國立虎尾科技大學 |

A Multi-Method Exploration of the Genetic and Environmental Risks Contributing to Tobacco Use Behaviors in Young Adulthood.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	A Multi-Method Exploration of the Genetic and Environmental Risks Contributing to Tobacco Use Behaviors in Young Adulthood./
Author:	Do, Elizabeth Kieuvan.
Description:	1 online resource (309 pages)
Notes:	Source: Dissertation Abstracts International, Volume: 78-10(E), Section: B.
Contained By:	Dissertation Abstracts International78-10B(E).
Subject:	Behavioral sciences. -
Online resource:	click for full text (PQDT)
ISBN:	9781369813258

A Multi-Method Exploration of the Genetic and Environmental Risks Contributing to Tobacco Use Behaviors in Young Adulthood.
Do, Elizabeth Kieuvan.

A Multi-Method Exploration of the Genetic and Environmental Risks Contributing to Tobacco Use Behaviors in Young Adulthood. - 1 online resource (309 pages)

Source: Dissertation Abstracts International, Volume: 78-10(E), Section: B.

Thesis (Ph.D.)--Virginia Commonwealth University, 2017.

Includes bibliographical references

Tobacco use remains the leading preventable cause of morbidity and mortality in both the United States and worldwide. Twin and family studies have demonstrated that both genetic and environmental factors are important contributors to tobacco use behaviors. Understanding how genes, the environment, and their interactions is critical to the development of public health interventions that focus on the reduction of tobacco-related morbidity and mortality. However, few studies have examined the transition from adolescent to young adulthood---the time when many individuals are experimenting with and developing patterns of tobacco use. This thesis seeks to provide a comprehensive set of studies looking at risk for tobacco use behaviors and nicotine dependence using samples of young adults. The first aim is to examine the joint contributions of genetic liability and environmental contexts on tobacco use in adolescence and young adulthood using classical twin study methodologies. The second goal is to identify genetic variants and quantifying genetic risk for tobacco use in young adulthood and examining their interaction with environmental context across development. Accordingly, the thesis is divided up into the following sections: i) reviews of existing literature on genes, environment, and tobacco use; ii) twin studies of genetic and environmental influences on tobacco use behavior phenotypes; iii) prevalence, correlates, and predictors of tobacco use behaviors; iv) genetic analyses of tobacco use behaviors; v) a commentary on the emergence of alternative nicotine delivery systems and its public health impacts; and vi) plans for an internet-based educational intervention seeking to reduce tobacco use (and nicotine dependence) by providing students attending university with information on genetic and environmental risk factors for nicotine dependence.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9781369813258Subjects--Topical Terms:

1148596
Behavioral sciences.
Index Terms--Genre/Form:

554714
Electronic books.

A Multi-Method Exploration of the Genetic and Environmental Risks Contributing to Tobacco Use Behaviors in Young Adulthood.
LDR:03181ntm a2200349Ki 4500 001 920632
005 20181203094030.5
006 m o u
007 cr mn||||a|a||
008 190606s2017 xx obm 000 0 eng d
020 $a 9781369813258
035 $a (MiAaPQ)AAI10281656
035 $a (MiAaPQ)vcu:11630
035 $a AAI10281656
040 $a MiAaPQ $b eng $c MiAaPQ $d NTU
100 1 $a Do, Elizabeth Kieuvan. $3 1195490
245 1 2 $a A Multi-Method Exploration of the Genetic and Environmental Risks Contributing to Tobacco Use Behaviors in Young Adulthood.
264 0 $c 2017
300 $a 1 online resource (309 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Dissertation Abstracts International, Volume: 78-10(E), Section: B.
500 $a Adviser: Hermine H. Maes.
502 $a Thesis (Ph.D.)--Virginia Commonwealth University, 2017.
504 $a Includes bibliographical references
520 $a Tobacco use remains the leading preventable cause of morbidity and mortality in both the United States and worldwide. Twin and family studies have demonstrated that both genetic and environmental factors are important contributors to tobacco use behaviors. Understanding how genes, the environment, and their interactions is critical to the development of public health interventions that focus on the reduction of tobacco-related morbidity and mortality. However, few studies have examined the transition from adolescent to young adulthood---the time when many individuals are experimenting with and developing patterns of tobacco use. This thesis seeks to provide a comprehensive set of studies looking at risk for tobacco use behaviors and nicotine dependence using samples of young adults. The first aim is to examine the joint contributions of genetic liability and environmental contexts on tobacco use in adolescence and young adulthood using classical twin study methodologies. The second goal is to identify genetic variants and quantifying genetic risk for tobacco use in young adulthood and examining their interaction with environmental context across development. Accordingly, the thesis is divided up into the following sections: i) reviews of existing literature on genes, environment, and tobacco use; ii) twin studies of genetic and environmental influences on tobacco use behavior phenotypes; iii) prevalence, correlates, and predictors of tobacco use behaviors; iv) genetic analyses of tobacco use behaviors; v) a commentary on the emergence of alternative nicotine delivery systems and its public health impacts; and vi) plans for an internet-based educational intervention seeking to reduce tobacco use (and nicotine dependence) by providing students attending university with information on genetic and environmental risk factors for nicotine dependence.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Behavioral sciences. $3 1148596
650 4 $a Behavioral psychology. $3 1179418
650 4 $a Statistics. $3 556824
655 7 $a Electronic books. $2 local $3 554714
690 $a 0602
690 $a 0384
690 $a 0463
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a Virginia Commonwealth University. $b Clinical and Translational Sciences. $3 1189238
773 0 $t Dissertation Abstracts International $g 78-10B(E).
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10281656 $z click for full text (PQDT)