國立虎尾科技大學 |

Palladium Norbornene Cooperative Catalysis.

紀錄類型:	書目-語言資料,手稿 : Monograph/item
正題名/作者:	Palladium Norbornene Cooperative Catalysis./
作者:	Dong, Zhe.
面頁冊數:	1 online resource (510 pages)
附註:	Source: Dissertation Abstracts International, Volume: 79-08(E), Section: B.
Contained By:	Dissertation Abstracts International79-08B(E).
標題:	Chemistry. -
電子資源:	click for full text (PQDT)
ISBN:	9780355804171

Palladium Norbornene Cooperative Catalysis.
Dong, Zhe.

Palladium Norbornene Cooperative Catalysis. - 1 online resource (510 pages)

Source: Dissertation Abstracts International, Volume: 79-08(E), Section: B.

Thesis (Ph.D.)--The University of Chicago, 2018.

Includes bibliographical references

Chapter 1 introduce the historical background and discovery of Palladium/Norbornene cooperative catalysis. Catellani and coworkers did systematic organometallic study and catalytic system study to prove the concept and mechanism of palladium/norbornene cooperative catalysis. Detailed organometallic study and correct mechanism proposal provide were discussed. Electrophile constraint, aryl iodide constraint, ortho constraint are three major limitations for the Palladium/Norbornene cooperative catalysis.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9780355804171Subjects--Topical Terms:

593913
Chemistry.
Index Terms--Genre/Form:

554714
Electronic books.

Palladium Norbornene Cooperative Catalysis.
LDR:03686ntm a2200385Ki 4500 001 918358
005 20181114145236.5
006 m o u
007 cr mn||||a|a||
008 190606s2018 xx obm 000 0 eng d
020 $a 9780355804171
035 $a (MiAaPQ)AAI10746794
035 $a (MiAaPQ)uchicago:14208
035 $a AAI10746794
040 $a MiAaPQ $b eng $c MiAaPQ $d NTU
100 1 $a Dong, Zhe. $3 1192660
245 1 0 $a Palladium Norbornene Cooperative Catalysis.
264 0 $c 2018
300 $a 1 online resource (510 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Dissertation Abstracts International, Volume: 79-08(E), Section: B.
500 $a Adviser: Guangbin Dong.
502 $a Thesis (Ph.D.)--The University of Chicago, 2018.
504 $a Includes bibliographical references
520 $a Chapter 1 introduce the historical background and discovery of Palladium/Norbornene cooperative catalysis. Catellani and coworkers did systematic organometallic study and catalytic system study to prove the concept and mechanism of palladium/norbornene cooperative catalysis. Detailed organometallic study and correct mechanism proposal provide were discussed. Electrophile constraint, aryl iodide constraint, ortho constraint are three major limitations for the Palladium/Norbornene cooperative catalysis.
520 $a Chapter 2 describe a palladium/norbornene-catalyzed ortho-arene amination to introduce amine at ortho position of aryl iodide and hydrogen atom at the ipso position. O-benzoyloxyamines and iso-propanol are employed as the amine source (oxidant) and reductant respectively. This transformation gives complementary site-selectivity at the ortho instead of the ipso -position of aryl halides with high functional group tolerance.
520 $a Chapter 3 describe a palladium/norbornene-catalyzed ortho-arene acylation of aryl iodides via Catellani-type C--H functionalization. This transformation is enabled by isopropyl carbonate anhydrides as a dual functional reagent serving as both an acyl cation equivalent and a hydride source.
520 $a Chapter 4 describe the development of general approaches for aryl bromide-mediated Pd/NBE cooperative catalysis. Ortho amination, acylation and alkylation of aryl bromides have all been realized in good efficiency. Importantly, various heteroarene substrates also work well and a wide range of functional groups are tolerated. Sequential cross coupling/ortho functionalization reactions and consecutive palladium/norbornene-catalyzed difunctionalization to construct penta-substituted aromatics and two-step meta-functionalization reactions are achieved.
520 $a Chapter 5 describe a highly meta-selective C?H arylation using simple tertiary amines as the directing group. This method takes advantages of Pd/norbornene catalysis offering a distinct strategy to control the site-selectivity. The reaction was promoted by commercially available AsPh3 ligand and unique "acetate cocktail". Aryl iodides with an ortho-electron withdrawing group were employed as the coupling partner. A wide range of functional groups, including some heteroarenes, can be tolerated under the reaction conditions. The amine directing group can be easily installed and trans-formed to other common versatile functional groups.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Chemistry. $3 593913
650 4 $a Organic chemistry. $3 1148722
655 7 $a Electronic books. $2 local $3 554714
690 $a 0485
690 $a 0490
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a The University of Chicago. $b Chemistry. $3 1187113
773 0 $t Dissertation Abstracts International $g 79-08B(E).
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10746794 $z click for full text (PQDT)