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Extracellular matrix in tumor biology

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Extracellular matrix in tumor biology/ edited by Rolf A. Brekken, Dwayne Stupack.
other author:	Brekken, Rolf A.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	ix, 115 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Extracellular matrix. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-60907-2
ISBN:	9783319609072

Extracellular matrix in tumor biology
Extracellular matrix in tumor biology[electronic resource] /edited by Rolf A. Brekken, Dwayne Stupack. - Cham :Springer International Publishing :2017. - ix, 115 p. :ill., digital ;24 cm. - Biology of extracellular matrix,0887-3224. - Biology of extracellular matrix..

1. The extracellular matrix of tumors: a focus on fibronectin and fibulin-5 -- 2. Internalization of collagen: an important matrix turnover pathway in cancer -- 3. Lumican, a Small Leucine-Rich Proteoglycan, and Its Biological Function in Tumor Progression -- 4. Versican: Role in Cancer Tumorigenesis -- 5. Engineering advanced models of the glioblastoma microenvironment using biomaterials -- 6. Breaching and opening basement membrane barriers: the anchor cell leads the way.

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression. The book addresses researchers working on cancer biology or ECM, and oncologists alike.

ISBN: 9783319609072

Standard No.: 10.1007/978-3-319-60907-2doiSubjects--Topical Terms:

784547
Extracellular matrix.

LC Class. No.: QH603.E93

Dewey Class. No.: 572.6

Extracellular matrix in tumor biology
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245 0 0 $a Extracellular matrix in tumor biology $h [electronic resource] / $c edited by Rolf A. Brekken, Dwayne Stupack.
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300 $a ix, 115 p. : $b ill., digital ; $c 24 cm.
490 1 $a Biology of extracellular matrix, $x 0887-3224
505 0 $a 1. The extracellular matrix of tumors: a focus on fibronectin and fibulin-5 -- 2. Internalization of collagen: an important matrix turnover pathway in cancer -- 3. Lumican, a Small Leucine-Rich Proteoglycan, and Its Biological Function in Tumor Progression -- 4. Versican: Role in Cancer Tumorigenesis -- 5. Engineering advanced models of the glioblastoma microenvironment using biomaterials -- 6. Breaching and opening basement membrane barriers: the anchor cell leads the way.
520 $a This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression. The book addresses researchers working on cancer biology or ECM, and oncologists alike.
650 0 $a Extracellular matrix. $3 784547
650 0 $a Tumors. $3 676261
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Cancer Research. $3 668358
650 2 4 $a Immunology. $3 592892
650 2 4 $a Molecular Medicine. $3 668353
650 2 4 $a Oncology. $3 593951
650 2 4 $a Receptors. $3 787639
650 2 4 $a Cell Biology. $3 593889
700 1 $a Brekken, Rolf A. $3 1199695
700 1 $a Stupack, Dwayne. $3 1199696
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