnosing ASD.
520
$a
In aim two, we used SEED data to derive latent classes for child ASD phenotype from multiple behavioral and developmental measures. BAP in at least one parent was associated with the child having increased odds of being in the class with average non-verbal functioning, mild language and motor delays, and co-occurring conditions like anxiety and depression (OR: 2.44, 95% CI: 1.16, 5.09). Exploratory analyses show similar results if the father alone had BAP. Child sex did not modify this relationship. Children of parents with BAP were more likely to have a phenotype qualitatively similar to BAP presentation; this may have implications for work exploring etiologic origins and crafting parent-mediated interventions.
533
$a
Electronic reproduction.
$b
Ann Arbor, Mich. :
$c
ProQuest,
$d
2018
538
$a
Mode of access: World Wide Web
650
4
$a
Epidemiology.
$3
635923
655
7
$a
Electronic books.
$2
local
$3
554714
690
$a
0766
710
2
$a
ProQuest Information and Learning Co.
$3
1178819
710
2
$a
The University of North Carolina at Chapel Hill.
$b
Epidemiology.
$3
1183143
773
0
$t
Dissertation Abstracts International
$g
79-01B(E).
856
4 0
$u
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10277792
$z
click for full text (PQDT)
筆 0 讀者評論
多媒體
評論
新增評論
分享你的心得
Export
取書館別
處理中
...
變更密碼[密碼必須為2種組合(英文和數字)及長度為10碼以上]
登入